KEGG ENZYME: 2.3.1.197

ENZYME: 2.3.1.197

Entry

EC 2.3.1.197                Enzyme

Name

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase;
FdtC;
dTDP-D-Fucp3N acetylase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase

Reaction(IUBMB)

acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose = CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose [RN:R09873]

Reaction(KEGG)

R09873

Substrate

acetyl-CoA [CPD:C00024];
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose [CPD:C19947]

Product

CoA [CPD:C00010];
dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose [CPD:C20156]

Comment

The product, dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose, is a component of the glycan chain of the crystalline bacterial cell surface layer protein (S-layer glycoprotein) of Aneurinibacillus thermoaerophilus.

History

EC 2.3.1.197 created 2012

Pathway

ec00523

Polyketide sugar unit biosynthesis

ec00541

O-Antigen nucleotide sugar biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K20681

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase

Reference

1 [PMID:12740380]

Authors

Pfoestl A, Hofinger A, Kosma P, Messner P

Title

Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.

Journal

J Biol Chem 278:26410-7 (2003)
DOI:10.1074/jbc.M300858200

Sequence

[ag:AAS55721]

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.197

IUBMB Enzyme Nomenclature:

2.3.1.197

ExPASy - ENZYME nomenclature database:

2.3.1.197

BRENDA, the Enzyme Database:

2.3.1.197

DBGET integrated database retrieval system