| Entry |
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| Name |
nocamycin O-methyltransferase;
ncmP (gene name)
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:nocamycin E O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + nocamycin E = S-adenosyl-L-homocysteine + nocamycin I [RN: R12263]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
nocamycin E [CPD: C22046]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
nocamycin I [CPD: C22047]
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| Comment |
The enzyme, isolated from the bacterium Saccharothrix syringae, is involved in the biosynthesis of nocamycin I and nocamycin II.
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| History |
EC 2.1.1.351 created 2018
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| Orthology |
| K23153 | nocamycin O-methyltransferase |
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| Reference |
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| Authors |
Mo X, Gui C, Wang Q |
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| Title |
Elucidation of a carboxylate O-methyltransferase NcmP in nocamycin biosynthetic pathway. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.351 |
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