Entry Name scyllo-inosamine-4-phosphate amidinotransferase;
Class Transferases;BRITE hierarchy
Sysname L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase
Reaction(IUBMB) L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate = L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate [RN:
R03477 ]
Reaction(KEGG) Substrate L-arginine [CPD:
C00062 ];
1-amino-1-deoxy-scyllo-inositol 4-phosphate [CPD:
C01283 ]
Product L-ornithine [CPD:
C00077 ];
1-guanidino-1-deoxy-scyllo-inositol 4-phosphate [CPD:
C01294 ]
Comment 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate, streptamine phosphate and 2-deoxystreptamine phosphate can also act as acceptors; canavanine can act as donor.
History EC 2.1.4.2 created 1976, modified 2001
Pathway ec01110 Biosynthesis of secondary metabolites
Orthology K04340 scyllo-inosamine-4-phosphate amidinotransferase 1
Genes SROC : RGF97_02685 RGF97_30750
» show all Taxonomy Reference Authors Walker MS, Walker JB.
Title Enzymic studies on the biosynthesis of streptomycin. Transamidination of inosamine and streptamine derivatives.
Journal J Biol Chem 241:1262-70 (1966)
Other DBs ExplorEnz - The Enzyme Database: 2.1.4.2
ExPASy - ENZYME nomenclature database: 2.1.4.2
BRENDA, the Enzyme Database: 2.1.4.2
