Entry
Name
vanillin aminotransferase;
VAMT (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-alanine:vanillin aminotransferase
Reaction(IUBMB)
L-alanine + vanillin = pyruvate + vanillylamine [RN:
R12622 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme participates in the biosynthesis of capsaicinoids in pungent cultivars of Capsicum sp. In vivo it has only been assayed in the reverse direction, where the preferred amino group acceptors were found to be pyruvate and oxaloacetate.
History
EC 2.6.1.119 created 2020
Pathway
ec00996 Biosynthesis of various alkaloids
ec01110 Biosynthesis of secondary metabolites
Orthology
K24276 vanillin aminotransferase
Genes
Taxonomy
Reference
1
Authors
Curry, J., Aluru, M., Mendoza, M., Nevarez, J., Melendrez, M. and O'Connell, M.A.
Title
Transcripts for possible capsaicinoid biosynthetic genes are differentially accumulated in pungent and non-pungent Capsicum spp.
Journal
Plant Sci 148:47-57 (1999)
Reference
Authors
del Rosario Abraham-Juarez M, del Carmen Rocha-Granados M, Lopez MG, Rivera-Bustamante RF, Ochoa-Alejo N
Title
Virus-induced silencing of Comt, pAmt and Kas genes results in a reduction of capsaicinoid accumulation in chili pepper fruits.
Journal
Reference
Authors
Lang Y, Kisaka H, Sugiyama R, Nomura K, Morita A, Watanabe T, Tanaka Y, Yazawa S, Miwa T.
Title
Functional loss of pAMT results in biosynthesis of capsinoids, capsaicinoid analogs, in Capsicum annuum cv. CH-19 Sweet.
Journal
Reference
Authors
Gururaj HB, Padma MN, Giridhar P, Ravishankar GA
Title
Functional validation of Capsicum frutescens aminotransferase gene involved in vanillylamine biosynthesis using Agrobacterium mediated genetic transformation studies in Nicotiana tabacum and Capsicum frutescens calli cultures.
Journal
Sequence
Reference
Authors
Weber N, Ismail A, Gorwa-Grauslund M, Carlquist M
Title
Biocatalytic potential of vanillin aminotransferase from Capsicum chinense.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.6.1.119