KEGG ENZYME: 2.7.1.237

ENZYME: 2.7.1.237

Entry

EC 2.7.1.237                Enzyme

Name

GTP-dependent dephospho-CoA kinase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

GTP:3'-dephospho-CoA 3'-phosphotransferase

Reaction(IUBMB)

GTP + 3'-dephospho-CoA = GDP + CoA [RN:R12608]

Reaction(KEGG)

R12608

Substrate

GTP [CPD:C00044];
3'-dephospho-CoA [CPD:C00882]

Product

GDP [CPD:C00035];
CoA [CPD:C00010]

Comment

The enzyme, characterized from the archaeon Thermococcus kodakarensis, participates in a coenzyme A biosynthesis pathway. cf. EC 2.7.1.24, dephospho-CoA kinase.

History

EC 2.7.1.237 created 2022

Pathway

ec00770

Pantothenate and CoA biosynthesis

ec01100

Metabolic pathways

Orthology

K09735

GTP-dependent dephospho-CoA kinase

Genes

MJA:

MJ_0395

MFE:	Mefer_0874

MVU:	Metvu_1473

MFS:	MFS40622_0924

MIF:	Metin_1063

MJH:	JH146_1441

MESG:

MLAUSG7_0125

MESA:

MLASG1_1308

MIG:	Metig_1028

MMP:

MMP0442

MMQ:	MmarC5_1195

MMX:	MmarC6_0469

MMZ:	MmarC7_1439

MMD:

GYY_02285

MMAK:

MMKA1_04630

MMAO:

MMOS7_04580

MMAD:

MMJJ_05890

MAE:

Maeo_0282

MVN:	Mevan_1427

MVO:

Mvol_0003

MOK:	Metok_0224

METF:

CFE53_03730

MTH:

MTH_266

MMG:	MTBMA_c07160

MWO:	MWSIV6_0682

MTEE:

MTTB_09090

METC:

MTCT_0229

METE:

tca_00246

METZ:

METMT2_0712

METK:

FVF72_00970

MTHM:

FZP57_03270

METJ:

FZP68_08275

MST:

Msp_0622

METB:

AW729_04485

MEIS:

PXD04_06310

MRU:

mru_1479

MSI:

Msm_0195

MEB:

Abm4_0719

MMIL:

sm9_0851

MEYE:

TL18_06060

MOL:

YLM1_0979

MARO:

MarbSA_20540

METV:

K4897_01435

MEL:	Metbo_0600

MEW:	MSWAN_1762

METH:

MBMB1_1384

MFC:

BRM9_0610

MFI:	DSM1535_0592

MCUB:

MCBB_1627

MSUB:

BK009_05930

METN:

BK008_01475

METT:

CIT01_10250

METO:

CIT02_11055

MEME:

HYG87_00025

MFEG:

GCM10025860_27820

MFV:

Mfer_0440

MKA:

MK1453

AFU:

AF_1115

AFG:	AFULGI_00012120

APO:	Arcpr_0603

AVE:	Arcve_0850

AST:	Asulf_00085

FPL:

Ferp_2227

GAC:

GACE_0913

GAH:

GAH_01873

PFU:

PF0254

PFI:

PFC_00325

PHO:	PH1909(PH1909)

PAB:

PAB1106

PYN:

PNA2_0897

PYA:	PYCH_13340

PYS:

Py04_0405

PYC:	TQ32_01095

TKO:

TK1697

TON:

TON_1911

TGA:

TGAM_0501

TSI:

TSIB_0028

TBA:	TERMP_02014

THE:

GQS_05635

THA:

TAM4_775

THM:

CL1_0760

TLT:

OCC_01504

THS:

TES1_1964

TNU:

BD01_1507

TEU:

TEU_03975

TGY:	X802_06475

THV:	ADU37_CDS22000

TCH:	CHITON_0468

TPEP:

A0127_06760

TPIE:

A7C91_05570

TGG:	A3K92_06810

TCE:	A3L02_01610

TBS:	A3L01_00235

THH:	CDI07_00265

TSL:	A3L11_03960

TTD:	A3L14_01535

TPRF:

A3L09_09680

TRL:	A3L10_09930

TPAF:

A3L08_03370

THY:	A3L12_03260

TIC:	FH039_02330

TCQ:	TIRI35C_0264

THEM:

FPV09_07020

THEI:

K1720_03200

PPAC:

PAP_00780

MBA:	Mbar_A0283

MBY:	MSBRM_2670

MBW:	MSBRW_0713

MBAR:

MSBR2_2628

MBAK:

MSBR3_2797

MAC:

MA_3694

MMA:

MM_0598

MMAZ:

MmTuc01_0605

MMJ:	MSMAS_0711

MMAC:

MSMAC_0712

MVC:	MSVAZ_0652

MEK:	MSKOL_0630

MLS:	MSLAZ_2263

METM:

MSMTP_0914

MEF:	MSWH1_2401

MEQ:	MSWHS_2646

MSJ:	MSSAC_3524

MSZ:	MSSIH_3043

MSW:	MSSIT_3101

MTHR:

MSTHT_2418

MTHE:

MSTHC_0864

MHOR:

MSHOH_0826

MFZ:	AOB57_003335

MBU:

Mbur_2282

MMET:

MCMEM_0431

MELO:

J7W08_00185

MMH:

Mmah_0492

MHAZ:

BHR79_00965

MPOT:

BKM01_07445

MEV:	Metev_0570

MZH:	Mzhil_0482

MPY:

Mpsy_0973

MZI:	HWN40_03670

MMAV:

RE476_06545

MSEB:

RE474_01965

MHZ:	Metho_0556

MEHF:

MmiHf6_07910

MEES:

MmiEs2_03210

MTP:

Mthe_1323

MCJ:

MCON_3184

MHI:

Mhar_1913

MHU:

Mhun_2865

MRTJ:

KHC33_02625

MLA:

Mlab_0656

MEM:	Memar_2244

MBG:	BN140_1416

MEMA:

MMAB1_1818

MCHK:

MchiMG62_25630

MSUM:

OH143_05505

MRC:	R6Y96_03750

MPI:

Mpet_0093

MEND:

L6E24_07595

MEFW:

F1737_10535

MAQE:

RJ40_07105

MFK:	E2N92_07260

MOU:	OU421_07715

MESB:

L1S32_11100

MANQ:

L1994_10525

MBN:

Mboo_0243

MFO:	Metfor_2870

MPL:

Mpal_0601

MPD:

MCP_2673

MEZ:

Mtc_0179

RCI:

RCIX625

HSL:

OE_3871R

HANR:

LJ422_08240

HDL:	HALDL1_15130

HHB:

Hhub_3346

HAGS:

JT689_09590

HABO:

JRZ79_07970

HNO:	LT974_13540

HLU:	LT972_01210

HALH:

HTSR_1917

HHSR:

HSR6_1986

HSU:	HLASF_1983

HSF:	HLASA_1969

HAHS:

HSRCO_2629

SALR:

FQU85_05895

HALR:

EFA46_002695

HJE:	HacjB3_03895

HDO:	MUK72_04610

HALX:

M0R89_04295

HAXZ:

M0R88_04355

HAYC:

NGM10_10535

HAXY:

NGM07_10005

SALI:

L593_13905

SAIM:

K0C01_04525

HARA:

AArcS_2496

HMA:

rrnAC2831

HHI:

HAH_0110

HHN:	HISP_00625

HAB:	SG26_08490

HTA:	BVU17_00520

HALJ:

G9465_02065

HSIN:

KDQ40_12850

NPH:

NP_5076A

NMO:

Nmlp_1554

NHO:	HWV23_05775

NSAL:

HWV07_16765

HUT:

Huta_2205

HTI:

HTIA_2044

HALA:

Hrd1104_02720

HASV:

SVXHr_2373

HABN:

HBNXHr_2369

HMU:

Hmuk_0726

HALZ:

E5139_06810

HALL:

LC1Hm_3238

HAZP:

GBQ70_06805

HALI:

BV210_07700

HSN:	DV733_00525

HDS:	HSR122_2313

HRR:	HZS55_03015

HPEL:

HZS54_02690

HLT:	I7X12_09085

HARC:

HARCEL1_10780

SSAI:

N0B31_10710

HAAD:

MW046_09420

HWA:

HQ_1339A

HWC:

Hqrw_1400

HVO:

HVO_1897

HME:

HFX_1988

HGI:	ABY42_09205

HALE:

G3A49_12490

HLS:	KU306_03040

HLN:	SVXHx_2719(dpck)

HBO:	Hbor_05020

HAQ:	DU484_03485

HAJ:	DU500_03940

HAER:

DU502_01850

HRA:	EI982_11560

HLM:	DV707_13770

HALM:

FCF25_00870

HLA:

Hlac_2394

HALP:

DOS48_12120

HALB:

EKH57_13270

HEZZ:

EO776_13045

HALQ:

Hrr1229_008985

HSS:	J7656_03245

HSAI:

HPS36_08590

HAZZ:

KI388_11615

SRUB:

C2R22_17475

HAE:	halTADL_3267

HALN:

B4589_011490

HALG:

HUG10_10895

HALU:

HUG12_05260

HMP:	K6T50_09310

HRE:	K6T36_09085

HRM:	K6T25_06805

HACB:

Hbl1158_01230

HDF:	AArcSl_0228

HAH:	Halar_2725

HTU:

Htur_3456

HSAL:

JMJ58_11080

HAKZ:

J0X25_04995

NMG:

Nmag_1490

HXA:	Halxa_3489

NAT:

NJ7G_2519

NPE:	Natpe_0550

NVR:	FEJ81_03105

NPL:	FGF80_07815

NAY:	HYG81_07500

HALY:

HYG82_10240

HJT:	DVR14_11980

HLO:	J0X27_07220

NGE:	Natgr_2317

HRU:	Halru_2544

SAWL:

NGM29_00215

HALV:

NGM15_09780

NOU:	Natoc_2359

HLR:	HALLA_17910

HLC:	CHINAEXTREME07090

NAJ:	B1756_04160

NAG:	AArcMg_0257

NAN:	AArc1_0258

NARA:

QQ977_12230

NBG:	DV706_05115

NAS:	GCU68_08180

HDA:	BB347_15935

MELU:

MTLP_02990

MEAM:

MU439_04510

MEAE:

QEN48_05670

TAC:

Ta1091

TVO:	TVG0468984(TVG0468984)

PTO:

PTO0868

FAC:	FACI_IFERC01G1477

FAI:

FAD_0459

CDIV:

CPM_1268

TAR:	TALC_00505

MAX:	MMALV_04390

MER:	MMINT_07120

MEAR:

Mpt1_c03740

MEUZ:

KRP56_05870

MARC:

AR505_1372

ABI:

Aboo_0566

ACF:	AciM339_0483

APE:

APE_0256

ACJ:

ACAM_0194

SMR:

Smar_0835

SHC:	Shell_1632

IHO:

Igni_0082

IIS:

EYM_05595

DKA:

DKAM_1343

DFD:	Desfe_1439

DMU:	Desmu_1335

TAG:

Tagg_1373

IAG:

Igag_1897

THG:	TCELL_0550

HBU:

Hbut_0437

PFM:	Pyrfu_0254

PDL:	Pyrde_0121

PABI:

PABY_21890

PARE:

PYJP_19770

STO:

STK_03780

SOH:	D1869_01615

SSO:

SSO0416

SOL:

Ssol_1393

SSOA:

SULA_1439

SSOL:

SULB_1440

SSOF:

SULC_1438

SSHI:

