Entry
Name
sucrose synthase;
UDPglucose-fructose glucosyltransferase;
sucrose synthetase;
sucrose-UDP glucosyltransferase;
sucrose-uridine diphosphate glucosyltransferase;
uridine diphosphoglucose-fructose glucosyltransferase;
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
NDP-alpha-D-glucose:D-fructose 2-alpha-D-glucosyltransferase (configuration-retaining)
Reaction(IUBMB)
NDP-alpha-D-glucose + D-fructose = NDP + sucrose [RN:
R07256 ]
Reaction(KEGG)
Substrate
Product
Comment
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
History
EC 2.4.1.13 created 1961, modified 2003
Pathway
ec00500 Starch and sucrose metabolism
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
ATH : AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)
ALY : 9301791 9304569 9308917 9310083 9311669 9324989
CRB : 17877054 17877643 17881746 17882355 17887544 17895033
CSAT : 104702036 104706429 104707872 104712951 104713942 104719340 104723601 104724082 104725413 104732612 104736154 104737553 104751189 104763273 104770460
EUS : EUTSA_v10003667mg EUTSA_v10012719mg EUTSA_v10018094mg EUTSA_v10027639mg EUTSA_v10028435mg
BRP : 103830752 103831821 103836763 103845641 103856465 103868315 103875021
BNA : 106345241 106348876 106354279 106365510 106371709 106386990 106391382 106402327 106406752 106407384 106434916 106451551 111210221 111211726 125595989 125603413
BOE : 106296231 106296386 106296521 106304017 106318311 106319066 106336052
RSZ : 108814119 108814255 108817509 108823863 108828189 108847491 108852315 130503214 130504406
THJ : 104799606 104805659 104810983 104812185 104825963 104827331
CPAP : 110807262 110812012 110815045 110825587
CIT : 102615040 102615807 102616003 102626007 102627856 102629055
CIC : CICLE_v10004341mg CICLE_v10007483mg CICLE_v10010343mg CICLE_v10011062mg CICLE_v10018889mg
PVY : 116106406 116120517 116121153 116135571 116142065 116146707
MINC : 123194710 123200616 123204669 123206792 123216592 123219960 123226044
TCC : 18588220 18588224 18601247 18603545 18604515 18613599
GRA : 105767999 105773086 105774032 105782817 105788781 105791444 105797719 105802152
GHI : 107893375 107899372 107901027 107901030 107907080 107910106 107924200 107926875 107929861 107937480 107942366 107953943 107958826 107962183 121212571
GAB : 108463993 108466049 108466051 108468821 108469697 108479546 108481007 108489178
HSYR : 120113930 120132153 120135999 120153557 120154030 120157047 120161678 120164684 120166598 120181470 120182243 120183607 120199634
DZI : 111285632 111286797 111289721 111299212 111303031 111305045 111314106 111314681
EGR : 104422202 104425866 104426782 104436385 104437963 104437966 104440058 104440059 104440060 104449054 104456736
GMX : 100783965 100788584 100788717 100792097 100793371 100802045 100805344 100806761 100808482 100809674 100819730 547508(SS)
GSJ : 114367734 114380841 114381373 114383518 114386366 114387590 114390127 114394232 114397685 114398239 114407393 114425696
PVU : PHAVU_001G209600g PHAVU_003G127500g PHAVU_004G142800g PHAVU_006G087300g PHAVU_008G241300g PHAVU_009G223800g PHAVU_009G250800g
VRA : 106757631 106762013 106762931 106768289 106774050 106775028
VAR : 108328968 108331593 108336175 108341918 108343245 108343673
VUN : 114162257 114162957 114178360 114180338 114185026 114186592 114193263
VUM : 124821239 124828545 124830145 124834271 124842285 124842733 124842736
CCAJ : 109800571 109803338 109807766 109809843 109812209 109814177 109819188
APRC : 113846477 113848337 113849368 113852999 113853320 113863028 113866733
MTR : 11414896 11419005 11433144 11446733 25486575 25499615
TPRA : 123882187 123891152 123907155 123910155 123916258 123920206 123920691
