KEGG ENZYME: 2.3.1.264

ENZYME: 2.3.1.264

Entry

EC 2.3.1.264                Enzyme

Name

beta-lysine N6-acetyltransferase;
ablB (gene name)

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:(3S)-3,6-diaminohexanoate N6-acetyltransferase

Reaction(IUBMB)

acetyl-CoA + (3S)-3,6-diaminohexanoate = CoA + (3S)-6-acetamido-3-aminohexanoate [RN:R11701]

Reaction(KEGG)

R11701

Substrate

acetyl-CoA [CPD:C00024];
(3S)-3,6-diaminohexanoate [CPD:C01142]

Product

CoA [CPD:C00010];
(3S)-6-acetamido-3-aminohexanoate [CPD:C21604]

Comment

The enzyme is found in some methanogenic archaea and bacteria. In archaea it is induced under salt stress. The product, N6-acetyl-beta-L-lysine, serves as a compatible solute, conferring high salt resistance on the producing organisms.

History

EC 2.3.1.264 created 2017

Orthology

K21935

beta-lysine N6-acetyltransferase

Genes

SSE:

Ssed_1816

SCAA:

TUM17387_28340

SCHK:

GII14_15645(ablB)

LSD:	EMK97_14325

TVD:	SG34_033320

PSEO:

OM33_16210

PPHE:

PP2015_1237

PLZ:	S4054249_10800

PSPO:

PSPO_b0325

PIN:

Ping_1907

FBL:

Fbal_1214

GEM:

GM21_3127

GEB:

GM18_0332

GBN:	GEOBRER4_13340

GER:	KP004_17565

GNT:	KP003_19225

GPL:	M1B72_20455

GSB:	GSUB_05960

GHC:	L9S41_07315(ablB)

PCA:	Pcar_1402(ablB)

PACE:

A6070_05735

PPD:

Ppro_1080

DEU:	DBW_0847(yodP)

DVE:	DESUT3_13430

DES:	DSOUD_2507

DFL:

DFE_1857

DSB:	LN040_09980(ablB)

DDE:

Dde_0188

DSA:	Desal_3315

DAF:	Desaf_1115

DAS:

Daes_0846

DPI:

BN4_11172

PPRF:

DPRO_1392

PSEL:

GM415_01915(ablB)

DBA:

Dbac_0210

DESU:

NLA06_11900(ablB)

DRT:

Dret_0695

DPS:

DP2160

DAK:	DaAHT2_0564

ECOM:

QTN59_06020(ablB)

DAT:	HRM2_44880

DWD:	DSCW_64840(yodP)

DALK:

DSCA_17980(yodP)

SAT:

SYN_02633

BBAE:

FRD01_12570

BMX:

BMS_0904

BSU:	BSU19700(yodP)

BSR:

I33_2213

BSL:

A7A1_2841

BSH:	BSU6051_19700(yodP)

BSY:	I653_10220

BSUT:

BSUB_02122(yodP)

BSUL:

BSUA_02122(yodP)

BSO:	BSNT_08543(yodP)

BSN:	BSn5_01230

BSQ:	B657_19700(kamB)

BSX:	C663_2028(yodP)

BSP:	U712_10405

BSS:	BSUW23_10540(yodP)

BST:

GYO_2378

BIT:	BIS30_00395

BLI:	BL01429(yodP)

BLD:	BLi02295(yodP)

BLH:	BaLi_c23800(yodP)

BAY:	RBAM_019530(ablB)

BAQ:	BACAU_1954(yodP)

BYA:	BANAU_2077(yodP)

BAMP:

B938_10120

BQY:	MUS_2331(yodP)

BAML:

BAM5036_1885(yodP)

BAMA:

RBAU_1922(kamB)

BAMN:

BASU_1902(kamB)

BAMB:

BAPNAU_1792(yodP)

BAMT:

AJ82_11085

BAMY:

V529_21760(yodP)

BMP:	NG74_02032(yodP)

BAO:	BAMF_2049(yodP)

BAZ:	BAMTA208_07260(yodP)

BQL:	LL3_02152(yodP)

BXH:	BAXH7_01476(yodP)

BAMI:

KSO_009580

BAMC:

U471_20160

BAMF:

U722_10650

BSIA:

CWD84_11245(ablB)

BAE:	BATR1942_08570

BVM:	B9C48_09945

BSON:

S101395_02309(kamA)

BHT:	DIC78_20725(ablB)

BMOJ:

HC660_20360(kamB)

