KEGG   ENZYME: 2.1.1.312
Entry
EC 2.1.1.312                Enzyme                                 
Name
25S rRNA (uracil2843-N3)-methyltransferase;
BMT6
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:tRNA (uracil2843-N3)-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + uracil2843 in 25S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil2843 in 25S rRNA
Substrate
S-adenosyl-L-methionine [CPD:C00019];
uracil2843 in 25S rRNA
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N3-methyluracil2843 in 25S rRNA
Comment
The enzyme, described from the yeast Saccharomyces cerevisiae, is involved in ribosome biogenesis.
History
EC 2.1.1.312 created 2014
Orthology
K19308  25S rRNA (uracil2843-N3)-methyltransferase
Genes
SCE: YLR063W(BMT6)
SEUB: DI49_3590
SPAO: SPAR_L01180
AGO: AGOS_ACR222W
ERC: Ecym_1512
KLA: KLLA0_D05203g
KMX: KLMA_70060
LTH: KLTH0G18700g
VPO: Kpol_1058p17
ZRO: ZYRO0F02926g
CGR: CAGL0F01661g
NCS: NCAS_0J00400(NCAS0J00400)
NDI: NDAI_0C06480(NDAI0C06480)
TPF: TPHA_0P00220(TPHA0P00220)
TBL: TBLA_0D02430(TBLA0D02430)
TGB: HG536_0B06720
TDL: TDEL_0C00550(TDEL0C00550)
KAF: KAFR_0D00970(KAFR0D00970)
KNG: KNAG_0L00280(KNAG0L00280)
ZMK: HG535_0D05870
PPA: PAS_chr3_0142
DHA: DEHA2F07634g
PIC: PICST_60045
PGU: PGUG_01440
SPAA: SPAPADRAFT_49492
LEL: PVL30_000123
CAL: CAALFM_CR01780WA(CaO19.2575)
CTP: CTRG_00855
COT: CORT_0A00870
CDU: CD36_26800
CTEN: CANTEDRAFT_116882
YLI: YALI0E32219g
CLU: CLUG_04581
CLUS: A9F13_11g02101
CAUR: CJI96_0003020
SLB: AWJ20_5181(BMT6)
OPA: HPODL_00121
SLUD: SCDLUD_000646
NCR: NCU01329
NTE: NEUTE1DRAFT34580(NEUTE1DRAFT_34580)
SMP: SMAC_04019
PAN: PODANSg8080
PBEL: QC761_202950
PPSD: QC762_202950
PPSP: QC763_202950
PPSA: QC764_202950
TTT: THITE_2106779
MTM: MYCTH_2133149
CTHR: CTHT_0066790
MGR: MGG_02469
PPEI: PpBr36_07058
PGRI: PgNI_05619
TMN: UCRPA7_3450
SSCK: SPSK_05334
FGR: FGSG_06492 FGSG_09999
FPU: FPSE_01768 FPSE_03897
FPOA: FPOAC1_003079 FPOAC1_010193
FVN: FVRRES_03410 FVRRES_11162
FVR: FVEG_02779 FVEG_15243
FOX: FOXG_05351 FOXG_18905
NHE: NECHADRAFT_40591
FFC: NCS54_00681500
FKR: NCS57_00721400
FMU: J7337_005694 J7337_006261
TRE: TRIREDRAFT_29713
TRR: M419DRAFT_80324
MAW: MAC_01146
MAJ: MAA_05588
PCHM: VFPPC_13400
CMT: CCM_03476
AMUS: LMH87_000840 LMH87_001285
PLJ: VFPFJ_09385
PTKZ: JDV02_002316
VAL: VDBG_00637
VDA: VDAG_00250
CFJ: CFIO01_02394
CHIG: CH63R_08741
ELA: UCREL1_7348
PFY: PFICI_07131 PFICI_14734
SSL: SS1G_10258
BFU: BCIN_14g01890(Bcbmt6)
MBE: MBM_00103 MBM_09974
PSCO: LY89DRAFT_583157
GLZ: GLAREA_03368
ANI: ANIA_00685
AFM: AFUA_1G13460
ACT: ACLA_021970
NFI: NFIA_012040
AOR: AO090012000534
ANG: An08g06530
AFV: AFLA_002257
ALUC: AKAW2_30429A
ACHE: ACHE_30466A
APUU: APUU_11340A
PCS: N7525_002933
PDP: PDIP_26550
POU: POX_c03660
TMF: EYB26_002896
TRG: TRUGW13939_09394
CIM: CIMG_05745
CPW: CPC735_024190
URE: UREG_04552
PBL: PAAG_04463
PBN: PADG_04618
ABE: ARB_01752
TVE: TRV_01322
AJE: HCAG_05018
BGH: BDBG_08623
PNO: SNOG_15983
PTE: PTT_15390
BZE: COCCADRAFT_40995
BSC: COCSADRAFT_315908
BOR: COCMIDRAFT_97381
AALT: CC77DRAFT_1026688
ARAB: EKO05_0005532
ZTR: MYCGRDRAFT_15276
PFJ: MYCFIDRAFT_148002
FFU: CLAFUR5_00882
CBET: CB0940_00055
BCOM: BAUCODRAFT_400146
TML: GSTUM_00011092001
CNE: CNE00650
CNB: CNBE0590
CNG: CNAG_02495
CGI: CGB_E0620C
CDEU: CNBG_4194
TMS: TREMEDRAFT_55872 TREMEDRAFT_70672
CCAC: CcaHIS019_0700320(CcaverHIS019_0700320)
WSE: WALSEDRAFT_57897
 » show all
Reference
1  [PMID:24335083]
  Authors
Sharma S, Yang J, Duttmann S, Watzinger P, Kotter P, Entian KD
  Title
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.
  Journal
Nucleic Acids Res 42:3246-60 (2014)
DOI:10.1093/nar/gkt1281
  Sequence
[sce:YLR063W]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.312
IUBMB Enzyme Nomenclature: 2.1.1.312
ExPASy - ENZYME nomenclature database: 2.1.1.312
BRENDA, the Enzyme Database: 2.1.1.312

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Gene (171)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (140)   
   KEGG MGENES (1)   
   RefGene (29)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (15)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (6)   
Protein domain (1)   
   InterPro (1)   
All databases (193)   

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