KEGG ENZYME: 2.4.1.323

ENZYME: 2.4.1.323

Entry

EC 2.4.1.323                Enzyme

Name

7-deoxyloganetic acid glucosyltransferase;
UGT8

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

UDP-alpha-D-glucose:7-deoxyloganetate O-D-glucosyltransferase

Reaction(IUBMB)

UDP-alpha-D-glucose + 7-deoxyloganetate = UDP + 7-deoxyloganate [RN:R10834]

Reaction(KEGG)

R10834

Substrate

UDP-alpha-D-glucose [CPD:C00029];
7-deoxyloganetate [CPD:C20789]

Product

UDP [CPD:C00015];
7-deoxyloganate [CPD:C11636]

Comment

Isolated from the plant Catharanthus roseus (Madagascar periwinkle). Involved in loganin and secologanin biosynthesis. Does not react with 7-deoxyloganetin. cf. EC 2.4.1.324 7-deoxyloganetin glucosyltransferase.

History

EC 2.4.1.323 created 2014

Pathway

ec00902

Monoterpenoid biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K21373

7-deoxyloganetic acid glucosyltransferase

Reference

1 [PMID:24104568]

Authors

Asada K, Salim V, Masada-Atsumi S, Edmunds E, Nagatoshi M, Terasaka K, Mizukami H, De Luca V

Title

A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle.

Journal

Plant Cell 25:4123-34 (2013)
DOI:10.1105/tpc.113.115154

Sequence

[ag:BAO01109]

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.323

IUBMB Enzyme Nomenclature:

2.4.1.323

ExPASy - ENZYME nomenclature database:

2.4.1.323

BRENDA, the Enzyme Database:

2.4.1.323

DBGET integrated database retrieval system