| Entry |
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| Name |
tryptophan---phenylpyruvate transaminase;
L-tryptophan-alpha-ketoisocaproate aminotransferase
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| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
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| Sysname |
L-tryptophan:phenylpyruvate aminotransferase
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| Reaction(IUBMB) |
L-tryptophan + phenylpyruvate = (indol-3-yl)pyruvate + L-phenylalanine [RN: R01376]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
(indol-3-yl)pyruvate [CPD: C00331];
L-phenylalanine [CPD: C00079]
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| Comment |
Valine, leucine and isoleucine can replace tryptophan as amino donor.
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| History |
EC 2.6.1.28 created 1972
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| Orthology |
| K05821 | aromatic amino acid aminotransferase II |
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| Genes |
| NCS: | NCAS_0B07220(NCAS0B07220) |
| NDI: | NDAI_0B04550(NDAI0B04550) |
| TPF: | TPHA_0O01520(TPHA0O01520) |
| TBL: | TBLA_0B00990(TBLA0B00990) |
| TDL: | TDEL_0F00900(TDEL0F00900) |
| KNG: | KNAG_0H03730(KNAG0H03730) |
| PPA: | PAS_chr1-3_0154 PAS_chr4_0147 |
| CAL: | CAALFM_C405560CA(ARO9) |
| PKZ: | C5L36_0E05810 C5L36_0E05820 |
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| Reference |
1 |
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| Authors |
Koide, Y., Honma, M. and Shimomura, T. |
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| Title |
L-Tryptophan-alpha-ketoisocaproate aminotransferase from Pseudomonas sp. |
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| Journal |
Agric Biol Chem 44:2013-2019 (1980) |
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| Reference |
|
|---|
| Authors |
Sukanya NK, Vaidyanathan CS. |
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| Title |
Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.6.1.28 |
| ExPASy - ENZYME nomenclature database: | 2.6.1.28 |
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