KEGG ENZYME: 2.5.1.121

ENZYME: 2.5.1.121

Entry

EC 2.5.1.121                Enzyme

Name

5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase;
PpzP;
dihydrophenazine-1-carboxylate dimethylallyltransferase;
5,10-dihydrophenazine 1-carboxylate dimethylallyltransferase;
dimethylallyl diphosphate:5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase

Class

Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

Sysname

prenyl-diphosphate:5,10-dihydrophenazine-1-carboxylate 9-prenyltransferase

Reaction(IUBMB)

prenyl diphosphate + 5,10-dihydrophenazine-1-carboxylate = diphosphate + 9-prenyl-5,10-dihydrophenazine-1-carboxylate [RN:R10966]

Reaction(KEGG)

R10966

Substrate

prenyl diphosphate [CPD:C00235];
5,10-dihydrophenazine-1-carboxylate [CPD:C20981]

Product

diphosphate [CPD:C00013];
9-prenyl-5,10-dihydrophenazine-1-carboxylate [CPD:C20982]

Comment

The enzyme is involved in the biosynthesis of prenylated phenazines by the bacterium Streptomyces anulatus. It is specific for both prenyl diphosphate and 5,10-dihydrophenazine-1-carboxylate.

History

EC 2.5.1.121 created 2014

Pathway

ec00405

Phenazine biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K21338

5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase

Reference

1 [PMID:19339241]