KEGG   ENZYME: 2.7.1.232
Entry
EC 2.7.1.232                Enzyme                                 
Name
levoglucosan kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:1,6-anhydro-beta-D-glucopyranose 6-phosphotransferase (hydrolyzing)
Reaction(IUBMB)
ATP + levoglucosan + H2O = ADP + D-glucose 6-phosphate [RN:R12746]
Reaction(KEGG)
R12746
Substrate
ATP [CPD:C00002];
levoglucosan [CPD:C22350];
H2O [CPD:C00001]
Product
ADP [CPD:C00008];
D-glucose 6-phosphate [CPD:C00092]
Comment
Levoglucosan is formed from the pyrolysis of carbohydrates such as starch and cellulose and is an important molecular marker for pollution from biomass burning. The enzyme, found in yeast and fungi, requires a magnesium ion. cf. EC 1.1.1.425, levoglucosan dehydrogenase.
History
EC 2.7.1.232 created 2021
Orthology
K25043  levoglucosan kinase
Genes
PIC: PICST_36132
PGU: PGUG_04600
SLB: AWJ20_2341
NCR: NCU06383
NTE: NEUTE1DRAFT108710(NEUTE1DRAFT_108710)
TMN: UCRPA7_1136
SSCK: SPSK_09294
FPOA: FPOAC1_004043
FOX: FOXG_14970
FFC: NCS54_00367300
FKR: NCS57_00372500
TRE: TRIREDRAFT_5614 TRIREDRAFT_67642
TRR: M419DRAFT_11892 M419DRAFT_80113
MAJ: MAA_07772
PCHM: VFPPC_02481
PLJ: VFPFJ_02025
PTKZ: JDV02_002003 JDV02_003925
VAL: VDBG_09018
VDA: VDAG_10459
SAPO: SAPIO_CDS8834
ELA: UCREL1_4330
PSCO: LY89DRAFT_609597
ANI: ANIA_03499
AFM: AFUA_4G14600
NFI: NFIA_014600 NFIA_101770
AOR: AO090103000264
ANG: An05g02500
AFV: AFLA_013261
ALUC: AKAW2_81384A
ACHE: ACHE_10215A ACHE_30518A
APUU: APUU_10004A APUU_40148S APUU_40640S
PCS: N7525_001691
PDP: PDIP_36080
TRG: TRUGW13939_08486
AALT: CC77DRAFT_1019273
ZTR: MYCGRDRAFT_84209
NPA: UCRNP2_1025
 » show all
Reference
1  [PMID:12356473]
  Authors
Zhuang X, Zhang H.
  Title
Identification, characterization of levoglucosan kinase, and cloning and expression of levoglucosan kinase cDNA from Aspergillus niger CBX-209 in Escherichia coli.
  Journal
Protein Expr Purif 26:71-81 (2002)
DOI:10.1016/s1046-5928(02)00501-6
Reference
2
  Authors
Dai, J., Yu, Z., He, Y., Zhang, L., Bai, Z., Dong, Z., Du, Y. and Zhang, H.
  Title
Cloning of a novel levoglucosan kinase gene from Lipomyces starkeyi and its expression in Escherichia coli.
  Journal
World J Microbiol Biotechnol 25:1589-1595 (2009)
Reference
3  [PMID:21719279]
  Authors
Layton DS, Ajjarapu A, Choi DW, Jarboe LR.
  Title
Engineering ethanologenic Escherichia coli for levoglucosan utilization.
  Journal
Bioresour Technol 102:8318-22 (2011)
DOI:10.1016/j.biortech.2011.06.011
  Sequence
[ag:ACE79748]
Reference
4  [PMID:26433384]
  Authors
Islam ZU, Zhisheng Y, Hassan el B, Dongdong C, Hongxun Z.
  Title
Microbial conversion of pyrolytic products to biofuels: a novel and sustainable approach toward second-generation biofuels.
  Journal
J Ind Microbiol Biotechnol 42:1557-79 (2015)
DOI:10.1007/s10295-015-1687-5
Reference
5  [PMID:26354439]
  Authors
Bacik JP, Klesmith JR, Whitehead TA, Jarboe LR, Unkefer CJ, Mark BL, Michalczyk R.
  Title
Producing glucose 6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion.
  Journal
J Biol Chem 290:26638-48 (2015)
DOI:10.1074/jbc.M115.674614
  Sequence
[ag:ACE79748]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.232
IUBMB Enzyme Nomenclature: 2.7.1.232
ExPASy - ENZYME nomenclature database: 2.7.1.232
BRENDA, the Enzyme Database: 2.7.1.232

  All links  
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (46)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (45)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   InterPro (2)   
All databases (57)   

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