Entry
Name
[amino-group carrier protein]-gamma-(L-ornithyl)-L-glutamate aminotransferase;
lysJ (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
2-oxoglutarate:[amino-group carrier protein]-C-terminal-[gamma-(L-ornithyl)-L-glutamate] aminotransferase
Reaction(IUBMB)
an [amino-group carrier protein]-C-terminal-[gamma-(L-ornithyl)-L-glutamate] + 2-oxoglutarate = an [amino-group carrier protein]-C-terminal-[gamma-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate] + L-glutamate
Substrate
[amino-group carrier protein]-C-terminal-[gamma-(L-ornithyl)-L-glutamate];
2-oxoglutarate [CPD:
C00026 ]
Product
[amino-group carrier protein]-C-terminal-[gamma-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate];
L-glutamate [CPD:
C00025 ]
Comment
The enzyme participates in an L-arginine biosynthetic pathway that operates in certain species of archaea. In some cases the enzyme also catalyses the activity of EC
2.6.1.118 , [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase.
History
EC 2.6.1.124 created 2022
Pathway
Orthology
K05830 [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
Genes
DTAE : LAJ19_05695 LAJ19_17015
CABY : Cabys_1935 Cabys_3152(argD)
HPEL : HZS54_04340 HZS54_10875
STO : STK_01910(argD_lysJ)
» show all
Taxonomy
Reference
Authors
Yoshida A, Tomita T, Atomi H, Kuzuyama T, Nishiyama M
Title
Lysine Biosynthesis of Thermococcus kodakarensis with the Capacity to Function as an Ornithine Biosynthetic System.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.6.1.124