KEGG ENZYME: 2.3.1.209

ENZYME: 2.3.1.209

Entry

EC 2.3.1.209                Enzyme

Name

dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase;
VioB

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-glucose N-acetyltransferase

Reaction(IUBMB)

acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose [RN:R10174]

Reaction(KEGG)

R10174

Substrate

acetyl-CoA [CPD:C00024];
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose [CPD:C04268]

Product

CoA [CPD:C00010];
dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose [CPD:C06018]

Comment

The non-activated product, 4-acetamido-4,6-dideoxy-alpha-D-glucose, is part of the O antigens of Shigella dysenteriae type 7 and Escherichia coli O7.

History

EC 2.3.1.209 created 2012

Pathway

ec00541

O-Antigen nucleotide sugar biosynthesis

ec01100

Metabolic pathways

Orthology

K21379

dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase

Genes

ECT:	ECIAI39_0980(vioB)

EBR:	ECB_01941(vioB)

ECOB:

C3029_14345

EBL:	ECD_01941(vioB)

EBE:	B21_01930(ybl96)

EBD:

ECBD_1620

SHQ:	A0259_14010

ESH:	C1N69_14920

EBB:

F652_1772

FSG:	LQ771_03785

ATG:	J4G44_00255

SHE:	Shewmr4_1322

SHW:	Sputw3181_1469

SCHK:

GII14_07750

FSR:	KQR59_07415

AHI:	VU14_07305

ASAA:

KXJ75_15910

MENY:

LSQ66_03935

» show all

Reference

1 [PMID:17905981]

Authors

Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L

Title

Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7.

Journal

J Bacteriol 189:8626-35 (2007)
DOI:10.1128/JB.00777-07

Sequence

[ag:AAD44155]

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.209

IUBMB Enzyme Nomenclature:

2.3.1.209

ExPASy - ENZYME nomenclature database:

2.3.1.209

BRENDA, the Enzyme Database:

2.3.1.209

DBGET integrated database retrieval system