KEGG ENZYME: 2.3.2.25

ENZYME: 2.3.2.25

Entry

EC 2.3.2.25                 Enzyme

Name

N-terminal E2 ubiquitin-conjugating enzyme;
Ube2w;
N-terminal ubiquitin-conjugating enzyme E2

Class

Transferases;
Acyltransferases;
Aminoacyltransferases

Sysname

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:acceptor protein ubiquitin ligase (peptide bond-forming)

Reaction(IUBMB)

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein] (overall reaction);
(1a) S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[N-terminal ubiquitin-conjugating enzyme]-L-cysteine;
(1b) S-ubiquitinyl-[N-terminal E2 ubiquitin-conjugating E2 enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine + N-ubiquitinyl-[acceptor protein]-N-terminal amino acid

Substrate

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine;
[acceptor protein]-N-terminal-amino acid;
[N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine;
S-ubiquitinyl-[N-terminal E2 ubiquitin-conjugating E2 enzyme]-L-cysteine

Product

[E1 ubiquitin-activating enzyme]-L-cysteine;
N-terminal-ubiquitinyl-[acceptor protein];
S-ubiquitinyl-[N-terminal ubiquitin-conjugating enzyme]-L-cysteine;
[N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine;
N-ubiquitinyl-[acceptor protein]-N-terminal amino acid

Comment

The enzyme ubiquitinylates the N-terminus of the acceptor protein. It is not reactive towards free lysine.

History

EC 2.3.2.25 created 2015

Orthology

K10688

ubiquitin-conjugating enzyme E2 W

Genes

HSA:	55284(UBE2W)

PTR:	464234(UBE2W)

PPS:	100968686(UBE2W)

GGO:	101125477(UBE2W)

PON:	100436654(UBE2W)

NLE:	100595750(UBE2W)

HMH:	116469733(UBE2W)

MCC:	696276(UBE2W)

MCF:	102114921(UBE2W)

MTHB:

126961703

MNI:	105483577(UBE2W)

CSAB:

103236976(UBE2W)

CATY:

105585273(UBE2W)

PANU:

101024590(UBE2W)

TGE:	112629750(UBE2W)

MLEU:

105541108(UBE2W)

RRO:	104664483(UBE2W)

RBB:	108515041(UBE2W)

TFN:	117079167(UBE2W)

PTEH:

111520972(UBE2W)

CANG:

105508320(UBE2W)

CJC:	100411128(UBE2W)

SBQ:	101049437(UBE2W)

CIMI:

108297524(UBE2W)

CSYR:

103273350(UBE2W)

MMUR:

105854801(UBE2W)

LCAT:

123644931(UBE2W) 123646218

PCOQ:

105817787 105825351(UBE2W)

OGA:	100965990(UBE2W)

MMU:	66799(Ube2w)

MCAL:

110301517(Ube2w)

MPAH:

110338770(Ube2w)

RNO:	100909445(Ube2w) 120099165(Ube2wl1)

MCOC:

116088204(Ube2w)

ANU:	117698603(Ube2w)

MUN:	132654751(Ube2w)

CGE:	100762319(Ube2w)

MAUA:

101835389(Ube2w)

PROB:

127231064(Ube2w)

PLEU:

114690122(Ube2w)

MORG:

121458295(Ube2w)

MFOT:

126501406

AAMP:

119826443(Ube2w)

NGI:	103746622(Ube2w)

HGL:	101724035(Ube2w)

CPOC:

100730250(Ube2w)

CCAN:

109692113(Ube2w)

DORD:

105994805(Ube2w)

DSP:	122108698(Ube2w)

PLOP:

125360514(Ube2w)

NCAR:

124986240

MMMA:

107142284(Ube2w)

OCU:	100340823 103347952

OPI:	101516997(UBE2W)

TUP:	102471306(UBE2W)

GVR:	103595488(UBE2W)

CFA:	486999(UBE2W)

CLUD:

112678618(UBE2W)

VVP:	112930294(UBE2W)

VLG:	121498777(UBE2W)

NPO:	129505290(UBE2W)

AML:	100470712(UBE2W)

UMR:	103681261(UBE2W)

UAH:	113253046(UBE2W)

UAR:	123800441(UBE2W)

ELK:

111156816

LLV:

125096943

MPUF:

101687734(UBE2W)

MNP:	132014089(UBE2W)

MLK:	131826702(UBE2W)

NVS:	122904516(UBE2W)

ORO:	101366102(UBE2W)

EJU:	114214179(UBE2W)

ZCA:	113931064(UBE2W)

MLX:	118014928(UBE2W) 118026245

NSU:	110579096(UBE2W) 123326503

LWW:	102731980(UBE2W)

FCA:	101100361(UBE2W)

PYU:	121038114(UBE2W)

PCOO:

112859244(UBE2W)

