KEGG   ENZYME: 2.3.1.307
Entry
EC 2.3.1.307                Enzyme                                 
Name
6-diazo-5-oxo-L-norleucine Nalpha-acetyltranferase;
azpI (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:6-diazo-5-oxo-L-norleucine Nalpha-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + 6-diazo-5-oxo-L-norleucine = CoA + N-acetyl-6-diazo-5-oxo-L-norleucine [RN:R12932]
Reaction(KEGG)
R12932
Substrate
acetyl-CoA [CPD:C00024];
6-diazo-5-oxo-L-norleucine [CPD:C22429]
Product
CoA [CPD:C00010];
N-acetyl-6-diazo-5-oxo-L-norleucine [CPD:C22457]
Comment
The enzyme, characterized from the bacterium Streptacidiphilus griseoplanus, participates in the biosynthesis of the tripeptide alazopeptin.
History
EC 2.3.1.307 created 2021
Orthology
K25601  6-diazo-5-oxo-L-norleucine Nalpha-acetyltranferase
Genes
STRZOYE22_06070
Reference
1  [PMID:33624374]
  Authors
Kawai S, Sugaya Y, Hagihara R, Tomita H, Katsuyama Y, Ohnishi Y.
  Title
Complete Biosynthetic Pathway of Alazopeptin, a Tripeptide Consisting of Two Molecules of 6-Diazo-5-oxo-l-norleucine and One Molecule of Alanine.
  Journal
Angew Chem Int Ed Engl 60:10319-10325 (2021)
DOI:10.1002/anie.202100462
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.307
IUBMB Enzyme Nomenclature: 2.3.1.307
ExPASy - ENZYME nomenclature database: 2.3.1.307
BRENDA, the Enzyme Database: 2.3.1.307

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