CAM : 101490898 101491581 101494314 101509229 101511421 101514095 101514674
PSAT : 127084279 127091212 127118331 127132648 127133097 127136197 127138723
VVO : 131594970 131610820 131620908 131622082 131628295 131630023 131638133 131638405 131639843 131642242 131643942 131662093
LJA : Lj0g3v0242009.1(Lj0g3v0242009.1) Lj1g3v4875640.1(Lj1g3v4875640.1) Lj1g3v4875640.2(Lj1g3v4875640.2) Lj2g3v2507780.1(Lj2g3v2507780.1) Lj3g3v1238910.1(Lj3g3v1238910.1) Lj4g3v2215210.1(Lj4g3v2215210.1) Lj6g3v1162830.1(Lj6g3v1162830.1) Lj6g3v1162830.2(Lj6g3v1162830.2) Lj6g3v1468270.2(Lj6g3v1468270.2)
ADU : 107479418 107481015 107490724 107492465 107496082
AIP : 107630591 107631415 107638421 107644054 107645662
AHF : 112695778 112696276 112733763 112738386 112740751 112750827 112756421 112790604 112791679 112802440
LANG : 109326830 109327632 109327633 109330009 109335230 109347960 109356508 109357071 109358788 109362433
PCIN : 129296330 129303231 129305712 129308377 129314448 129317877
QSA : O6P43_002617 O6P43_005274 O6P43_007201 O6P43_010804 O6P43_010806 O6P43_014227 O6P43_020529 O6P43_021780 O6P43_022532 O6P43_034209
FVE : 101292831 101298794 101299138 101306372 101309357 101313949
RCN : 112169184 112176664 112186368 112188591 112194953 112198236
PPER : 18767223 18770262 18777229 18781998 18790747 18791635
PMUM : 103323061 103327363 103333990 103338879 103340632 103343570
PAVI : 110745885 110748673 110749140 110749336 110750201 110750203 110765091
PDUL : 117616724 117616772 117620602 117624116 117625045 117628670 117636070 117636939
MDM : 103400901 103409880 103414597 103414598 103426254 103444250 103449164(SS) 103453958 103455689
MSYL : 126591295 126596199 126598550 126603861 126606390 126608024 126608040 126612519 126625034 126634136
PXB : 103933877 103935319 103935320 103939687 103940505 103940506 103943695 103946870 103948072 103950289 103956794 103956799 103959924 103959925 103967199
ZJU : 107406759 107416188 107419708 107426335 107433125
MNT : 21386815 21391172 21394396 21402491 21407811
CSAV : 115705430 115705483 115714498 115721870 115722614
CSV : 101203847 101211461 101213767 101216865
CMO : 103483781 103492399 103494755 103501373
BHJ : 120067696 120070539 120084220 120091208
MCHA : 111008572 111011768 111016476 111022442
CMAX : 111466367 111484831 111487031 111489205 111492795 111493280 111495515
CMOS : 111431589 111438640 111444757 111452459 111452903 111461509 111462013
CPEP : 111779778 111782779 111787525 111788999 111793310 111803958 111809443
RCU : 8259046 8259900 8275091 8278014 8278767
JCU : 105636138 105636179 105636921 105642561 105643468
HBR : 110636873 110637152 110637531 110638834 110644580 110653739 110659273
MESC : 110602887 110603638 110610584 110611700 110612799 110617712 110630948
POP : 18100284 18105619 7454032 7461280 7478850 7487419 7490531
PEU : 105110371 105112458 105115703 105135236 105136321 105139213 105142024
PALZ : 118030349 118031772 118044357 118046817 118048507 118056701 118057271
JRE : 108981886 108988247 108990945 108993242 108994129 108994212
CILL : 122296245 122299226 122302940 122304228 122306732 122307734 122314839
CAVE : 132164910 132172810 132181029 132183910
QSU : 111984605 111984866 111993270 112018943 112019923 112020114 112028228
QLO : 115962644 115968544 115969012 115969119 115970897 115976201 115995023
TWL : 119982744 119986680 119996757 120004142 120005735 120012929
VVI : 100243135 100249279 100252799 100266759 100267606
VRI : 117912209 117914836 117917576 117924712 117934381
SLY : 101253025(SUS4) 101255377 101266782 101267720 543731(sus3) 543961
SPEN : 107005525 107010996 107012422 107026306 107026596 107029484
SOT : 102577575 102577594(SS16) 102577712 102582945 102586510 102588355
