Entry
Name
CDP-abequose:alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und alpha-1,3-abequosyltransferase;
wbaR (gene name);
rfbR (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
CDP-alpha-D-abequose:2-O-acetyl-alpha-L-rhamnopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 3IV-alpha-abequosyltransferase (configuration retaining)
Reaction(IUBMB)
CDP-alpha-D-abequose + 2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und = CDP + alpha-D-Abe-(1->3)-2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und [RN:
R12744 ]
Reaction(KEGG)
Substrate
CDP-alpha-D-abequose [CPD:
C01788 ];
2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und
Product
CDP [CPD:
C00112 ];
alpha-D-Abe-(1->3)-2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und
Comment
The enzyme, present in Salmonella strains that belong to group C2, participates in the biosynthesis of the repeat unit of O antigens produced by these strains.
History
EC 2.4.1.382 created 2021
Orthology
K25199 O-antigen biosynthesis alpha-1,3-abequosyltransferase
Genes
Taxonomy
Reference
Authors
Liu D, Lindqvist L, Reeves PR
Title
Transferases of O-antigen biosynthesis in Salmonella enterica: dideoxyhexosyltransferases of groups B and C2 and acetyltransferase of group C2.
Journal
Sequence
Reference
Authors
Zhao X, Dai Q, Jia R, Zhu D, Liu M, Wang M, Chen S, Sun K, Yang Q, Wu Y, Cheng A.
Title
Two Novel Salmonella Bivalent Vaccines Confer Dual Protection against Two Salmonella Serovars in Mice.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 2.4.1.382