KEGG   ENZYME: 2.7.1.118
Entry
EC 2.7.1.118                Enzyme                                 
Name
ADP---thymidine kinase;
ADP:dThd phosphotransferase;
adenosine diphosphate-thymidine phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ADP:thymidine 5'-phosphotransferase
Reaction(IUBMB)
ADP + thymidine = AMP + dTMP [RN:R01568]
Reaction(KEGG)
R01568
Substrate
ADP [CPD:C00008];
thymidine [CPD:C00214]
Product
AMP [CPD:C00020];
dTMP [CPD:C00364]
Comment
The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC 2.7.1.21 (thymidine kinase), EC 2.7.1.114 (AMP---thymidine kinase) and EC 2.7.4.9 (dTMP kinase).
History
EC 2.7.1.118 created 1986
Reference
1  [PMID:6293576]
  Authors
Falke D, Labenz J, Brauer D, Muller WE.
  Title
Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase.
  Journal
Biochim Biophys Acta 708:99-103 (1982)
DOI:10.1016/0167-4838(82)90207-2
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.118
IUBMB Enzyme Nomenclature: 2.7.1.118
ExPASy - ENZYME nomenclature database: 2.7.1.118
BRENDA, the Enzyme Database: 2.7.1.118
CAS: 82114-39-4

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
All databases (7)   

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