KEGG ENZYME: 2.4.1.373

ENZYME: 2.4.1.373

Entry

EC 2.4.1.373                Enzyme

Name

alpha-(1->2) branching sucrase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

sucrose:(1->6)-alpha-D-glucan 2-alpha-D-glucosyl-transferase

Reaction(IUBMB)

sucrose + a (1->6)-alpha-D-glucan = D-fructose + a (1->6)-alpha-D-glucan containing a (1->2)-alpha-D-glucose branch [RN:R12528]

Reaction(KEGG)

R12528

Substrate

sucrose [CPD:C00089];
(1->6)-alpha-D-glucan

Product

D-fructose [CPD:C00095];
(1->6)-alpha-D-glucan containing a (1->2)-alpha-D-glucose branch [CPD:C22230]

Comment

The glucansucrases transfer a D-glucosyl residue from sucrose to a glucan chain. They are classified based on the linkage by which they attach the transferred residue. In some cases, in which the enzyme forms more than one linkage type, classification relies on the relative proportion of the linkages that are generated. This enzyme introduces alpha(1->2) branches into (1->6)-alpha-D-glucans.

History

EC 2.4.1.373 created 2019

Orthology

K23981

alpha-(1->2) branching sucrase

Reference

1 [PMID:15601714]

Authors

Fabre E, Bozonnet S, Arcache A, Willemot RM, Vignon M, Monsan P, Remaud-Simeon M

Title

Role of the two catalytic domains of DSR-E dextransucrase and their involvement in the formation of highly alpha-1,2 branched dextran.

Journal

J Bacteriol 187:296-303 (2005)
DOI:10.1128/JB.187.1.296-303.2005

Reference

2 [PMID:23544576]

Authors

Brison Y, Laguerre S, Lefoulon F, Morel S, Monties N, Potocki-Veronese G, Monsan P, Remaud-Simeon M

Title

Branching pattern of gluco-oligosaccharides and 1.5kDa dextran grafted by the alpha-1,2 branching sucrase GBD-CD2.

Journal

Carbohydr Polym 94:567-76 (2013)
DOI:10.1016/j.carbpol.2013.01.064

Reference

3 [PMID:25756290]

Authors

Passerini D, Vuillemin M, Ufarte L, Morel S, Loux V, Fontagne-Faucher C, Monsan P, Remaud-Simeon M, Moulis C

Title

Inventory of the GH70 enzymes encoded by Leuconostoc citreum NRRL B-1299 - identification of three novel alpha-transglucosylases.

Journal

FEBS J 282:2115-30 (2015)
DOI:10.1111/febs.13261

Sequence

[ag:CDX66896]

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.373

IUBMB Enzyme Nomenclature:

2.4.1.373

ExPASy - ENZYME nomenclature database:

2.4.1.373

BRENDA, the Enzyme Database:

2.4.1.373

All links

Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (7)   

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