Entry
Name
undecaprenyl-phosphate mannosyltransferase;
guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase;
GDP mannose-undecaprenyl phosphate mannosyltransferase;
GDP-D-mannose:lipid phosphate transmannosylase;
GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
GDP-alpha-D-mannose:undecaprenyl-phosphate D-mannosyltransferase
Reaction(IUBMB)
GDP-alpha-D-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol [RN:
R07257 ]
Reaction(KEGG)
Substrate
GDP-alpha-D-mannose [CPD:
C00096 ];
undecaprenyl phosphate [CPD:
C17556 ]
Product
GDP [CPD:
C00035 ];
D-mannosyl-1-phosphoundecaprenol [CPD:
C15542 ]
Comment
Requires phosphatidylglycerol.
History
EC 2.4.1.54 created 1972
Reference
Authors
Lahav M, Chiu TH, Lennarz WJ.
Title
Studies on the biosynthesis of mannan in Micrococcus lysodeikticus. II. The enzymatic synthesis of mannosyl-l-phosphoryl-undecaprenol.
Journal
J Biol Chem 244:5890-8 (1969)
Reference
Authors
Rush JS, Waechter CJ
Title
Partial purification of mannosylphosphorylundecaprenol synthase from Micrococcus luteus: a useful enzyme for the biosynthesis of a variety of mannosylphosphorylpolyisoprenol products.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.54
ExPASy - ENZYME nomenclature database: 2.4.1.54