KEGG   ENZYME: 2.3.1.167
Entry
EC 2.3.1.167                Enzyme                                 
Name
10-deacetylbaccatin III 10-O-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:taxan-10beta-ol O-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III [RN:R06311]
Reaction(KEGG)
R06311
Substrate
acetyl-CoA [CPD:C00024];
10-deacetylbaccatin III [CPD:C11700]
Product
CoA [CPD:C00010];
baccatin III [CPD:C11900]
Comment
The enzyme will not acylate the hydroxy group at 1beta, 7beta or 13alpha of 10-deacetyl baccatin III, or at 5alpha of taxa-4(20),11-dien-5alpha-ol. May be identical to EC 2.3.1.163, 10-hydroxytaxane O-acetyltransferase.
History
EC 2.3.1.167 created 2002
Pathway
ec00904  Diterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K12926  10-deacetylbaccatin III 10-O-acetyltransferase
Reference
1  [PMID:10639122]
  Authors
Walker K, Croteau R
  Title
Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 97:583-7 (2000)
DOI:10.1073/pnas.97.2.583
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.167
IUBMB Enzyme Nomenclature: 2.3.1.167
ExPASy - ENZYME nomenclature database: 2.3.1.167
BRENDA, the Enzyme Database: 2.3.1.167
CAS: 220946-63-4

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