J5U23_03020

SCAS:

SACC_06120

SAI:

Saci_0836

SACN:

SacN8_04055

SACR:

SacRon12I_04045

SACS:

SUSAZ_03790

SIS:	LS215_1816

SIA:	M1425_1688

SIM:	M1627_1804

SID:

M164_1735

SIY:	YG5714_1804

SIN:	YN1551_1122

SII:

LD85_1945

SIH:

SiH_1663

SIR:

SiRe_1584

SIC:

SiL_1576

SULA:

BFU36_03730

SULE:

GFS03_09485

SULO:

GFS33_01300

SULL:

EWF20_03085

MSE:

Msed_2239

MEMJ:

MJ1HA_2559

MCN:

Mcup_0069

MHK:	DFR87_07340

MPRU:

DFR88_07025

MTEN:

GWK48_04825

MJN:	MjAS7_0531

AHO:

Ahos_0710

AMAN:

B6F84_06985

ASUL:

DFR86_06045

AAMB:

D1866_11335

ACIH:

HS5_20840

SACD:

HS1genome_0341

SAZO:

D1868_02535

CSTY:

KN1_19950

STEP:

IC006_1511

SMET:

RQ359_000425

SAHS:

HS7_06830

PAI:

PAE3284

PIS:

Pisl_0494

PCL:

Pcal_1764

PAS:

Pars_1711

PYR:

P186_1323

POG:

Pogu_0423

TNE:

Tneu_1532

PYW:	PYWP30_01679

CMA:

Cmaq_1963

TTN:

TTX_0546

TUZ:

TUZN_0189

VDI:

Vdis_2228

VMO:

VMUT_0665

TPE:

Tpen_0578

THEL:

IG193_04965

ASC:

ASAC_1120

ACIA:

SE86_06740

CLG:	Calag_0421

FFO:	FFONT_0441

NMR:

Nmar_1233

NIR:	NSED_06915

NKR:	NKOR_06995

NID:	NPIRD3C_0878

NIN:	NADRNF5_0710

NIW:	Nisw_07555

NCL:	C5F47_06740

NOX:	C5F49_06715

NUE:	C5F50_09325

NIP:	NsoK4_01840

NZT:	NZOSNM25_000587

NCT:

NMSP_0442

NIC:	DSQ20_07700

NGA:	Ngar_c18380

NVN:	NVIE_003780

NEV:

NTE_01707

TAA:	NMY3_01470

NFN:	NFRAN_2364

NCV:

NCAV_0850

CSY:	CENSYa_0966

CSU:	CSUB_C0436

NBV:

T478_0497

TAH:	SU86_000050

NIU:	DSQ19_06935

NCK:	QVH35_11235

NDV:

NDEV_1216

CCAI:

NAS2_0370

KCR:

Kcr_1362

BARC:

AOA65_1090

BARB:

AOA66_1285

FLT:	Sv326_1062

LOKI:

Lokiarch_06350 Lokiarch_42000

LOB:	NEF87_001303

PSYT:

DSAG12_03403

» show all

Reference

1 [PMID:31337720]

Authors

Shimosaka T, Makarova KS, Koonin EV, Atomi H

Title

Identification of Dephospho-Coenzyme A (Dephospho-CoA) Kinase in Thermococcus kodakarensis and Elucidation of the Entire CoA Biosynthesis Pathway in Archaea.

Journal

mBio 10:e01146-19 (2019)
DOI:10.1128/mBio.01146-19

Sequence

[tko:TK1697]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.237

IUBMB Enzyme Nomenclature:

2.7.1.237

ExPASy - ENZYME nomenclature database:

2.7.1.237

BRENDA, the Enzyme Database:

2.7.1.237

All links

Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (2549)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (416)   
   KEGG MGENES (2132)   
Protein sequence (2569)   
   UniProt (2508)   
   SWISS-PROT (61)   
Protein domain (1)   
   InterPro (1)   
All databases (5131)   

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