Entry
Name
C7-cyclitol 7-kinase;
valC (gene name);
vldC (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:C7-cyclitol 7-phosphotransferase
Reaction(IUBMB)
(1) ATP + valienone = ADP + valienone 7-phosphate [RN:
R11234 ];
(2) ATP + validone = ADP + validone 7-phosphate [RN:
R11406 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the bacterium Streptomyces hygroscopicus var. jinggangensis, is involved in the biosynthesis of the antifungal agent validamycin A.
History
EC 2.7.1.214 created 2016
Pathway
ec00525 Acarbose and validamycin biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
» show all
Taxonomy
Reference
Authors
Minagawa K, Zhang Y, Ito T, Bai L, Deng Z, Mahmud T
Title
ValC, a new type of C7-Cyclitol kinase involved in the biosynthesis of the antifungal agent validamycin A.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 2.7.1.214