| Entry |
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| Name |
desmethylxanthohumol 6'-O-methyltransferase;
OMT1 (ambiguous)
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN: R08004]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
desmethylxanthohumol [CPD: C16416]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
xanthohumol [CPD: C16417]
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| Comment |
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
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| History |
EC 2.1.1.338 created 2017
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| Pathway |
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| Orthology |
| K21581 | desmethylxanthohumol 6'-O-methyltransferase |
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| Reference |
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| Authors |
Nagel J, Culley LK, Lu Y, Liu E, Matthews PD, Stevens JF, Page JE |
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| Title |
EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.338 |
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