KEGG ENZYME: 2.7.1.212

ENZYME: 2.7.1.212

Entry

EC 2.7.1.212                Enzyme

Name

alpha-D-ribose-1-phosphate 5-kinase (ADP)

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ADP:alpha-D-ribose-1-phosphate 5-phosphotransferase

Reaction(IUBMB)

ADP + alpha-D-ribose-1-phosphate = AMP + alpha-D-ribose 1,5-bisphosphate [RN:R11535]

Reaction(KEGG)

R11535

Substrate

ADP [CPD:C00008];
alpha-D-ribose 1-phosphate [CPD:C00620]

Product

AMP [CPD:C00020];
alpha-D-ribose 1,5-bisphosphate [CPD:C01151]

Comment

The enzyme, characterized from the archaeon Thermococcus kodakarensis, participates in an archaeal pathway for nucleoside degradation.

History

EC 2.7.1.212 created 2016

Pathway

ec00030

Pentose phosphate pathway

ec01100

Metabolic pathways

Orthology

K21056

alpha-D-ribose-1-phosphate 5-kinase (ADP)

Genes

MSZE:

MSZNOR_1095

PAQA:

K9V56_021215

MIWA:

SS37A_23590

SCYE:

R2B67_21140

SGJ:	IAG43_24455

PFU:

PF1886

PFI:

PFC_09155

PHO:	PH1845(PH1845)

PAB:	PAB0280(rbsk)

PYN:

PNA2_0442

PYA:	PYCH_00740

PYS:

Py04_1773

PYC:	TQ32_07520

TKO:

TK2029

TON:

TON_1488

TGA:	TGAM_0139(rbsK)

TSI:

TSIB_1368

TBA:	TERMP_01545

THE:

GQS_08055

THA:

TAM4_1362

THM:

CL1_1233

TLT:

OCC_07421

THS:

TES1_1540

TNU:

BD01_1953

TEU:

TEU_01625

TGY:	X802_04655

THV:	ADU37_CDS14320

TCH:	CHITON_2127

TPEP:

A0127_05090

TPIE:

A7C91_04835

TGG:	A3K92_08995

TCE:	A3L02_06755

TBS:	A3L01_08275

THH:	CDI07_07305

TSL:	A3L11_01645

TTD:	A3L14_10650

TPRF:

A3L09_00800

TRL:	A3L10_07680

TPAF:

A3L08_01380

THY:	A3L12_04075

TIC:	FH039_11860

TCQ:	TIRI35C_1976

THEM:

FPV09_09675

THEI:

K1720_09940

PPAC:

PAP_05980

» show all

Reference

1 [PMID:25822915]

Authors

Aono R, Sato T, Imanaka T, Atomi H

Title

A pentose bisphosphate pathway for nucleoside degradation in Archaea.

Journal

Nat Chem Biol 11:355-60 (2015)
DOI:10.1038/nchembio.1786

Sequence

[tko:TK2029]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.212

IUBMB Enzyme Nomenclature:

2.7.1.212

ExPASy - ENZYME nomenclature database:

2.7.1.212

BRENDA, the Enzyme Database:

2.7.1.212

DBGET integrated database retrieval system