PBG:	122495494(UBE2W)

PVIV:

125156318(UBE2W)

LRUF:

124507723

PTG:	102963747(UBE2W)

PPAD:

109269355(UBE2W)

PUC:

125924608

AJU:

106968387

HHV:	120235864(UBE2W)

BTA:	613423(UBE2W)

BOM:	102267353(UBE2W)

BBUB:

102395826(UBE2W)

BBIS:

104993653(UBE2W)

CHX:	102182239(UBE2W)

OAS:	101107531(UBE2W)

BTAX:

128059396(UBE2W)

ODA:	120879029(UBE2W)

CCAD:

122450972(UBE2W)

MBEZ:

129560473(UBE2W)

SSC:	100152196(UBE2W)

CFR:	102522747(UBE2W)

CBAI:

105066158(UBE2W)

CDK:	105088551(UBE2W)

VPC:	102541357(UBE2W)

BACU:

103018032(UBE2W)

BMUS:

118883478(UBE2W)

LVE:	103070624(UBE2W)

OOR:	101269254(UBE2W)

DLE:	111185562(UBE2W)

PCAD:

102980709(UBE2W)

PSIU:

116742149(UBE2W)

NASI:

112413702(UBE2W)

ECB:	100051082(UBE2W)

EPZ:	103565253(UBE2W)

EAI:	106839238(UBE2W)

MYB:	102254981(UBE2W)

MYD:	102774697(UBE2W)

MMYO:

118670945(UBE2W)

MLF:	102435198(UBE2W)

PKL:	118718368(UBE2W)

EFUS:

103293939(UBE2W) 103302131 129149310

MNA:	107539537(UBE2W)

DRO:	112320748(UBE2W)

SHON:

118982591(UBE2W)

AJM:	119053414(UBE2W)

PDIC:

114501297(UBE2W)

PHAS:

123819125 123825781(UBE2W)

MMF:	118631422(UBE2W)

PPAM:

129065755 129088315(UBE2W)

HAI:	109383300(UBE2W)

RFQ:	117034057(UBE2W)

PALE:

102895199(UBE2W)

PGIG:

120585507(UBE2W)

PVP:	105296697(UBE2W)

RAY:	107515180(UBE2W)

MJV:	108408460(UBE2W)

TOD:	119240675(UBE2W)

SARA:

101542551(UBE2W)

SETR:

126020388(UBE2W) 126020972

LAV:	100655720(UBE2W)

TMU:

101359004

ETF:	101645992(UBE2W)

DNM:	101416427(UBE2W) 101443555

MDO:	100028124(UBE2W)

GAS:	123253300(UBE2W)

SHR:	100930487(UBE2W)

AFZ:

127543769

PCW:	110197268(UBE2W)

OAA:	100089545(UBE2W)

GGA:	420185(UBE2W)

PCOC:

116236261(UBE2W)

MGP:	100547672(UBE2W)

CJO:	107310283(UBE2W)

TPAI:

128090993(UBE2W)

LMUT:

125690385(UBE2W)

NMEL:

110393700(UBE2W)

APLA:

101792772(UBE2W)

ACYG:

106030591(UBE2W)

CATA:

118256319(UBE2W)

AFUL:

116486274(UBE2W)

TGU:	100227910(UBE2W)

LSR:	110470733(UBE2W)

SCAN:

103812906(UBE2W)

PMOA:

120499234(UBE2W)

OTC:	121340104(UBE2W)

PRUF:

121351911(UBE2W)

GFR:	102033188(UBE2W)

FAB:	101813609(UBE2W)

OMA:	130249400(UBE2W)

PHI:	102109159(UBE2W)

PMAJ:

107199696(UBE2W)

CCAE:

111924643(UBE2W)

CCW:	104692817(UBE2W)

CBRC:

103613567(UBE2W)

ETL:	114061629(UBE2W)

ZAB:	102067825(UBE2W)

ACHL:

103799869(UBE2W)

SVG:	106857439(UBE2W)

MMEA:

130572321(UBE2W)

HRT:	120754791(UBE2W)

FPG:	101913697(UBE2W)

FCH:	102051497(UBE2W)

CLV:	102090304(UBE2W)

EGZ:	104122379(UBE2W)

NNI:	104016171(UBE2W)

PCRI:

104025739(UBE2W)

PLET:

104617704(UBE2W)

EHS:	104510621(UBE2W)

PCAO:

104048374(UBE2W)

ACUN:

113476554(UBE2W)

TALA:

104361585(UBE2W)

PADL:

103926191(UBE2W)

AFOR:

103893510(UBE2W)

ACHC:

115340317(UBE2W)

HALD:

104322731(UBE2W)

HLE:	104837024(UBE2W)

AGEN:

126051243

GCL:

127013711

CCRI:

104156518(UBE2W)

CSTI:

104551952(UBE2W)

CMAC:

104475109(UBE2W)

MUI:	104541333(UBE2W)

BREG:

104636510(UBE2W)

FGA:	104071975(UBE2W)

GSTE:

104259908(UBE2W)

LDI:	104352159(UBE2W)

MNB:	103772227(UBE2W)

OHA:	104334840(UBE2W)

NNT:	104407923(UBE2W)

SHAB:

115613776(UBE2W)

DPUB:

104306625(UBE2W)

PGUU:

104457731(UBE2W)

ACAR:

104530145(UBE2W)

CPEA:

104386895(UBE2W)

AVIT:

104274267(UBE2W)

CVF:	104292498(UBE2W)

RTD:	128904912(UBE2W)

CUCA:

104068074(UBE2W)

TEO:	104371233(UBE2W)

BRHI:

104492020(UBE2W)

AAM:	106484622(UBE2W)

AROW:

112961273(UBE2W)

NPD:	112945725(UBE2W)

TGT:	104574185(UBE2W)

DNE:	112992225(UBE2W)

SCAM:

104153538(UBE2W)

ASN:	102384644(UBE2W)

AMJ:	102574930(UBE2W)

CPOO:

109319614(UBE2W)

GGN:	109304960(UBE2W)

PSS:	102443519(UBE2W)

CMY:	102941571(UBE2W)

CCAY:

125632561(UBE2W)

DCC:	119851778(UBE2W)

CPIC:

101950923(UBE2W)

TST:	117873584(UBE2W)

CABI:

116827328(UBE2W)

MRV:	120397853(UBE2W)

ACS:	100561037(ube2w)

ASAO:

132774918(UBE2W)

PVT:	110089643(UBE2W)

SUND:

121929559(UBE2W)

PBI:	103048188(UBE2W)

PMUR:

107297275(UBE2W)

CTIG:

120303003(UBE2W)

TSR:	106538603(UBE2W)

PGUT:

117672890(UBE2W)

APRI:

131195410(UBE2W)

PTEX:

113439974(UBE2W)

NSS:	113429125(UBE2W)

VKO:	123020414(UBE2W)

PMUA:

114600507(UBE2W)

PRAF:

128417349(UBE2W)

ZVI:	118090333(UBE2W)

HCG:	128323442(UBE2W)

GJA:	107114639(UBE2W)

STOW:

125439186(UBE2W)

EMC:	129333561(UBE2W)

XLA:	108695347(ube2w.S) 108705626 121394743

XTR:	548886(ube2w)

NPR:	108797560(UBE2W)

RTEM:

120941150(UBE2W)

BBUF:

121001453(UBE2W)

BGAR:

122938839(UBE2W)

MUO:	115478298(UBE2W)

GSH:	117355167(UBE2W)

DRE:	553013(ube2wa) 692325(ube2wb)

SRX:	107725703 107732582 107751351 107754202

SANH:

107657829 107664038 107686032 107691409

SGH:	107550716 107585923 107589971

CCAR:

109062478 109077625 109085092 109105955

CAUA:

113042320 113045543 113045584 113066087 113117746 113117768

CGIB:

127946585 127950769 128013426 128029724

PTET:

122329409(ube2wb) 122355470(ube2wa)

LROH:

127154410(ube2wa) 127155875(ube2wb)

OMC:	131524313(ube2wa) 131533507(ube2wb)

PPRM:

120475897(ube2wb) 120482502(ube2wa)

RKG:	130087693(ube2wb) 130101673(ube2wa)

MAMB:

125251079(ube2wa) 125257534(ube2wb)

CIDE:

127501004 127506392

MASI:

127431434 127434332 127440501 127442258

TROS:

130547422(ube2wb) 130554013(ube2wa)

TDW:	130413382(ube2wb) 130417796(ube2wa)

MANU:

129425605(ube2wb) 129442142(ube2wa)

IPU:	108256706(ube2wb) 108280505(ube2wa)

IFU:	128599887(ube2wb) 128624397(ube2wa)

PHYP:

113541067(ube2w) 113543281

SMEO:

124375577(ube2wb) 124403012(ube2wa)

TFD:	113636896 113636898 113636899 113636900 113640296(ube2wa) 113660621(ube2wb) 125139955

TVC:	132840405(ube2wb) 132842826 132842887 132842900 132842908 132842916 132842921 132847794(ube2wa) 132856680 132857787

AMEX:

103024049 103034207

CMAO:

118797089(ube2w) 118799064(flj11011l)

EEE:	113578069 113586087

CHAR:

105890219(ube2wb)

TRU:	101065623(ube2w)

TFS:

130514194

TNG:	GSTEN00015564G001

LCO:	104921310(ube2w)

NCC:	104967921(ube2w)

TBEN:

117484053(flj11011l)

CGOB:

115025482(ube2w)