BTEQ:

G4P54_11305(ablB)

BIQ:	AN935_10460

BSTR:

QI003_10665(ablB) QI003_14095(ablB)

BAN:

BA_2298

BAR:

GBAA_2298

BAT:

BAS2143

BAH:	BAMEG_2296

BAI:

BAA_2362

BAX:	H9401_2185

BANT:

A16_23360

BANR:

A16R_23620

BANS:

BAPAT_2198

BANH:

HYU01_11455

BANV:

DJ46_1095(ablB)

BCE:

BC2249

BCA:

BCE_2332

BCZ:	BCE33L2077

BCR:	BCAH187_A2406

BCB:	BCB4264_A2279

BCU:	BCAH820_2323

BCG:	BCG9842_B3044

BCQ:

BCQ_2232

BCX:

BCA_2379

BAL:	BACI_c22590

BNC:

BCN_2226

BCF:

bcf_11510

BCER:

BCK_23350

BCEF:

BcrFT9_01833

BCY:	Bcer98_1686

BTK:	BT9727_2081

BTL:

BALH_2060

BTB:	BMB171_C2027

BTT:

HD73_2538

BTHR:

YBT1520_12415

BTHI:

BTK_12585

BTC:	CT43_CH2215

BTF:	YBT020_11750

BTM:

MC28_1468

BTG:	BTB_c23310

BTI:

BTG_08630

BTN:	BTF1_08750

BTHT:

H175_ch2249

BTHU:

YBT1518_12480

BTW:	BF38_3499(ablB)

BTHY:

AQ980_18375

BWE:	BcerKBAB4_2116

BWW:	bwei_2747(yodP)

BMYO:

BG05_3745(ablB)

BTY:	Btoyo_4881

BMYC:

DJ92_4850(ablB)

BBY:	CY96_10370

BWD:	CT694_12190(ablB)

BTRO:

FJR70_08155(ablB)

BMOB:

MLA2C4_11485(ablB)

BNT:	GSN03_11025(ablB)

BPAC:

LMD38_15265(ablB)

BPAN:

NLJ82_11090(ablB)

BALU:

QRY64_13765(ablB)

BPU:

BPUM_0610

BPUM:

BW16_03365

BPUS:

UP12_03400

BIF:	N288_16195

BMET:

BMMGA3_10140

BGY:

BGLY_2548

BXI:	BK049_04740

BALT:

CFN77_03335(ablB)

BAER:

BAE_10880(ablB)

BSAF:

BSL056_03220

BFD:	NCTC4823_00156

BSHI:

LGQ02_09125(ablB)

BCAB:

EFK13_10900(ablB)

BRY:	M0696_10605(ablB)

BJS:

MY9_2158

BACI:

B1NLA3E_14065

GST:	HW35_02725

BACW:

QR42_03285

BACP:

SB24_18935

BACB:

OY17_12890

BACY:

QF06_08985

BACL:

BS34A_21860(yodP)

BALM:

BsLM_2096

BACS:

AUL54_00640

BACQ:

DOE78_15425(ablB)

BACA:

FAY30_15285(ablB)

BZH:	NF868_02840(ablB)

BHAI:

KJK41_13740(ablB)

BCAO:

LC087_03800(ablB)

BARD:

QRY57_12765(ablB)

BAEI:

RE735_16045(ablB)

BHK:	B4U37_11910

BCOH:

BC6307_10970

BMQ:

BMQ_4041

BMD:

BMD_4026

BMH:	BMWSH_1183

BMEG:

BG04_955(ablB)

BEO:

BEH_06225

BFX:	BC359_07875

PKS:	IE339_06905(ablB)

BHA:

BH2257

BKW:	BkAM31D_12435(yodP)

BGI:	BGM20_04460

BPF:	BpOF4_18620

BON:	A361_18675

BKO:	CKF48_19595(ablB)

CGOT:

J1899_13470(ablB)

CSUA:

IM538_14850(ablB)

CFIR:

NAF01_16805(ablB)

CSOA:

LIS82_17465(ablB)

CSPG:

LS684_12465(ablB) LS684_24035(ablB)

CPSS:

M5V91_02325(ablB)

BDA:	FSZ17_14235(ablB)

ANM:	GFC28_580(ablB)

AAMY:

GFC30_1858(ablB)

ANL:	GFC29_1044(ablB)

AND:	GRQ40_09905(ablB)

ACAI:

ISX45_07260(ablB)

ASED:

IRT44_12700(ablB)