SSTN : 125846239 125852920 125860306 125861222 125875563 125876400
SDUL : 129870083 129872965 129882963 129882964 129892571 129892575 129894276
CANN : 107840883 107859646 107862814 107864054 107877893
LBB : 132608847 132617183 132618706 132623550 132632379 132636943
NTA : 107766404 107769655 107771392 107775584 107775654 107783276 107786515 107789130 107789131(SUSY) 107789475 107796229 107804066 107830010
NSY : 104212806 104220987 104236866 104239665 104243818 104246100
NTO : 104087069 104096609 104108826 104116253 104116323 104116324
NAU : 109206481 109208908 109214879 109226534 109228646 109242798
INI : 109160151 109167470 109170760 109172636 109187875 109190716 109192510
ITR : 115996551 116009826 116009928 116014398 116017109 116020876 116022397
SIND : 105157343 105161960 105163347 105168540 105173722 105175978
OEU : 111366090 111369510 111371440 111388038 111394205 111399809 111406368 111408336
EGT : 105950420 105954637 105956283 105970946
SSPL : 121747683 121748810 121752062 121752340 121785070 121787229 121805022 121807651
SMIL : 130988039 131007293 131022806 131026523
SHIS : 125188776 125193215 125213509 125214739
APAN : 127241914 127251466 127255233 127259108 127264149 127264733
HAN : 110868211 110887011 110894590 110909168 110937070 110942429
ECAD : 122582187 122582189 122584953 122585299 122590987 122591036 122602820
LSV : 111885089 111888768 111890876 111895013 111899116 111899117 111916035
CCAV : 112506455 112506605 112511753 112512080 112516432 112520775
DCR : 108196194 108196428 108199296 108202090 108204620 108214576 108216259 108222408
CSIN : 114260358 114260409 114271846 114272476 114289742 114294846
RVL : 131302702 131304639 131314772 131326610
AEW : 130757233 130762153 130767461 130770171 130777867 130790234 130792079
BVG : 104891266 104898912(SBSS1) 104900089 104901675
SOE : 110795334 110800655 110801596 110802994
CQI : 110684034 110689796 110708258 110711114 110715868 110721833 110727927
ATRI : 130814105 130814435 130823694 130827490 130828324
MOF : 131150868 131153294 131154240 131154928 131157276 131159768
NNU : 104590476 104598894 104606206 104606968 104607856
MING : 122065659 122066679 122074938 122078406 122084256 122091871
TSS : 122645961 122656559 122658495 122666254 122667141 122667939
PSOM : 113298313 113303188 113326623 113339936 113345466 113355249
OSA : 4331252 4332788 4333062 4335303 4335447 4340386 4343910
DOSA : Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)
OBR : 102705920 102706647 102712095 102712964 102716200 102717886
OGL : 127763134 127765692 127767368 127771776 127775904 127778463
BDI : 100820943 100821418 100836007 100839938 100840503 100841916
ATS : 109740648 109744619 109746065 109749305 109759549 109766888 109779202
TDC : 119285662 119288144 119296208 119318722 119325817 119327849 119327915 119331447 119335297 119337405 119353790 119356081 119362975 119365225
TAES : 123046325 123048524 123052082 123054180 123083644 123085854 123088341 123092190 123097521 123129210 123140133 123146364 123149843 123150330 123151259 123160342 123164468 123165873 123167316 123187938 123190070 542972 543390
TUA : 125508666 125518000 125521237 125525176 125531634 125536293 125539442 125551720
LPER : 127302408 127314287 127317859 127331575 127332423 127332665 127335947
LRD : 124673966 124681661 124685189 124685213 124698555 124702285 124702413 124702603
SBI : 110431014 110431016 8056263 8077078 8082319
ZMA : 100278478 103634623 103654087 542091 542247 542365
SITA : 101754478 101759310 101762615 101783222 101784175
SVS : 117838151 117840640 117841692 117852648 117852695
PVIR : 120647134 120652113 120652421 120668921 120669798 120690757 120690891 120698689 120702902
