KEGG ENZYME: 2.5.1.79

ENZYME: 2.5.1.79

Entry

EC 2.5.1.79                 Enzyme

Name

thermospermine synthase;
TSPMS;
ACL5;
SAC51;
S-adenosyl 3-(methylthio)propylamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing)

Class

Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

Sysname

S-adenosyl 3-(methylsulfanyl)propylamine:spermidine 3-aminopropyltransferase (thermospermine-forming)

Reaction(IUBMB)

S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+ [RN:R09531]

Reaction(KEGG)

R09531

Substrate

S-adenosyl 3-(methylsulfanyl)propylamine [CPD:C01137];
spermidine [CPD:C00315]

Product

S-methyl-5'-thioadenosine [CPD:C00170];
thermospermine [CPD:C19669];
H+ [CPD:C00080]

Comment

This plant enzyme is crucial for the proper functioning of xylem vessel elements in the vascular tissues of plants [3].

History

EC 2.5.1.79 created 2010, modified 2013

Orthology

K18787

thermospermine synthase

Genes

ATH:	AT5G19530(ACL5)

ALY:

9307961

CRB:	17882428 17889563

CSAT:

104703138 104706283 104714077 104736021 104770319

EUS:	EUTSA_v10002037mg EUTSA_v10013833mg

BRP:	103845743 103851278

BNA:	106367869 106371801 106380754 106425813

BOE:	106315154 106321129 106322697

RSZ:

108842156

THJ:

104811216

CPAP:

110809258 110814092

CIT:	102612657 102622802

CIC:	CICLE_v10005374mg CICLE_v10008847mg

PVY:	116117534 116130523 116146874

MINC:

123194421 123194453 123201000 123220390

TCC:	18588133 18602963

GRA:

105773375

GHI:	107901009 107961656

GAB:

108472457

HSYR:

120141386 120147835 120182241 120183596 120192436 120201027

DZI:	111285735 111291353 111300407

EGR:	104414850 104437922

GMX:	100781850 100784972 100801533 100815510 100819011

GSJ:	114370275 114383148 114386651 114392509 114401671

PVU:	PHAVU_001G039100g PHAVU_007G056100g

VRA:	106763861 106780391

VAR:	108325202 108337212

VUN:	114190212 114193245

VUM:	124834553 124846692

CCAJ:

109788091 109815944 109815946 109817933

APRC:

113847763 113852329 113864755 113869732 113873236

MTR:	11426725 11435403 11439099

TPRA:

123894210 123907878 123916515

CAM:	101494168 101497824 101498474 101508614

PSAT:

127076815 127092452 127119655

VVO:	131596378 131652608

LJA:	Lj5g3v0465980.1(Lj5g3v0465980.1) Lj5g3v2046170.1(Lj5g3v2046170.1)

ADU:	107466955 107466956 107495634

AIP:	107605476 107617166 107617167 107639673

AHF:	112697639 112711802 112711807 112743722 112755880 112780084 112780085

LANG:

109326777 109327765 109336169 109351122 109358185

PCIN:

129302368 129318706 129320799

QSA:	O6P43_002683 O6P43_003380 O6P43_015848 O6P43_022469

FVE:	101301387 101303245 101309294 101314831

RCN:	112174344 112199765

PPER:

18769504 18789648 18793824

PMUM:

103320626 103324273 103340560

PAVI:

110762047 110764722

PDUL:

117614044 117614700 117634283

MDM:	103420776 103438320 103440896 103455791

MSYL:

126596573 126601318 126606683 126631891

PXB:	103927488 103935976 103952624 103956625

ZJU:	107420166 107423202 125423913

MNT:	21395590 21401549 21409976

CSAV:

115706322 115721778

CSV:	101210030 101214242 101221818

CMO:	103483717 103488520 103498720

BHJ:	120071854 120076858 120080033

MCHA:

111004633 111009509 111021857

CMAX:

111472239 111474176 111492169 111493662

CMOS:

111441602 111450716 111462336

CPEP:

111800003 111805444 111805620

RCU:	8258569 8261463

JCU:	105631971 105638095

HBR:	110632830 110645455 110673168

MESC:

110601323 110603650 110611001

POP:	7473401 7491997 7498087

PEU:	105119549 105122138 105123584 105126958

PALZ:

118030740 118046623 118055852

JRE:	108985234 108999082 109005851

CILL:

122275203 122295653 122300550

CAVE:

132184786 132185729

QSU:	112008627 112037415 112038640

QLO:	115974856 115993764

TWL:	120006388 120013613 120014685

VVI:	100242399 100258046

VRI:	117912175 117913986

SLY:	101247938 101255533 543797(spe4)

