KEGG ENZYME: 2.6.1.104

ENZYME: 2.6.1.104

Entry

EC 2.6.1.104                Enzyme

Name

3-dehydro-glucose-6-phosphate---glutamate transaminase;
3-oxo-glucose-6-phosphate:glutamate aminotransferase;
ntdA (gene name)

Class

Transferases;
Transferring nitrogenous groups;
Transaminases

Sysname

kanosamine 6-phosphate:2-oxoglutarate aminotransferase

Reaction(IUBMB)

kanosamine 6-phosphate + 2-oxoglutarate = 3-dehydro-D-glucose 6-phosphate + L-glutamate [RN:R10698]

Reaction(KEGG)

R10698

Substrate

kanosamine 6-phosphate [CPD:C12213];
2-oxoglutarate [CPD:C00026]

Product

3-dehydro-D-glucose 6-phosphate [CPD:C20668];
L-glutamate [CPD:C00025]

Comment

A pyridoxal-phosphate protein. The enzyme, found in the bacterium Bacillus subtilis, is involved in a kanosamine biosynthesis pathway.

History

EC 2.6.1.104 created 2014

Pathway

ec00998

Biosynthesis of various antibiotics

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K18653

3-dehydro-glucose-6-phosphate---glutamate transaminase

Genes

ECV:	APECO1_O1CoBM86

YEL:	LC20_02629

PROD:

PCO85_21240

EAM:	EAMY_0627(yhjL)

EAY:	EAM_2803(ntdA)

EPY:

EpC_29560

EPR:	EPYR_03197(yhjL)

ERJ:	EJP617_17800

XBV:	XBW1_3412(ntdA)

RHEY:

FEE42_04990

BSU:	BSU10550(ntdA)

BSR:

I33_1189

BSL:

A7A1_3679

BSH:	BSU6051_10550(ntdA)

BSY:	I653_05335

BSUT:

BSUB_01152(ntdA)

BSUL:

BSUA_01152(ntdA)

BSUS:

Q433_05970

BSO:	BSNT_07499(yhjL)

BSN:	BSn5_17160

BSQ:	B657_10550(ntdA)

BSX:	C663_1079(ntdA)

BSP:	U712_05390

BSS:	BSUW23_05350(ntdA)

BST:

GYO_1359

BIT:	BIS30_15985

BLI:	BL03980(ntdA)

BLD:	BLi03946(ntdA)

BLH:	BaLi_c39610(ntdA)

BSON:

S101395_00443(ntdA)

BHT:	DIC78_04330

BMOJ:

HC660_11110(ntdA)

BTEQ:

G4P54_05595

BAT:

BAS3048

BAH:	BAMEG_1338 BAMEG_1339

BAX:	H9401_3125 H9401_3126

BANS:

BAPAT_3142 BAPAT_3143

BANV:

DJ46_2023 DJ46_2024

BCU:	BCAH820_3273

BCX:

BCA_3326

BCF:

bcf_16050

BTL:

BALH_2925

BTHT:

H175_233p030

BTW:

BF38_4422

BWD:	CT694_13230

BMOB:

MLA2C4_13365

BALU:

QRY64_18575

BPU:

BPUM_0280

BPUM:

BW16_01755

BPUS:

UP12_01730

BXI:	BK049_06530

BALT:

CFN77_01755

BAER:

BAE_09295

BSAF:

BSL056_01695

BCAB:

EFK13_05955

BACW:

QR42_01710

BACY:

QF06_04210

BACL:

BS34A_11690(ntdA)

BALM:

BsLM_1098

BZH:	NF868_01570

BAEI:

RE735_17415

BGI:	BGM20_20550

SMUS:

C7J88_03315

SCHR:

DWB92_11000

SFF:	FOB90_09095

PCHI:

PC41400_15410

MAB:

MAB_2610

MMV:	MYCMA_1411

MABB:

MASS_2568

MABL:

MMASJCM_2587

MIZ:	BAB75_14135

MSAO:

MYCSP_09820

SMA:	SAVERM_834

SHAW:

CEB94_31530

SVD:	CP969_03730

SKG:	KJK29_07475

MSIL:

METEAL_26040(ntdA)

» show all

Reference

1 [PMID:19342798]

Authors

van Straaten KE, Langill DM, Palmer DR, Sanders DA

Title

Purification, crystallization and preliminary X-ray analysis of NtdA, a putative pyridoxal phosphate-dependent aminotransferase from Bacillus subtilis.

Journal

Acta Crystallogr Sect F Struct Biol Cryst Commun 65:426-9 (2009)
DOI:10.1107/S1744309109009038

Reference

2 [PMID:23586652]

Authors

Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR

Title

A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.

Journal

J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255

Sequence

[bsu:BSU10550]

Other DBs

ExplorEnz - The Enzyme Database:

2.6.1.104

IUBMB Enzyme Nomenclature:

2.6.1.104

ExPASy - ENZYME nomenclature database:

2.6.1.104

BRENDA, the Enzyme Database:

2.6.1.104

DBGET integrated database retrieval system