HHD:	HBHAL_3877

HMN:	HM131_14045

FPN:	ABE65_009370

FAR:	ABE41_010655

FEC:	QNH15_12290(ablB)

BSJ:	UP17_14270 UP17_19665

BMUR:

ABE28_013265 ABE28_018460

PBUT:

DTO10_01460(ablB) DTO10_06460(ablB)

PASA:

BAOM_3336

PPSR:

I6J18_22310(ablB)

PFRI:

L8956_14810(ablB) L8956_20310(ablB)

GRC:	GI584_00325(ablB)

GCS:	MUN88_02620(ablB)

NMK:	CHR53_18210(ablB)

NDT:	L1999_19690(ablB)

NCM:	QNK12_21330(ablB)

NNV:	QNH39_16785(ablB)

MEKU:

HUW50_16835(ablB)

MSEM:

GMB29_08205(ablB)

MDG:	K8L98_03085(ablB) K8L98_14360(ablB)

MLIT:

KDJ21_023875(ablB)

MENL:

MVE64_21000(ablB)

MEBZ:

LPC09_07110(ablB)

AIA:	AWH56_019870(ablB)

BVQ:	FHE72_13420(ablB)

RMF:	D5E69_12965(ablB)

RAZ:	U9J35_13630(ablB)

GAJ:	MY490_01865(ablB)

MJO:	FOF60_15350(ablB)

MSUT:

LC048_07205(ablB)

ECTO:

MUG87_02770(ablB)

ALKG:

MOJ78_10590(ablB)

PHJ:	LC071_00210(ablB)

BBE:	BBR47_20910

BLR:	BRLA_c014500(yodP)

BFM:	BP422_05595

BAGR:

BA6348_18640(ablB)

BRW:	GOP56_00175(ablB)

BCHS:

JNE38_11025(ablB)

BCOP:

JD108_14080(ablB)

BPAB:

PSE45_10305(ablB)

BHUI:

LOK74_11800(ablB)

BAYD:

BSPP4475_12810(ablB)

BBOR:

RFB14_16460(ablB)

BRUM:

NDK47_16860(ablB)

PALB:

EJC50_16270(ablB)

ANX:	ACH33_16675

ASOC:

CB4_04199(yodP)

ATHE:

K3F53_02170(ablB)

COH:	EAV92_13085(ablB)

TUM:	CBW65_01280

PANC:

E2636_15740(ablB)

LFB:	C1X05_08465(ablB)

TVU:	AB849_006385(ablB)

CBE:	Cbei_1453 Cbei_2936

CBZ:	Cbs_1453 Cbs_2936

CBEI:

LF65_01557

CPAS:

Clopa_3529 Clopa_3775

CPAT:

CLPA_c13710(ablB)

CPAE:

CPAST_c13710(ablB)

CSQ:

CSCA_2502

CLD:	CLSPO_c15730(ablB)

CCK:	Ccar_02205

CTYK:

CTK_C05930

CTAE:

BGI42_06410(ablB)

CDRK:

B9W14_07190

CDY:	F3K33_07525(ablB) F3K33_14930(ablB)

CFER:

D4Z93_09495(ablB)

CLOS:

DMR38_14955(ablB) DMR38_19200(ablB)

CINT:

HZF06_03330(ablB)

HSC:	HVS_06555(yodP)

RPAY:

P0092_11220(ablB)

PETR:

QKW49_14130(ablB)

SALQ:

SYNTR_1222

DOR:	Desor_2830 Desor_4630

DMI:	Desmer_3675

DED:	DHBDCA_p19

DEC:

DCF50_p80

DRS:	DEHRE_00260 DEHRE_04865

DRM:

Dred_0739

DRU:	Desru_0248

DAE:

Dtox_0601

DKU:	Desku_2595

DAU:

Daud_0170

DGI:	Desgi_1712 Desgi_2669

HCV:	FTV88_2325(ablB) FTV88_2886

AWO:	Awo_c03840

ALKA:

J0B03_04700(ablB)

ACAE:

HYG86_09545(ablB)

ANV:	RBQ60_04810(ablB)

CLE:	Clole_3466

CBAR:

PATL70BA_2535(ablB) PATL70BA_2912(ablB)

AMT:

Amet_3657

TEB:	T8CH_0439(ablB)

EAC:	EAL2_808p00700(yodP)

NCD:	ACONDI_02810(yodP)

AAR:	Acear_1279

HHL:	Halha_1628

MALA:

NCTC10135_00980

ACIT:

HPK19_20025(ablB)

PBU:	L21SP3_01567

PBP:	STSP1_01892

PBAS:

SMSP2_01927

ALUS:

STSP2_00239

TAER:

GT409_01115(ablB)

SSM:	Spirs_3982

SGP:	SpiGrapes_0096

PSAC:

PSM36_1052

DORI:

FH5T_13975

DRC:	G0Q07_15175(ablB)

MCOS:

GM418_06350(ablB)

ASX:	CDL62_14110(ablB)

IRO:	RT717_02130(ablB)

FAX:	FUAX_54310

MARM:

YQ22_05335

MART:

BTR34_05575

MARB:

CJ263_11000(ablB)

MLIO:

NYZ99_16745(ablB)

CAO:	Celal_1713

FBE:	FF125_10005(ablB)

CPC:

Cpar_1398

CPB:	Cphamn1_1651

PVI:

Cvib_1365

PLT:

Plut_1575

PAA:

Paes_0800

PROC:

Ptc2401_01489

PRS:	B9H02_07280

PROS:

CHL67_07370(ablB)

DAP:	Dacet_0866

GTL:	EP073_02610(ablB)

MMP:	MMP0862(yodP)

MMQ:	MmarC5_0667

MMX:	MmarC6_1794

MMZ:	MmarC7_0107

MMD:

GYY_05005

MMAK:

MMKA1_09540

MMAO:

MMOS7_09330

MMAD:

MMJJ_01330(yodP)

MAE:

Maeo_0241

MVN:	Mevan_1222

MBA:	Mbar_A0671

MBY:	MSBRM_3253

MBW:	MSBRW_0332

MBAR:

MSBR2_3215

MAC:

MA_3978

MMA:

MM_0935

MMJ:	MSMAS_0371

MMAC:

MSMAC_0390

MVC:	MSVAZ_3255

MLS:	MSLAZ_0569

METM:

MSMTP_0454

MEF:	MSWH1_0411

MEQ:	MSWHS_0421

MSJ:	MSSAC_3713

MSZ:	MSSIH_3249

MSW:	MSSIT_3320

MHOR:

MSHOH_0462

MBU:

Mbur_0273

MELO:

J7W08_04635(ablB)

MMH:

Mmah_1438

MHAZ:

BHR79_06480

MPOT:

BKM01_02740

MZH:	Mzhil_1042

MPY:

Mpsy_1922

MZI:	HWN40_12605(ablB)

MMAV:

RE476_10915(ablB)

MSEB:

RE474_07490(ablB)

MRTJ:

KHC33_05755(ablB)

MLA:

Mlab_0344

MEM:	Memar_0216

MBG:	BN140_0213

MEMA:

MMAB1_0139 MMAB1_0278

MCHK:

MchiMG62_05130(yodP)

MSUM:

OH143_07830(ablB)

MRC:	R6Y96_01805(ablB) R6Y96_03020(ablB)

MPI:

Mpet_1465

MESB:

L1S32_06075(ablB)

MANQ:

L1994_09345(ablB)

MPD:

MCP_1918

MEZ:

Mtc_0927

RCI:

RRC392

PSYT:

DSAG12_02764

» show all

Reference

1 [PMID:14532061]

Authors

Pfluger K, Baumann S, Gottschalk G, Lin W, Santos H, Muller V

Title

Lysine-2,3-aminomutase and beta-lysine acetyltransferase genes of methanogenic archaea are salt induced and are essential for the biosynthesis of Nepsilon-acetyl-beta-lysine and growth at high salinity.

Journal

Appl Environ Microbiol 69:6047-55 (2003)
DOI:10.1128/AEM.69.10.6047-6055.2003

Sequence

[mma:MM_0935]

Reference

2 [PMID:21538109]

Authors

Muller S, Hoffmann T, Santos H, Saum SH, Bremer E, Muller V

Title

Bacterial abl-like genes: production of the archaeal osmolyte N(epsilon)-acetyl-beta-lysine by homologous overexpression of the yodP-kamA genes in Bacillus subtilis.

Journal

Appl Microbiol Biotechnol 91:689-97 (2011)
DOI:10.1007/s00253-011-3301-8

Sequence

[bsu:BSU19700]

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.264

IUBMB Enzyme Nomenclature:

2.3.1.264

ExPASy - ENZYME nomenclature database:

2.3.1.264

BRENDA, the Enzyme Database:

2.3.1.264

DBGET integrated database retrieval system