KEGG   ENZYME: 2.7.1.230
Entry
EC 2.7.1.230                Enzyme                                 
Name
amicoumacin kinase;
amiN (gene name);
yerI (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:amicoumacin A 2-phosphotransferase
Reaction(IUBMB)
ATP + amicoumacin A = ADP + amicoumacin A 2-phosphate [RN:R12530]
Reaction(KEGG)
R12530
Substrate
ATP [CPD:C00002];
amicoumacin A [CPD:C22231]
Product
ADP [CPD:C00008];
amicoumacin A 2-phosphate [CPD:C22232]
Comment
The enzyme, found in some bacterial species, inactivates the antibiotic amicoumacin A by phosphorylating it, conferring resistance on the bacteria.
History
EC 2.7.1.230 created 2019
Orthology
K23983  amicoumacin kinase
Genes
MXA: MXAN_1793
MSD: MYSTI_02142
MYM: A176_002486
MFB: MFUL124B02_26845
MYX: QEG98_10025
CCX: COCOR_03490(yerI)
MFU: LILAB_30205
MMAS: MYMAC_004330
BSU: BSU06640(yerI)
BSR: I33_0753
BSL: A7A1_3129
BSH: BSU6051_06640(yerI)
BSY: I653_03315
BSUT: BSUB_00735(yerI)
BSUL: BSUA_00735(yerI)
BSUS: Q433_03765
BSO: BSNT_07043(yerI)
BSN: BSn5_15225
BSQ: B657_06640(yerI)
BSX: C663_0688(yerI)
BSP: U712_03360
BSS: BSUW23_03370(yerI)
BST: GYO_0926
BIT: BIS30_13935
BAY: RBAM_007040
BAQ: BACAU_0675(yerI)
BYA: BANAU_0620(yerI)
BAMP: B938_03270
BQY: MUS_0681(yerI)
BAML: BAM5036_0625(yerI)
BAMA: RBAU_0683(yerI)
BAMN: BASU_0655(yerI)
BAMB: BAPNAU_0631(yerI)
BAMT: AJ82_03930
BAMY: V529_06300(yerI)
BMP: NG74_00692(thrB_1)
BAO: BAMF_0659(yerI)
BAZ: BAMTA208_03100(yerI)
BQL: LL3_00708(yerI)
BXH: BAXH7_00652(yerI)
BAMI: KSO_016250
BAMC: U471_06780
BAMF: U722_03500
BSIA: CWD84_18500
BAE: BATR1942_00855
BVM: B9C48_03500
BHT: DIC78_06515
BMOJ: HC660_07030(yerI)
BTEQ: G4P54_03605
BIQ: AN935_03480
BSTR: QI003_03710
BAN: BA_0637
BAR: GBAA_0637
BAT: BAS0604
BAH: BAMEG_3950
BAI: BAA_0719
BAX: H9401_0608
BANT: A16_06980
BANR: A16R_07040
BANS: BAPAT_0614
BANH: HYU01_03445
BANV: DJ46_5095
BCE: BC0637
BCA: BCE_0705
BCZ: BCE33L0548
BCR: BCAH187_A0766
BCB: BCB4264_A0672
BCU: BCAH820_0693
BCG: BCG9842_B4665
BCQ: BCQ_0705
BCX: BCA_0675
BAL: BACI_c06500
BNC: BCN_0614
BCF: bcf_03275
BCER: BCK_04970
BTK: BT9727_0548
BTL: BALH_0578
BTB: BMB171_C0559
BTT: HD73_0712
BTHR: YBT1520_03535
BTHI: BTK_03640
BTC: CT43_CH0557
BTF: YBT020_03445
BTM: MC28_5365
BTG: BTB_c06510(yerI1)
BTI: BTG_17970
BTHT: H175_ch0563
BTHU: YBT1518_03355
BTW: BF38_1884
BTHY: AQ980_27415
BWE: BcerKBAB4_0550
BWW: bwei_4961(yerI)
BMYO: BG05_5284
BTY: Btoyo_3316
BMYC: DJ92_3239
BBY: CY96_02340
BWD: CT694_03605
BTRO: FJR70_25445
BMOB: MLA2C4_03370
BNT: GSN03_03490
BPAC: LMD38_22880
BPAN: NLJ82_03415
BALU: QRY64_05530
BPU: BPUM_0640
BPUM: BW16_03450
BPUS: UP12_03555
BIF: N288_08435 N288_24550
BXI: BK049_04665
BALT: CFN77_03425
BAER: BAE_10965
BSAF: BSL056_03370
BCAB: EFK13_03865
BRY: M0696_03785
BJS: MY9_0754
BACW: QR42_03365
BACP: SB24_06340
BACB: OY17_06160
BACY: QF06_02245
BACL: BS34A_07610(thrB_1)
BALM: BsLM_0696
BACS: AUL54_07270
BACQ: DOE78_07100
BZH: NF868_02915
BHAI: KJK41_06645
BARD: QRY57_05015 QRY57_15050
