KEGG ENZYME: 2.7.1.209

ENZYME: 2.7.1.209

Entry

EC 2.7.1.209                Enzyme

Name

L-erythrulose 1-kinase;
lerK (gene name);
L-erythrulose 1-kinase [incorrect]

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ATP:L-erythrulose 1-phosphotransferase

Reaction(IUBMB)

ATP + L-erythrulose = ADP + L-erythrulose 1-phosphate [RN:R11460]

Reaction(KEGG)

R11460

Substrate

ATP [CPD:C00002];
L-erythrulose [CPD:C02045]

Product

ADP [CPD:C00008];
L-erythrulose 1-phosphate [CPD:C03394]

Comment

The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol.

History

EC 2.7.1.209 created 2016, modified 2018

Orthology

K20901

L-erythrulose 1-kinase

Genes

MSM:	MSMEG_6788

MSG:	MSMEI_6605

MSB:	LJ00_33540

MSN:	LI99_33545

MSH:	LI98_33550

MPHL:

MPHLCCUG_03582(dhaK_2)

MLL:	B1R94_28270

MAUU:

NCTC10437_05455(dhaK_3)

MTY:	MTOK_43860(lerK_2)

MARZ:

MARA_39700(lerK)

MSEI:

MSEDJ_10910(lerK)

MGO:	AFA91_05905

CHAD:

CHAD_12355(dhaK)

SHAU:

K9S39_14815

AAGI:

NCTC2676_1_00197(dhaK_2)

ASUN:

KG104_17295

AZX:	N2K95_15885

KRS:	EQG70_16775

BCV:

Bcav_1547

BFA:	Bfae_00540

BRX:	BH708_13630

BGG:	CFK41_17150

BSAU:

DWV08_14415

BRR:	C1N80_02500

BKI:	M4486_12045 M4486_14600

BRHA:

NLU66_01540 NLU66_02710

BHH:	Bra3105_09105 Bra3105_11650

HMM:	R3I40_09175

PFR:	PFREUD_22470(dhaK_dhaL)

PFRE:

RM25_2127

PACD:

EGX94_08915

PAUS:

NCTC13651_02078(dhaK_2)

PROP:

QQ658_05285

BROO:

brsh051_27180

SNAH:

OUQ99_21630

SVI:	Svir_28690

TPY:	CQ11_09095

TPYO:

X956_09105

TPEC:

HLG82_08300

TBER:

QPC17_07520

ATIM:

CYJ17_0001100

AUO:	R3I39_00675

VCB:	CYK25_007840

» show all

Reference

1 [PMID:26560079]

Authors

Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA

Title

A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.

Journal

J Am Chem Soc 137:14570-3 (2015)
DOI:10.1021/jacs.5b08968

Sequence

[msm:MSMEG_6788]

Reference

2 [PMID:26978037]

Authors

Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA

Title

Correction to "A General Strategy for the Discovery of Metabolic Pathways: D-Threitol, L-Threitol, and Erythritol Utilization in Mycobacterium smegmatis".

Journal

J Am Chem Soc 138:4267 (2016)
DOI:10.1021/jacs.6b01906

Sequence

[msm:MSMEG_6788]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.209

IUBMB Enzyme Nomenclature:

2.7.1.209

ExPASy - ENZYME nomenclature database:

2.7.1.209

BRENDA, the Enzyme Database:

2.7.1.209

All links

Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (52)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (46)   
   KEGG MGENES (5)   
Protein sequence (16)   
   UniProt (14)   
   SWISS-PROT (2)   
DNA sequence (30)   
   GenBank (16)   
   EMBL (14)   
Protein domain (4)   
   InterPro (4)   
All databases (107)   

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