KEGG   ENZYME: 2.2.1.14
Entry
EC 2.2.1.14                 Enzyme                                 
Name
6-deoxy-6-sulfo-D-fructose transaldolase;
sftT (gene name)
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
Sysname
6-deoxy-6-sulfo-D-fructose:D-glyceraldehyde-3-phosphate glyceronetransferase
Reaction(IUBMB)
6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate = (2S)-3-sulfolactaldehyde + beta-D-fructofuranose 6-phosphate [RN:R12731]
Reaction(KEGG)
R12731
Substrate
6-deoxy-6-sulfo-D-fructose [CPD:C20830];
D-glyceraldehyde 3-phosphate [CPD:C00118]
Product
(2S)-3-sulfolactaldehyde [CPD:C21181];
beta-D-fructofuranose 6-phosphate [CPD:C05345]
Comment
The enzyme, characterized from the bacterium Bacillus aryabhattai SOS1, is involved in a degradation pathway for 6-sulfo-D-quinovose. The enzyme can also use D-erythrose 4-phosphate as the acceptor, forming D-sedoheptulose 7-phosphate.
History
EC 2.2.1.14 created 2021
Orthology
K00617  6-deoxy-6-sulfo-D-fructose transaldolase
Genes
BWH: A9C19_00910
BHK: B4U37_05740
BMQ: BMQ_3648
BMH: BMWSH_1555(talC)
BMUR: ABE28_009840
MEKU: HUW50_07770
MSEM: GMB29_25460
LZY: LZ3411_1762 LZ3411_1862
LSUA: H3M12_11825
LHO: LOOC260_121250(tal)
LOL: LACOL_0643(tal1)
LPD: AYR62_00865
CLB: Clo1100_2825
CARG: RSJ17_01340
RPAY: P0092_15945
CAPR: EQM14_02850
LACY: A4V08_25455
ERE: EUBREC_2596
ERT: EUR_25510
CGO: Corgl_1094
GMR: GmarT_58970(tal_2)
GIM: F1728_15765
GPN: Pan110_58800(tal_2)
GFM: Enr17x_59610(tal_2)
MRI: Mal4_33870(tal_2)
BPO: BP951000_1128
BPJ: B2904_orf206
BPW: WESB_2478
TNA: CTN_1544
TTA: Theth_1765
PHY: AJ81_05175
 » show all
Reference
1  [PMID:32919372]
  Authors
Frommeyer B, Fiedler AW, Oehler SR, Hanson BT, Loy A, Franchini P, Spiteller D, Schleheck D.
  Title
Environmental and Intestinal Phylum Firmicutes Bacteria Metabolize the Plant Sugar Sulfoquinovose via a 6-Deoxy-6-sulfofructose Transaldolase Pathway.
  Journal
iScience 23:101510 (2020)
DOI:10.1016/j.isci.2020.101510
Other DBs
ExplorEnz - The Enzyme Database: 2.2.1.14
IUBMB Enzyme Nomenclature: 2.2.1.14
ExPASy - ENZYME nomenclature database: 2.2.1.14
BRENDA, the Enzyme Database: 2.2.1.14

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Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (191)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (32)   
   KEGG MGENES (158)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (2)   
Protein domain (3)   
   InterPro (3)   
All databases (204)   

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