BAEI: RE735_15965
BCOH: BC6307_24045
SHUA: PQ477_12745
BGI: BGM20_18485
BON: A361_08500
CSUA: IM538_02955
CFIR: NAF01_08010
CSPG: LS684_06990
CPSS: M5V91_13105
BDA: FSZ17_08770
LSP: Bsph_2648
HNZ: P9989_18480
HAMY: MUO15_17130
VIG: BKP57_12495
VPT: KBP50_02095
FAR: ABE41_007365
FEC: QNH15_01025
BSJ: UP17_20860
BMUR: ABE28_020000
PBUT: DTO10_22445
PFRI: L8956_21685
AQT: FN924_05500
RAX: KO561_05710
PSYO: PB01_00565
PSYB: KD050_11455
PCHU: QNI29_06775
NMK: CHR53_14005
NDT: L1999_07685
NNV: QNH39_14655
AIA: AWH56_002300
BVQ: FHE72_07040
RMF: D5E69_07705
RAZ: U9J35_07050
BVJ: I5776_04900
BOU: I5818_06265
MCUI: G8O30_14870
GAJ: MY490_02340 MY490_17770
ECTO: MUG87_00800
ALKL: MM271_07155
PHJ: LC071_16335
GYM: GYMC10_0475 GYMC10_3193
PSAB: PSAB_04005 PSAB_16275
PBD: PBOR_21940
POD: PODO_17960
PAEN: P40081_01660 P40081_10140 P40081_22330
PAEF: R50345_14690 R50345_18120
PAEQ: R50912_20615
PAEJ: H70737_09640 H70737_14040 H70737_18075
PBJ: VN24_13905
PIH: UB51_10380
PRI: PRIO_2076
PXL: BS614_02725
PSWU: SY83_21320
PDH: B9T62_08840
PIB: BBD41_12295
PVO: PVOR_04688
PLW: D5F53_27160
PPSC: EHS13_15055 EHS13_30470
PBK: Back11_16110(yerI_1) Back11_45580(yerI_2) Back11_56180(yerI_4)
PBAC: HUB98_28850
PRZ: GZH47_23205
PLYC: GXP70_23235
PSOP: KP014_18195
PCEL: HUB94_10725
PTJ: JRJ22_17140
PALR: HGI30_03565
PMAH: PTQ21_21915 PTQ21_29155
PDY: QJQ58_02610
PSPN: L1F29_27760 L1F29_27965
PPOG: QPK24_10675 QPK24_11275
PAUN: MJA45_04330 MJA45_18675 MJA45_25655
PPAB: KET34_13350 KET34_26355
TAB: CIG75_10295
JEO: JMA_05550
LFB: C1X05_01985 C1X05_08565
TVU: AB849_003240
KEB: GXN75_10430
CBB: CLD_3202
CCB: Clocel_4319
CARG: RSJ17_06800
CMAH: C1I91_15995
ACEL: acsn021_16260(yerI)
TIZ: RBU61_06995
MBJ: KQ51_00770
TBK: HF295_07870
ACIT: HPK19_20590
PBF: CFX0092_A0025
DMB: E5F05_07370
GFM: Enr17x_13070
STR: Sterm_2566
LOB: NEF87_002388 NEF87_003356
 » show all
Reference
1  [PMID:30181282]
  Authors
Terekhov SS, Smirnov IV, Malakhova MV, Samoilov AE, Manolov AI, Nazarov AS, Danilov DV, Dubiley SA, Osterman IA, Rubtsova MP, Kostryukova ES, Ziganshin RH, Kornienko MA, Vanyushkina AA, Bukato ON, Ilina EN, Vlasov VV, Severinov KV, Gabibov AG, Altman S
  Title
Ultrahigh-throughput functional profiling of microbiota communities.
  Journal
Proc Natl Acad Sci U S A 115:9551-9556 (2018)
DOI:10.1073/pnas.1811250115
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.230
IUBMB Enzyme Nomenclature: 2.7.1.230
ExPASy - ENZYME nomenclature database: 2.7.1.230
BRENDA, the Enzyme Database: 2.7.1.230

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Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (271)   
   KEGG ORTHOLOGY (1)   
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   KEGG MGENES (33)   
Protein sequence (15)   
   UniProt (5)   
   SWISS-PROT (1)   
   PDBSTR (9)   
3D Structure (5)   
   PDB (5)   
Protein domain (3)   
   InterPro (3)   
All databases (299)   

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