hapalindole G dimethylallyltransferase;
ambP3 (gene name);
famD1 (gene name)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
prenyl-diphosphate:hapalindole G prenyltransferase (ambiguine A-forming)
Reaction(IUBMB)
(1) prenyl diphosphate + hapalindole G = ambiguine A + diphosphate [RN:R13303];
(2) prenyl diphosphate + hapalindole U = ambiguine H + diphosphate [RN:R13304]
prenyl diphosphate [CPD:C00235];
hapalindole G [CPD:C21974];
hapalindole U [CPD:C21973]
Product
ambiguine A [CPD:C22903];
diphosphate [CPD:C00013];
ambiguine H [CPD:C22905]
Comment
Requires Mg2+. The enzyme, characterized from the cyanobacterium Fischerella ambigua UTEX 1903, is involved in the biosynthesis of hapalindole-type alkaloids.
