KEGG ENZYME: 2.1.1.273

ENZYME: 2.1.1.273

Entry

EC 2.1.1.273                Enzyme

Name

benzoate O-methyltransferase;
BAMT;
S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:benzoate O-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + benzoate = S-adenosyl-L-homocysteine + methyl benzoate [RN:R10447]

Reaction(KEGG)

R10447

Substrate

S-adenosyl-L-methionine [CPD:C00019];
benzoate [CPD:C00180]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
methyl benzoate [CPD:C20645]

Comment

While the enzyme from the plant Zea mays is specific for benzoate [6], the enzymes from Arabidopsis species and Clarkia breweri also catalyse the reaction of EC 2.1.1.274, salicylate 1-O-methyltransferase [1,5]. In snapdragon (Antirrhinum majus) two isoforms are found, one specific for benzoate [2,3] and one that is also active towards salicylate [4]. The volatile product is an important scent compound in some flowering species [2].

History

EC 2.1.1.273 created 2013

Orthology

K21482

benzoate O-methyltransferase

K21484

benzoate/salicylate 1-O-methyltransferase

Genes

ATH:	AT3G11480(BSMT1) AT5G04370(NAMT1) AT5G04380 AT5G66430

ALY:

9320913

CRB:

17893670

CSAT:

104708682 104727399 104734448 104745350 104745353 104745842 104746543 104762932 104764901 104766009 104768626 104773442 109130817

EUS:	EUTSA_v10013754mg EUTSA_v10022292mg

BRP:	103837152 103847295 103847297 103847298 103847299 103855566 103859391 103870342 103870344

BNA:	106345178 106345495 106346584 106353051 106364005 106366900 106370700 106372697 106372698 106416291 106416341 106423452 106436478 106436480 106436482 106442990 111215744

BOE:	106302931 106313641 106316499 106318326 106318327 106329214 106332554

RSZ:	108816075 108816378 108818257 108846057 108857765 108859694 108860654 108861249

THJ:	104819197 104819198 104820147

CPAP:

110822348 110822461 110826209

CIT:

102625129

TCC:

18589945

GRA:

105775995

GHI:	107915639 107953092

HSYR:

120174589 120193507 120206452 120206462 120206925 120206936

DZI:

111309877

POP:

18108185

PEU:

105133897

PALZ:

118056955

JRE:

108983849

VVI:	100249594 100266757

VRI:	117912404 117913130 117913186

SLY:	101254028 101254332

SPEN:

107001190 107015380 107015389

SOT:	102597978 102598302 102598971 102599293

SSTN:

125853574 125853577 125862721

SDUL:

129886835

CANN:

107857182

LBB:	132599905 132644297 132645153

NTA:	107766085 107799152

NSY:

104246528

NTO:

104120721

SIND:

105173412 105173413 105173418 105173794

EGT:	105952352 105954778 105954779 105966293

APAN:

127246809 127246960 127260537 127260544 127262743 127262789 127262796 127262877

HAN:	110889844 110889847 110923123

ECAD:

122592138 122592141 122592173 122608325 122608527

LSV:	111906000 111906002 111906004 111906005 111908135 111913950

CCAV:

112504667

DCR:

108203055

CSIN:

114306756 114321136

AEW:	130794310 130794807 130794889

NNU:

104595931

OSA:	9267163 9272356

OBR:

102706569

OGL:	127775761 127776353

TDC:

119339997

TAES:

123157742 123169982

LRD:

124648305

SBI:

110434364

ZMA:	100282829 103628300

SITA:

101766563

SVS:

117845571

PHAI:

112882088

» show all

Reference

1 [PMID:10375393]

Authors

Ross JR, Nam KH, D'Auria JC, Pichersky E

Title

S-Adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme involved in floral scent production and plant defense, represents a new class of plant methyltransferases.

Journal

Arch Biochem Biophys 367:9-16 (1999)
DOI:10.1006/abbi.1999.1255

Reference

2 [PMID:10852939]

Authors

Dudareva N, Murfitt LM, Mann CJ, Gorenstein N, Kolosova N, Kish CM, Bonham C, Wood K

Title

Developmental regulation of methyl benzoate biosynthesis and emission in snapdragon flowers.

Journal

Plant Cell 12:949-61 (2000)
DOI:10.1105/tpc.12.6.949

Sequence

[ag:AAF98284]

Reference

3 [PMID:11051108]

Authors

Murfitt LM, Kolosova N, Mann CJ, Dudareva N

Title

Purification and characterization of S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase, the enzyme responsible for biosynthesis of the volatile ester methyl benzoate in flowers of Antirrhinum majus.

Journal

Arch Biochem Biophys 382:145-51 (2000)
DOI:10.1006/abbi.2000.2008

Reference

4 [PMID:12361714]

Authors

Negre F, Kolosova N, Knoll J, Kish CM, Dudareva N

Title

Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is not involved in floral scent production in snapdragon flowers.

Journal

Arch Biochem Biophys 406:261-70 (2002)
DOI:10.1016/S0003-9861(02)00458-7

Reference

5 [PMID:14617060]

Authors

Chen F, D'Auria JC, Tholl D, Ross JR, Gershenzon J, Noel JP, Pichersky E

Title

An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense.

Journal

Plant J 36:577-88 (2003)
DOI:10.1046/j.1365-313X.2003.01902.x

Sequence

[ath:AT3G11480]