KEGG ENZYME: 2.7.1.179

ENZYME: 2.7.1.179

Entry

EC 2.7.1.179                Enzyme

Name

kanosamine kinase;
rifN (gene name)

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ATP:kanosamine 6-phosphotransferase

Reaction(IUBMB)

ATP + kanosamine = ADP + kanosamine 6-phosphate [RN:R06588]

Reaction(KEGG)

R06588

Substrate

ATP [CPD:C00002];
kanosamine [CPD:C12212]

Product

ADP [CPD:C00008];
kanosamine 6-phosphate [CPD:C12213]

Comment

The enzyme from the bacterium Amycolatopsis mediterranei is specific for kanosamine.

History

EC 2.7.1.179 created 2013

Pathway

ec01051

Biosynthesis of ansamycins

ec01110

Biosynthesis of secondary metabolites

Orthology

K16018

kanosamine 6-kinase

Genes

SVL:	Strvi_5366

SMAL:

SMALA_0448 SMALA_1353

SSOI:

I1A49_05760 I1A49_10265

SRW:	TUE45_00083(rifN) TUE45_pSRc_0216(rifN)

SLE:	cxmN(cxmN)

SPAV:

Spa2297_32600

SAUO:

BV401_06000 BV401_10580

SVU:	B1H20_29915

SPUN:

BFF78_27090

SPHV:

F9278_17910

SSPB:

CP982_35340

SCYG:

S1361_01065(rifN1) S1361_34030(rifN2)

SCAL:

I6J39_29720

SDD:	D9753_04160

STAA:

LDH80_10630

SANT:

QR300_38710

YIA:	LO772_07405

NAKE:

KGD83_16415

FRA:	Francci3_0432

FRE:	Franean1_1662

FAL:

FRAAL0917

SEN:	SACE_2869(rifN)

AMD:	AMED_0630(rifN)

AMN:

RAM_03220

AMM:	AMES_0628(rifN)

AMZ:	B737_0629(rifN)

AAB:	A4R43_38520

AMYY:

YIM_39455(rifN)

AORI:

SD37_11005

PSEE:

FRP1_29595

PECQ:

AD017_32800

APRE:

CNX65_16255

AMI:

Amir_3285

ACTA:

C1701_25890

SAQ:

Sare_1275

MAU:	Micau_2445

MIL:

ML5_5917

MICB:

MicB006_3071

MCAB:

HXZ27_10290

MSAG:

GCM10017556_49820(rifN)

MCHL:

PVK74_10440

MFEU:

H1D33_20275

ACTN:

L083_2901 L083_5701

PLAB:

C6361_34550

PLAT:

C6W10_21650

PRY:	Prubr_62850(rifN)

» show all

Reference

1 [PMID:12207505]

Authors

Arakawa K, Muller R, Mahmud T, Yu TW, Floss HG

Title

Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate.

Journal

J Am Chem Soc 124:10644-5 (2002)
DOI:10.1021/ja0206339

Sequence

[amn:RAM_03220]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.179

IUBMB Enzyme Nomenclature:

2.7.1.179

ExPASy - ENZYME nomenclature database:

2.7.1.179

BRENDA, the Enzyme Database:

2.7.1.179

DBGET integrated database retrieval system