SPEN:

107025671 107026968 107029432

SOT:	102579767 102585779 102595598

SSTN:

125841505 125860591 125871427 125876198

SDUL:

129881810 129889191 129899817

CANN:

107857586 107864110

LBB:	132605094 132610921 132635968

NTA:	107776201 107790611 107794930 107795697 107823555 107825327

NSY:	104232751 104233312 104249204

NTO:	104088830 104106389 104109182

NAU:	109212934 109222489 109232156 109234060

INI:	109163474 109163802 109190822

ITR:	116006078 116032083

SIND:

105164631 105171338

OEU:	111373552 111379571 111397580

EGT:	105953330 105977251

SSPL:

121750594 121783792 121785555 121794059

SMIL:

130991499 130995209 131015413

SHIS:

125212034 125219537

APAN:

127248645 127265557

HAN:	110885234 110885237 110918878

ECAD:

122590694 122595623

LSV:	111881784 111890805

CCAV:

112506010 112516992

DCR:	108197654 108198722 108206157

CSIN:

114265396 114287062

RVL:

131321656

AEW:	130756300 130764228 130771263 130793559

BVG:	104884037 104886577

SOE:

110795108

CQI:	110684982 110705387 110710176

ATRI:

130804288 130825293

MOF:	131150832 131152214

NNU:	104600597 104611903

MING:

122071251 122077321 122091104

TSS:	122642297 122666841 122670047

PSOM:

113333302 113347571 113350318 113353026

OSA:

4328835

DOSA:

Os02t0237100-01(Os02g0237100)

OBR:

102706354

OGL:

127761668

BDI:

100829809

ATS:

109775813

TDC:

119287738

TAES:

123088045 123167568

LPER:

127327702 127342104

SBI:

8062753

SITA:

101757460 101768731

SVS:	117841448 117842598

PVIR:

120660809 120680330

PHAI:

112879597

PDA:	103704892 103716455 120111749

EGU:	105041819 105046505 105053105 105055022

MUS:	103977616 103990371

ZOF:	121973738 121977869 122001343 122003667 122003668

DCT:	110096444 110110528

PEQ:	110021024 110029175

AOF:	109833763 109845476

MSIN:

131251690

NCOL:

116256347 116261719

ATR:	18428883 18439402

SMO:	SELMODRAFT_182311 SELMODRAFT_184074 SELMODRAFT_234232 SELMODRAFT_74817

PPP:	112278342 112282054 112283116

CRE:	CHLRE_06g251500v5

VCN:	VOLCADRAFT_76291

MNG:

MNEG_7203

CSL:	COCSUDRAFT_26844

OLU:	OSTLU_40897(SPD2)

OTA:	OT_ostta06g00580

BPG:	Bathy05g00430

MIS:	MICPUN_80273

MPP:	MICPUCDRAFT_49612(JGI:MicpuC2_49612)

FCY:	FRACYDRAFT_206948(Fc_206948)

TPS:	THAPSDRAFT_269901

AAF:	AURANDRAFT_31657(SPS1)

PIF:	PITG_17608

PSOJ:

PHYSODRAFT_518702

EHX:	EMIHUDRAFT_430738

GTT:	GUITHDRAFT_66141

» show all

Reference

1 [PMID:19075322]

Authors

Romer P, Faltermeier A, Mertins V, Gedrange T, Mai R, Proff P

Title

Investigations about N-aminopropyl transferases probably involved in biomineralization.

Journal

J Physiol Pharmacol 59 Suppl 5:27-37 (2008)

Reference

2 [PMID:17560575]

Authors

Knott JM, Romer P, Sumper M

Title

Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine.

Journal

FEBS Lett 581:3081-6 (2007)
DOI:10.1016/j.febslet.2007.05.074

Sequence

[ath:AT5G19530]

Reference

3 [PMID:18599510]

Authors

Muniz L, Minguet EG, Singh SK, Pesquet E, Vera-Sirera F, Moreau-Courtois CL, Carbonell J, Blazquez MA, Tuominen H

Title

ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death.

Journal

Development 135:2573-82 (2008)
DOI:10.1242/dev.019349

Sequence

[ath:AT5G19530]

Other DBs

ExplorEnz - The Enzyme Database:

2.5.1.79

IUBMB Enzyme Nomenclature:

2.5.1.79

ExPASy - ENZYME nomenclature database:

2.5.1.79

BRENDA, the Enzyme Database:

2.5.1.79

DBGET integrated database retrieval system