PHAI : 112874627 112875082 112879014 112888915 112888930
PDA : 103702434 103702464 103703639 103707262 103711450 103712592 103714824 103717684 120103914
EGU : 105042002 105045149 105053047 105055284 105056682 105057453 105058592 105058897
MUS : 103968600 103976736 103977164 103977647 103978224 103987501 103992334 103995302 103998528
ZOF : 121969154 121975103 121980242 121981702 121984153 121985571 121992446 121996391 122010305 122016627 122019937 122020157 122023544 122023723 122036098 122036396 122037258 122037810 122052153 122053395 122056643
DCT : 110092960 110103989 110110417 110111733
PEQ : 110026604 110026668 110029391 110029413 110035855
AOF : 109819760 109820065 109833647 109845351 109849688
MSIN : 131228225 131230255 131236949 131243083 131251790
NCOL : 116248903 116254170 116255119 116257343 116263220 116264050
SMO : SELMODRAFT_268237(SUS)
PPP : 112272772 112282689 112286164 112287296
APRO : F751_2740 F751_2741
TLR : Thiosp_00203(mfpsA_1)
TFRI : Thiofri_00400(mfpsA_1)
TWG : Thiowin_05095(mfpsA_3)
THIC : TspCOW1_24830(spsA)
CYN : Cyan7425_1752 Cyan7425_3916
LEN : LEP3755_22370 LEP3755_51010
LBO : LBWT_25690 LBWT_4830
GLP : Glo7428_0408 Glo7428_4260
OXY : HCG48_05910 HCG48_11845
MPRO : BJP34_23510 BJP34_29155
MIC : Mic7113_2737 Mic7113_3751
ANA : all1059 all4985(susA)
NPU : Npun_F1876 Npun_F4951
NOS : Nos7107_1514 Nos7107_2802
NOP : Nos7524_2894 Nos7524_5556
NON : NOS3756_14120 NOS3756_17730(susA)
NFL : COO91_03951 COO91_06208
NOE : CLI64_11655 CLI64_26945
NED : HUN01_05920 HUN01_33605
ACY : Anacy_1886 Anacy_4232
ANN : EH233_15730 EH233_28335
CSG : Cylst_0728 Cylst_1832
HBQ : QI031_00830 QI031_18525
CALO : Cal7507_2215 Cal7507_5465
CALN : NIES2098_43090 NIES2098_44440
CALS : NIES3974_05240 NIES3974_21890
RIV : Riv7116_3519 Riv7116_6202
FIS : FIS3754_09190 FIS3754_45090 FIS3754_46950
NSP : BMF81_02875 BMF81_03402
NSPH : BDGGKGIB_01184(susA_1) BDGGKGIB_01317(susA_2)
AEE : IM676_00380 IM676_18815
TOQ : HCG51_14160 HCG51_28585
ALAX : NIES50_21990 NIES50_61790
NCN : BZZ01_03970 BZZ01_08900
PLP : Ple7327_0671 Ple7327_2003
AMUC : Pan181_07010(mfpsA_1)
» show all
Taxonomy
Reference
1
Authors
Avigad, G. and Milner, Y.
Title
UDP-glucose:fructose transglucosylase from sugar beet roots.
Journal
Methods Enzymol 8:341-345 (1966)
Reference
Authors
CARDINI CE, LELOIR LF, CHIRIBOGA J.
Title
The biosynthesis of sucrose.
Journal
J Biol Chem 214:149-55 (1955)
Reference
Authors
Delmer DP.
Title
The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings.
Journal
J Biol Chem 247:3822-8 (1972)
Reference
Authors
Murata T, Sugiyama T, Minamikawa T, Akazawa T.
Title
Enzymic mechanism of starch synthesis in ripening rice grains. 3. Mechanism of the sucrose-starch conversion.
Journal
Reference
Authors
Nakai T, Konishi T, Zhang XQ, Chollet R, Tonouchi N, Tsuchida T, Yoshinaga F, Mori H, Sakai F, Hayashi T.
Title
An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.
Journal
Reference
Authors
Porchia AC, Curatti L, Salerno GL.
Title
Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence.
Journal
Reference
Authors
Ross HA, Davies HV.
Title
Purification and Characterization of Sucrose Synthase from the Cotyledons of Vicia faba L.
Journal
Reference
Authors
Silvius JE, Snyder FW.
Title
Comparative Enzymic Studies of Sucrose Metabolism in the Taproots and Fibrous Roots of Beta vulgaris L.
Journal
Reference
Authors
Tanase K, Yamaki S.
Title
Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit.
Journal
Reference
Authors
Baroja-Fernandez E, Munoz FJ, Saikusa T, Rodriguez-Lopez M, Akazawa T, Pozueta-Romero J
Title
Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.13
ExPASy - ENZYME nomenclature database: 2.4.1.13