KEGG   ENZYME: 2.5.1.122
Entry
EC 2.5.1.122                Enzyme                                 
Name
4-O-dimethylallyl-L-tyrosine synthase;
SirD;
dimethylallyl diphosphate:L-tyrosine 4-O-dimethylallyltransferase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
prenyl-diphosphate:L-tyrosine 4-O-prenyltransferase
Reaction(IUBMB)
prenyl diphosphate + L-tyrosine = diphosphate + 4-O-prenyl-L-tyrosine [RN:R10968]
Reaction(KEGG)
R10968
Substrate
prenyl diphosphate [CPD:C00235];
L-tyrosine [CPD:C00082]
Product
diphosphate [CPD:C00013];
4-O-prenyl-L-tyrosine [CPD:C20983]
Comment
The enzyme is involved in biosynthesis of the phytotoxin sirodesmin PL by the phytopathogenic ascomycete Leptosphaeria maculans.
History
EC 2.5.1.122 created 2014
Orthology
K21339  4-O-dimethylallyl-L-tyrosine synthase
Genes
PPEI: PpBr36_10871
PGRI: PgNI_08061
CHIG: CH63R_03950 CH63R_07283 CH63R_14373
TMF: EYB26_001585
BZE: COCCADRAFT_96963
BSC: COCSADRAFT_41511
BOR: COCMIDRAFT_31681
ARAB: EKO05_0003262
MORE: E1B28_013476
Reference
1  [PMID:19762440]
  Authors
Kremer A, Li SM
  Title
A tyrosine O-prenyltransferase catalyses the first pathway-specific step in the biosynthesis of sirodesmin PL.
  Journal
Microbiology 156:278-86 (2010)
DOI:10.1099/mic.0.033886-0
  Sequence
[ag:AAS92554]
Reference
2  [PMID:21038099]
  Authors
Zou HX, Xie X, Zheng XD, Li SM
  Title
The tyrosine O-prenyltransferase SirD catalyzes O-, N-, and C-prenylations.
  Journal
Appl Microbiol Biotechnol 89:1443-51 (2011)
DOI:10.1007/s00253-010-2956-x
  Sequence
[ag:AAS92554]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.122
IUBMB Enzyme Nomenclature: 2.5.1.122
ExPASy - ENZYME nomenclature database: 2.5.1.122
BRENDA, the Enzyme Database: 2.5.1.122

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (12)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (2)   
Protein domain (3)   
   InterPro (3)   
All databases (26)   

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