PGEO:

117465717(flj11011l)

GACU:

117561437

EMAC:

134884138(ube2wb)

ELY:	117264823(flj11011l)

EFO:

125881531

PLEP:

121960699

SLUC:

116037939(flj11011l)

ECRA:

117937925(flj11011l)

ESP:	116672648(ube2w)

PFLV:

114549410(ube2w)

GAT:	120811624(ube2wb)

PPUG:

119198523(flj11011l)

AFB:	129110501(ube2wb)

CLUM:

117749417(flj11011l)

PSWI:

130205918(ube2wb)

MSAM:

119909158(flj11011l)

SCHU:

122866775(ube2wb)

CUD:	121527416(ube2wb)

ALAT:

119008846(flj11011l)

MZE:	101487815(ube2w)

ONL:	100707173(ube2w)

OAU:	116328284(ube2wb)

OLA:	101168999(ube2w)

OML:	112151382(flj11011l)

CSAI:

133423303(ube2wb)

XMA:	102224996(ube2w)

XCO:	114136823(ube2w)

XHE:	116711898(ube2w)

PRET:

103456677(ube2w)

PFOR:

103139785(ube2w)

PLAI:

106937249(ube2w)

PMEI:

106931890(ube2w)

GAF:	122824272(ube2wb)

PPRL:

129364958(ube2wb)

CVG:	107097763(ube2w)

CTUL:

119772309(flj11011l)

GMU:	124858407(ube2wb)

NFU:	107382925(ube2w)

KMR:	108230264(flj11011l)

ALIM:

106513484(ube2w)

NWH:	119426670(ube2wb)

AOCE:

111572415(ube2w)

MCEP:

124995513(ube2wb)

CSEM:

103377002(ube2w)

POV:	109629453(ube2w)

SSEN:

122778882(ube2wb)

HHIP:

117753676(flj11011l)

HSP:	118098433(ube2wb)

SMAU:

118291148(ube2wb)

LCF:	108881822(ube2wb)

SDU:	111221031(ube2w)

SLAL:

111662942(ube2w)

XGL:	120790016(ube2wb)

HCQ:	109517000(ube2w)

SSCV:

125985987

SBIA:

133492867(ube2wb)

PEE:	133396388(ube2wb)

PTAO:

133470582(ube2wb)

BPEC:

110160941(ube2w)

MALB:

109960119(ube2w)

BSPL:

114853170(ube2wb)

SJO:	128382671(ube2wb)

SASA:

106579737(ube2w) 106591739

STRU:

115149042(ube2w) 115195325

OTW:	112236392(ube2wb) 112240730

OMY:	100305246(ube2w) 110535176(flj11011l)

OGO:	123991444(ube2wb) 124039447

ONE:	115126954(ube2w)

OKI:	109876027(ube2w)

OKE:

118376785

SALP:

112072669(ube2w)

SNH:	120027615(flj11011l)

CCLU:

121555304 121569964(ube2wb)

ELS:	105019654(ube2w)

SFM:	108935406(ube2w)

PKI:	111834906(ube2w)

AANG:

118225846(flj11011l) 118234563(ube2w)

LOC:	102687230(ube2w)

PSPA:

121307987 121313409 121314357

ARUT:

117400400 117435414(flj11011l)

PSEX:

120530184(ube2wb)

LCM:	102361547(UBE2W)

CMK:	103174572(ube2wb)

RTP:

109929883

CPLA:

122549402(ube2wb)

HOC:	132811205(ube2wb)

LERI:

129696511(ube2wb)

PMRN:

116942613(UBE2W)

LRJ:	133349143(UBE2W)

BFO:

118409414

BBEL:

109485907

CIN:

100177184

SCLV:

120338700

SPU:

582071

LPIC:

129279850

APLC:

110988165

AJC:

117122245

SKO:

100371975

DME:	Dmel_CG7220(CG7220)

DER:

6547556

DSE:

6608553

DSI:	Dsimw501_GD10753(Dsim_GD10753)

DYA:	Dyak_GE12835

DAN:

6496610

DSR:

110189218

DPO:

4805323

DPE:

6592511

DMN:	108159623 117185800

DWI:

6639848

DGR:

6559811

DMO:	Dmoj_GI19345

DAZ:

108616935

DNV:

108654436

DHE:

111593303

DVI:

6626551

CCAT:

101459993

BOD:

106614780

BDR:

105229661

RZE:	108358516 108382106

AOQ:

129243864

TDA:	119684153 119685877

MDE:

101889802

SCAC:

106080679 106080683 106080694

LCQ:

111681658

LSQ:

119607760

GFS:

119636248

ECOE:

129949659

CLON:

129605724

HIS:

119647269

AGA:

1276032

ACOZ:

120949368

AARA:

120893456

AMER:

121593562

ASTE:

118509767

AFUN:

125768925

AMOU:

128301024

AALI:

118465720

AAG:

5570741

AALB:

109417952 109426840

CQU:	CpipJ_CPIJ009955 CpipJ_CPIJ015851

CPII:

120421534

CNS:

116345633

BCOO:

119074133

AME:

409100

ACER:

108001832

ALAB:

122716743

ADR:

102676020

AFLR:

100863020

BIM:

100743714

BBIF:

117209133

BVK:

117233901

BVAN:

117160766

BTER:

100648710

BAFF:

126914925

BPYO:

122569439

BPAS:

132904462

FVI:

122536803

CCAL:

108632398

OBB:

114871189

OLG:

117605430

MGEN:

117228763

NMEA:

116424227

CGIG:

122395103

SOC:

105193427

MPHA:

105834299

AEC:

105145047

ACEP:

105619446

PBAR:

105430277

VEM:

105565018

HST:

105189835

DQU:

106749409

CFO:

105255644

FEX:	115233842 115233843 115233845

LHU:

105678064

PGC:

109856413

OBO:

105279036

PCF:

106791725

PFUC:

122518763

VPS:

122626953

VCRB:

124431501

VVE:

124957855

LHT:

122500458

LBD:

127282799

MDL:

103573819

CGLO:

123265461

FAS:

105267221

DAM:

107040825

AGIF:

122850199

CINS:

118069842

VCAN:

122419038

CCIN:

107267079

DSM:

124413558

NPT:

124222060

NFB:

124185350

NLO:

107226874

NVG:

124307682

AROA:

105684105

TCA:

663661

DPA:

109544758

SOY:

115882223

AGRG:

126747658

ATD:

109603785

CSET:

123322494

AGB:

108916392

NVL:

108563601

APLN:

108743774

PPYR:

116181473

OTU:

111416501

BMOR:

101742775

BMAN:

114242203

MSEX:

115449547

BANY:

112051352

MJU:

123868376

NIQ:

126774354

VCD:

124536115

MCIX:

123659955

PMAC:

106709150

PPOT:

106101709

PXU:

106121313

PRAP:

111003478

PBX:

123714813

PNAP:

125057107

ZCE:

119828159

CCRC:

123694184

LSIN:

126965517

AAGE:

121738601

HAW:

110375582

HZE:

124635003

TNL:

113498056

SLIU:

111358831

OFU:	114350754 114350917

PXY:	105385283 105396699

PGW:

126372568

CFEL:

113386573

API:	100161121 100165321 100167313 100570490 100575714

DNX:	107164100 107164355

AGS:	114128758 114128759 114129266

RMD:	113556214 113556995

ACOO:

126834790

DVT:

126903475

BTAB:

109039258

DCI:

103509952

CLEC:

106663108

HHAL:

106682788

NLU:

111059848

MQU:	129002127 129004294

PHU:	Phum_PHUM521050

FOC:

113203704

TPAL:

117650237

ZNE:

110831634

CSEC:

111874785

SGRE:

126356299

BROR:

134541341

IEL:

124164123

FCD:

110842473

DPX:	DAPPUDRAFT_211776

DMK:

116936435

DPZ:

124343805

PVM:

113800412

PJA:

122262849

PCHN:

125033425

PMOO:

119578131

HAME:

121864198

PCLA:

123775330

CQD:	128691035 128706075

PTRU:

123506091

ESN:

127005237

MNZ:

135215102

EAF:

111699876

LSM:

121130567

TCF:

131885825

PPOI:

119105914 119106408

ISC:

8031048

DSV:

119431404

RSAN:

119371802

RMP:

119163295

VDE:

111250165

VJA:

111260926

TUT:

107366439

DPTE:

113799677

DFR:

124492709

CSCU:

111616631 111629160

PTEP:

107438487

ABRU:

129971162

UDV:	129233177 129233271

LPOL:

106462144 106473838

PMEO:

129582156

CEL:	CELE_Y54E5B.4(ubc-16)

CBR:	CBG_19703(Cbr-ubc-16)

CRQ:	GCK72_001446

BMY:	BM_BM6791(Bma-ubc-16)

LOA:	LOAG_02096

TSP:

Tsp_07604

HRO:	HELRODRAFT_185420

LGI:	LOTGIDRAFT_152035

PVUL:

130012377

PCAN:

112574400

BGT:

106066127

GAE:

121375007

HRF:

124133280

HRJ:

124253700

CRG:

105319798

CVN:	111118898 111118984

CANU:

128166383

OED:

125668447

MYI:

110457543

PMAX:

117325297

MCAF:

127712718

MMER:

123524913

RPHI:

132730351

DPOL:

127862211

OBI:

106871524

OSN:

115222165

LAK:

106169942

NVE:

5503004

ATEN:

116297191 116298845

ADF:

107341212

AMIL:

114963298

PDAM:

113670640

SPIS:

111332059

DGT:

114528850

XEN:

124442325

HMG:

100208384

HSY:

130614872

TAD:	TRIADDRAFT_50463

AQU:

100635218

ATH:	AT1G45050(ATUBC2-1) AT1G75440(UBC16) AT4G36410(UBC17) AT5G42990(UBC18)

ALY:	110230768 9299780 9303090

CRB:	17874804 17879861 17894176

CSAT:

104702291 104713197 104716493 104721132 104725173 104751418 104760657 104771441 104784521 109124420

EUS:	EUTSA_v10003273mg EUTSA_v10011837mg EUTSA_v10019254mg EUTSA_v10026441mg

BRP:	103831997 103839263 103854364 103862470 103868454 103868723

BNA:	106369853 106370036 106374319 106397105 106405958 106406056 106407062 106415585 106447063 106451961 106453810 111209356 125594216

BOE:	106296583 106298499 106300566 106301778 106316257 106344066

RSZ:	108817876 108826201 108840445 108856813 130504500

THJ:	104804248 104809296 104813814 104814151 104822837

CPAP:

110822177 110822179

CIT:	102622195 102628324

CIC:	CICLE_v10002737mg CICLE_v10026664mg

PVY:	116118939 116127481 116127567

MINC:

123198630 123202631 123219830 123229747

TCC:	18591456 18610846

GRA:	105763248 105770470 105784905 105787505

GHI:	107905467 107909427 107918005 107934253 107935354 107936522 107945821 107957952

GAB:	108454520 108470168 108477213 108480366

HSYR:

120126460 120126904 120130636 120152319 120156794 120160861 120183793 120195286 120198396

DZI:	111292136 111300066 111312757 111315326 111317215

EGR:

104419696

GMX:	100305572 100785024

GSJ:

114373798

PVU:	PHAVU_002G112300g

VRA:

106776419

VAR:

108335984

VUN:

114174112

VUM:

124834820

CCAJ:

109799881

APRC:

113868578

MTR:

11412171

TPRA:

123910395 123920659

CAM:	101489578 101511491

ADU:

107488018

AIP:

107642925

LANG:

109332035 109332931 109348712

PCIN:

129311180

QSA:	O6P43_024823 O6P43_033650

FVE:	101309868 101311070

RCN:	112174697 112189896

PPER:

18769569 18788189

PMUM:

103321324 103340151

PAVI:

110771545 110774227

PDUL:

117615296 117615297 117635636

MDM:	103400842 103415945 103428606 103450430

MSYL:

126590645 126602547 126604234 126631120

PXB:	103928464 103937826

ZJU:	107424575 107435482

MNT:	21396425 21404742

CSAV:

115714654

CSV:

101202936

CMO:

103493218

BHJ:

120069953

MCHA:

111008493

CMAX:

111481748 111483386

CMOS:

111436055 111447396

CPEP:

111778286 111810876

RCU:	8275785 8279121

JCU:

105633856

HBR:	110632616 110639582 110668541

MESC:

110601618 110609601 110614461

POP:	18099237 7471931 7477635 7480148

PEU:	105126645 105128562 105128788 105142747

PALZ:

118030010 118052774 118062102 118063088

JRE:	108991400 108992031 108992052

CILL:

122314836 122315415 122315416

CAVE:

132168730 132190438

QSU:	112000857 112015132

QLO:	115950665 115963937 115974408

TWL:	119997057 120000486 120008616 120015148 120016796

VVI:	100260813 100262599

VRI:	117907859 117913414

SLY:	101243704 101245015

SPEN:

107008819 107015904 114076929

SOT:	102597478 102605143

SSTN:

125849559 125855071

SDUL:

129873883 129904187

CANN:

107860017 107866954

LBB:	132622766 132628064

NTA:	107759180 107769767 107776491 107796639 107799066 107824081 107824880

NSY:	104213286 104222292 104227774

NTO:	104095521 104099541 104103454

NAU:	109210585 109215162 109241316

INI:	109170059 109172714

ITR:	116000987 116018744

SIND:

105159308 105166086

OEU:	111374534 111376259 111388497 111401306

EGT:	105959542 105962982

SSPL:

121756294 121758839 121802639 121804424 121808598 121810085

SMIL:

130986596 130986600

SHIS:

125198674 125218550

APAN:

127246889 127256920

HAN:	110878865 110879588 110889468 110909006

ECAD:

122587287 122589715 122603947

LSV:	111881613 111913121 111913332

CCAV:

112510107 112515790 112516026

DCR:	108211081 108216234 108224932

CSIN:

114255974 114292554 114310466 114315268

RVL:	131330980 131332342

AEW:	130758524 130783684 130785405 130786801 130787850

BVG:	104889212 104895089

SOE:	110790575 110798889

CQI:	110682552 110685857 110723285

ATRI:

130808140 130820909

MOF:	131147025 131163092

NNU:	104595596 104610559

MING:

122073889 122091038

TSS:	122658486 122661488

PSOM:

113288711 113288754 113349812 113357704

OSA:	4333728 4352894

DOSA:

Os03t0681400-01(Os03g0681400) Os12t0636800-01(Os12g0636800)

OBR:	102713505 102718820

OGL:	127758139 127766205

BDI:	100831205 100833131

ATS:	109759242 109762224

TDC:	119287069 119294650 119294651 119298748 119306984

TAES:

123087280 123089894 123090677 123095689 123101947 123110067 123119069

TUA:

125530452

LPER:

127293453 127299029

LRD:	124651846 124651847 124654593 124703843

SBI:	8054171 8065249

ZMA:	100193523 100272309 100280549 100282569

SITA:

101757555 101785896

SVS:	117840782 117848108

PVIR:

120648336 120667087 120691040 120700257

PHAI:

112874996 112887215

PDA:	103710168 103712016 103723967

EGU:	105034324 105042247 105053327 105053456

MUS:	103983128 103989436 103997582 103998935

ZOF:	121980994 121984881 122001532 122005829 122010426 122017018 122050914 122055492

DCT:	110095511 110103836 110110478

PEQ:	110024456 110029123

AOF:	109834079 109835275 109849453

MSIN:

131232655 131248892

NCOL:

116256377 116266408

ATR:

18429279

SMO:	SELMODRAFT_159187(UBC15-2) SELMODRAFT_172555(UBC16-2) SELMODRAFT_268066(UBC16-1) SELMODRAFT_270987(UBC15-1)

PPP:	112292566 112294104

CRE:	CHLRE_02g141450v5

VCN:	VOLCADRAFT_95153

CSL:	COCSUDRAFT_67139

APRO:

F751_3522

CME:	CYME_CMQ038C

GSL:	Gasu_43090

CCP:	CHC_T00006794001

PPA:	PAS_FragB_0055

PIC:	PICST_36882

PGU:	PGUG_04836

SPAA:

SPAPADRAFT_60051

LEL:	PVL30_003182

CAL:	CAALFM_C210580WA(UBC15)

CTP:	CTRG_01929

COT:	CORT_0C07320

CDU:	CD36_24750

CTEN:

CANTEDRAFT_97645

YLI:	YALI0F31955g

CLU:	CLUG_00202

CLUS:

A9F13_29g00110

PKZ:	C5L36_0B12860

BBRX:

BRETT_001916

OPA:	HPODL_01966

NCR:

NCU09122

NTE:	NEUTE1DRAFT90783(NEUTE1DRAFT_90783)

SMP:	SMAC_04618

PAN:	PODANSg5636

PBEL:

QC761_109400

PPSD:

QC762_109400

PPSP:

QC763_109400

PPSA:

QC764_109400

TTT:	THITE_2121543

MTM:	MYCTH_2074876

MGR:

MGG_09913

PPEI:

PpBr36_07687

PGRI:

PgNI_06322

TMN:	UCRPA7_6530

SSCK:

SPSK_09847

FGR:	FGSG_06877

FPU:	FPSE_11787

FPOA:

FPOAC1_010622

FVN:	FVRRES_11623

FVR:	FVEG_05108

FOX:	FOXG_01947

NHE:	NECHADRAFT_79102

FFC:	NCS54_00563800

FKR:	NCS57_00601700

FMU:	J7337_002640

TRE:	TRIREDRAFT_121048

TRR:	M419DRAFT_97134

MAW:

MAC_00992

MAJ:

MAA_05741

PCHM:

VFPPC_02977

CMT:

CCM_02340

AMUS:

LMH87_003835

PTKZ:

JDV02_001087

VAL:	VDBG_04934

VDA:	VDAG_04475

CFJ:	CFIO01_13389

CLUP:

CLUP02_05337

CHIG:

CH63R_00495

SAPO:

SAPIO_CDS3634

PFY:	PFICI_00886

SSL:	SS1G_10020

BFU:	BCIN_07g04720

MBE:

MBM_02438

PSCO:

LY89DRAFT_575622

GLZ:	GLAREA_00811

ANI:	ANIA_02413

AFM:	AFUA_2G13690

ACT:	ACLA_073940

NFI:	NFIA_088880

AOR:	AO090026000230

ANG:	An02g05480

AFV:	AFLA_006069

ALUC:

AKAW2_21164S

ACHE:

ACHE_50796A

APUU:

APUU_20811S

PCS:	N7525_001370

PDP:	PDIP_78920

TMF:	EYB26_001976

TRG:	TRUGW13939_05327

CIM:	CIMG_04632

CPW:	CPC735_071750

URE:	UREG_01831

PBL:	PAAG_05736

PBN:	PADG_07653

ABE:

ARB_04411

TVE:

TRV_06810

AJE:	HCAG_04622

BGH:	BDBG_04592

PTE:

PTT_07968

BZE:	COCCADRAFT_33381

BSC:	COCSADRAFT_38137

BOR:	COCMIDRAFT_24496

AALT:

CC77DRAFT_1019632

ARAB:

EKO05_0001959

PFJ:	MYCFIDRAFT_142521

CBET:

CB0940_03994

BCOM:

BAUCODRAFT_149008

NPA:	UCRNP2_2702

TML:	GSTUM_00008760001

CNE:

CNE04250

CNB:

CNBE4240

CNG:	CNAG_02112

CGI:	CGB_E5520C

CDEU:

CNBG_5261

TMS:	TREMEDRAFT_64580

CCAC:

CcaHIS019_0210930(CcaverHIS019_0210930)

TVS:	TRAVEDRAFT_26117

DSQ:	DICSQDRAFT_184257

PCO:	PHACADRAFT_246228

SHS:	STEHIDRAFT_88837

HIR:	HETIRDRAFT_145590(ubc2)

ADL:	AURDEDRAFT_109528

FME:	FOMMEDRAFT_122237

GTR:	GLOTRDRAFT_113631

RSX:	RhiXN_00991

LBC:	LACBIDRAFT_242784

CCI:	CC1G_03732

ABP:	AGABI1DRAFT81426(AGABI1DRAFT_81426)

ABV:	AGABI2DRAFT189796(AGABI2DRAFT_189796)

PCUB:

JR316_0000771

MPR:	MPER_02097

MRR:

Moror_347

E1B28_009818

SCM:	SCHCO_02609213(SCHCODRAFT_02609213)

CPUT:

CONPUDRAFT_78705

SLA:	SERLADRAFT_401900

WSE:	WALSEDRAFT_34288

WIC:	J056_002619

UMA:	UMAG_03443

PFP:	PFL1_02219

SGRA:

EX895_006416

PGR:	PGTG_00822

PTRC:

PtA15_17A312

PSTR:

Pst134EA_030581

MLR:	MELLADRAFT_110721

SRE:	PTSG_00932

DDI:	DDB_G0268938(ube2w)

DPP:	DICPUDRAFT_157952

DFA:	DFA_07886(ube2w)

PFA:	PF3D7_1412900.1

PFH:	PFHG_05099

PGAB:

PGSY75_1412900

PYO:	PY17X_1032100

PCB:	PCHAS_1030500

PBE:	PBANKA_1029700

PVV:	PVVCY_1003510

PKN:	PKNH_1345400

PVX:	PVX_085805

PCY:	PCYB_134380

PMAL:

PMUG01_13045500

PREL:

PRELSG_1338200

TET:	TTHERM_00285290

PTM:	GSPATT00016175001 GSPATT00030369001 GSPATT00032900001 GSPATT00034321001

SMIN:

v1.2.018903.t1(symbB.v1.2.018903.t1)

EHX:	EMIHUDRAFT_452424

GTT:	GUITHDRAFT_156286

NGR:	NAEGRDRAFT_44833

» show all

Reference

1 [PMID:9774340]

Authors

Breitschopf K, Bengal E, Ziv T, Admon A, Ciechanover A

Title

A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein.

Journal

EMBO J 17:5964-73 (1998)
DOI:10.1093/emboj/17.20.5964

Reference

2 [PMID:23560854]

Authors

Tatham MH, Plechanovova A, Jaffray EG, Salmen H, Hay RT

Title

Ube2W conjugates ubiquitin to alpha-amino groups of protein N-termini.

Journal

Biochem J 453:137-45 (2013)
DOI:10.1042/BJ20130244

Sequence

[hsa:55284]

Reference

3 [PMID:23696636]

Authors

Scaglione KM, Basrur V, Ashraf NS, Konen JR, Elenitoba-Johnson KS, Todi SV, Paulson HL

Title

The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.

Journal

J Biol Chem 288:18784-8 (2013)
DOI:10.1074/jbc.C113.477596

Sequence

[hsa:55284]

Other DBs

ExplorEnz - The Enzyme Database:

2.3.2.25

IUBMB Enzyme Nomenclature:

2.3.2.25

ExPASy - ENZYME nomenclature database:

2.3.2.25

BRENDA, the Enzyme Database:

2.3.2.25

All links

Gene (3128)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1288)   
   KEGG MGENES (121)   
   RefGene (1718)   
Protein sequence (1643)   
   UniProt (1622)   
   SWISS-PROT (9)   
   RefSeq(pep) (12)   
DNA sequence (36)   
   RefSeq(nuc) (13)   
   GenBank (12)   
   EMBL (11)   
Protein domain (3)   
   InterPro (3)   
All databases (4810)   

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