KEGG   ENZYME: 2.4.1.391
Entry
EC 2.4.1.391                Enzyme                                 
Name
beta-1,2-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
1,2-beta-D-glucan:D-glucoside 2-beta-D-glucosyltransferase (configuration-retaining)
Reaction(IUBMB)
[(1->2)-beta-D-glucosyl]n + a D-glucoside = [(1->2)-beta-D-glucosyl]n-1 + a beta-D-glucosyl-(1->2)-D-glucoside [RN:R13124]
Reaction(KEGG)
R13124
Substrate
[(1->2)-beta-D-glucosyl]n [CPD:C02490];
D-glucoside [CPD:C01798]
Product
[(1->2)-beta-D-glucosyl]n-1;
beta-D-glucosyl-(1->2)-D-glucoside [CPD:C22632]
Comment
The enzyme, characterized from the bacterium Ignavibacterium album, transfers a glucosyl residue from the non-reducing end of a 1,2-beta-D-glucan to a glucose residue of an acceptor molecule, forming a beta(1,2) linkage. The donor molecule can be as small as sophorose (which contains two glucosyl residues). The enzyme has a very broad specificity for the acceptor, and can act on various aryl- and alkyl-glucosides. In addition, the accepting glucose unit can be in either alpha or beta configuration.
History
EC 2.4.1.391 created 2022
Orthology
K26286  beta-1,2-glucosyltransferase
Genes
VCBCYK25_000175
IALIALB_1185
Reference
1  [PMID:35065074]
  Authors
Kobayashi K, Shimizu H, Tanaka N, Kuramochi K, Nakai H, Nakajima M, Taguchi H.
  Title
Characterization and structural analyses of a novel glycosyltransferase acting on the beta-1,2-glucosidic linkages.
  Journal
J Biol Chem 298:101606 (2022)
DOI:10.1016/j.jbc.2022.101606
  Sequence
[ial:IALB_1185]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.391
IUBMB Enzyme Nomenclature: 2.4.1.391
ExPASy - ENZYME nomenclature database: 2.4.1.391
BRENDA, the Enzyme Database: 2.4.1.391

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