KEGG ENZYME: 2.6.1.109

ENZYME: 2.6.1.109

Entry

EC 2.6.1.109                Enzyme

Name

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase;
kdnA (gene name)

Class

Transferases;
Transferring nitrogenous groups;
Transaminases

Sysname

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate:2-oxoglutarate aminotransferase

Reaction(IUBMB)

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate = 8-dehydro-3-deoxy-alpha-D-manno-octulosonate + L-glutamate

Reaction(KEGG)

(other) R11395

Substrate

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate;
2-oxoglutarate [CPD:C00026]

Product

8-dehydro-3-deoxy-alpha-D-manno-octulosonate;
L-glutamate [CPD:C00025]

Comment

The enzyme, characterized from the bacterium Shewanella oneidensis, forms 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC 1.1.3.48, 3-deoxy-alpha-D-manno-octulosonate 8-oxidase.

History

EC 2.6.1.109 created 2015

Orthology

K19715

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase

Genes

XGR:	QL128_12425

SON:

SO_2476

SDN:

Sden_2132

SFR:

Sfri_1761

SAZ:

Sama_1641

SBL:

Sbal_2373

SBM:	Shew185_2361

SBN:	Sbal195_2476

SBP:	Sbal223_1986

SBT:	Sbal678_2478

SBS:	Sbal117_2505

SBB:	Sbal175_2010

SLO:

Shew_1858

SSE:

Ssed_2422

SHE:	Shewmr4_1853

SHM:	Shewmr7_2125

SHN:	Shewana3_1908

SHL:

Shal_2314

SWD:

Swoo_2184

SWP:

swp_2702

SVO:

SVI_1929

SHF:	CEQ32_05205

SJA:	SJ2017_2241

SPSW:

Sps_00649

SBJ:	CF168_11170

SMAV:

CFF01_10070

SHEW:

CKQ84_20690

SALG:

BS332_18890

SLJ:	EGC82_12950

SMAI:

EXU30_01055

SPOL:

FH971_08665

SBK:	SHEWBE_2916(kdnA)

SKH:	STH12_01316(arnB)

SLIT:

JQC75_08195

SDK:	KHX94_17815

SCAA:

TUM17387_18780(kdnA)

SPSH:

FM037_12455

SEUR:

FM038_013205

SYK:	KDN34_08385

SCYP:

JYB88_09490

SSEM:

JYB85_09705

SGLA:

FJ709_08350

SXM:	MKD32_09550

SVM:	KDH10_000740

SSEH:

N7V09_13795

SCHK:

GII14_12410

SAEG:

K0H80_09445

SDEO:

D0436_09810

SMES:

K0I73_09990

SHAO:

K0H81_10465

SZH:	K0H63_08855

SSPA:

K0I31_09595

SHNS:

K0J45_09480

SRHS:

K0I63_09605

SMAY:

K0H60_09690

SOG:	RA178_10650(kdnA)

SPSR:

EGC80_17955

TCX:

Tcr_2139

HTR:	EPV75_11755

HMAR:

HVMH_2251(kdnA)

TCY:	Thicy_0075

TAO:	THIAE_00480

THIO:

AYJ59_01145

THIG:

FE785_10505

TIB:	THMIRHAM_22010(kdnA)

TLH:	NR989_11345

TZO:	THMIRHAT_01680(kdnA)

SHD:	SUTH_03378

DPS:

DP1941

DSF:

UWK_02931

DLM:	DPPLL_15300(kdnA)

DAK:	DaAHT2_0945

DPR:	Despr_1064

DEO:	CAY53_03855

DOG:	HP555_13540

DBK:	DGMP_15160(kdnA)

DDU:	GF1_15250(kdnA)

ECOM:

QTN59_06060

DOL:

Dole_3203

DAL:

Dalk_0883

DTO:	TOL2_C12570

DOV:	DSCO28_27070(kdnA)

DWD:	DSCW_63360(kdnA)

DALK:

DSCA_59390(kdnA)

DML:	Dmul_14440

DLI:

dnl_32050

DMM:	dnm_065170

SAT:

SYN_02056

DTI:	Desti_2928

DBR:

Deba_0659

DMP:	FAK_13860(kdnA)

SRIM:

CP984_18240

SSUB:

CP968_05800

TAI:

Taci_1278

CPOR:

BED41_03565

TLI:

Tlie_0563

AMO:	Anamo_0328

ARAM:

KAR29_09610

CPI:

Cpin_0802

CHIT:

FW415_04000

CHIH:

GWR21_19585

COY:	HF329_25085

CFIL:

MYF79_04000

CHF:	KTO58_23645

CHOR:

MKQ68_22125

CSAC:

SIO70_05315

NKO:	Niako_6241

FGG:	FSB75_15275

ARB:	A9P82_08645

ARK:	D6B99_01875

FLN:

FLA_5379

PSEG:

D3H65_23505

PGIN:

FRZ67_09625

PGO:	FSB84_06350

FLS:	GLV81_01600

FLP:	LK994_04075

FLV:	KJS94_15445

SEDT:

TEGAF0_16090(kdnA)

SCN:	Solca_3571

SLI:

Slin_2804

SRD:	SD10_14800

SMON:

AWR27_24360

SPIR:

CWM47_00650

SPIK:

EXU85_18840

SPIB:

G8759_31780

SRHO:

HH216_12960

SOQ:	LQ777_05965

SFOL:

H3H32_15165

SENF:

GJR95_33315

RSI:	Runsl_3570

RUN:	DR864_07925

RUP:	DTQ70_05240

FLM:

MY04_1600

FLL:	EI427_09795

FYA:	KMW28_08205

FKA:	KM029_00745

CHRW:

KA713_00130

CHK:	D4L85_02655

RSR:	T7867_17635

RBI:	RB2501_14269

CAT:	CA2559_06270

FBC:	FB2170_12561

MARM:

YQ22_15670

MART:

BTR34_15530

MARB:

CJ263_00045

MARE:

EJ994_06035

CAO:	Celal_3619

CLY:	Celly_3038

CLH:	IX49_15320

CBAL:

M667_14775

CBAT:

M666_14725

COMN:

PBN93_15220

LAN:	Lacal_2197

LVN:	BWR22_09230

LACI:

CW733_03215

LNU:	N7U66_03205

ZGA:	ZOBELLIA_4625

ZLA:	Q5W13_22290

ASL:	Aeqsu_3069

AEV:	EI546_01345

AIC:	JK629_14135

PHG:	KCTC32516_02299(kdnA)

WIN:

WPG_2736

WIJ:	BWZ20_14770

SZE:	AW14_13120

AHZ:	APS56_02460

SYI:	SB49_03280

FOR:	FORMB_25820

FOH:	FORMA_18200

FOP:	FNB79_00400

SEON:

BWZ22_15280

AALG:

AREALGSMS7_04131(kdnA)

OLL:	CW732_11005

OAQ:	DZC78_00510

FEK:	C1H87_01875

TAJ:	C1A40_17795

AUE:	C5O00_11085

KOS:	KORDIASMS9_03070(kdnA)

KAN:	IMCC3317_45580(kdnA)

MARF:

CJ739_3663

AQB:	D1818_24600

AQA:	D1815_07685

AQD:	D1816_06985

EMAR:

D1013_12980

MUR:	EQY75_05530

PSYN:

E9099_18385

PPON:

MUN68_005335

OCI:	FEZ18_00090

MGEL:

G5B37_04745

MESQ:

C7H62_2665

GAA:	HX109_13255

CAGG:

HYG79_16075

ALTI:

ALE3EI_2524

MARX:

INR76_09975

SINH:

LS482_15815

ASAG:

FGM00_08320

FLG:	LV716_15575

FLB:	LV704_16960

MRS:	Murru_3316

MLT:

VC82_2956

MUT:	GVT53_08315

MAQI:

LDL77_19005

SPON:

HME9304_03325(wbpE)

SABU:

MBM09_08390

BIA:	GMA17_05680

FBM:	MQE35_00340

ALUT:

O5O44_10700

LUY:	QZH61_09110

AEST:

RBH94_12765

MANG:

RBH95_07535

HWS:	RNZ46_14420

FBU:	UJ101_00786

APIB:

G8C43_02775

» show all

Reference

1 [PMID:23413030]

Authors

Gattis SG, Chung HS, Trent MS, Raetz CR

Title

The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis.

Journal

J Biol Chem 288:9216-25 (2013)
DOI:10.1074/jbc.M113.453324

Sequence

[son:SO_2476]

Other DBs

ExplorEnz - The Enzyme Database:

2.6.1.109

IUBMB Enzyme Nomenclature:

2.6.1.109

ExPASy - ENZYME nomenclature database:

2.6.1.109

BRENDA, the Enzyme Database:

2.6.1.109

DBGET integrated database retrieval system