KEGG ENZYME: 2.7.1.87

ENZYME: 2.7.1.87

Entry

EC 2.7.1.87                 Enzyme

Name

streptomycin 3''-kinase;
streptomycin 3''-kinase (phosphorylating);
streptomycin 3''-phosphotransferase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ATP:streptomycin 3''-phosphotransferase

Reaction(IUBMB)

ATP + streptomycin = ADP + streptomycin 3''-phosphate [RN:R02227]

Reaction(KEGG)

R02227

Substrate

ATP [CPD:C00002];
streptomycin [CPD:C00413]

Product

ADP [CPD:C00008];
streptomycin 3''-phosphate [CPD:C03731]

Comment

Also phosphorylates dihydrostreptomycin, 3'-deoxydihydrostreptomycin and their 6-phosphates.

History

EC 2.7.1.87 created 1976

Orthology

K10673

streptomycin 3"-kinase

Genes

EOI:	ECO111_p1-123

ECOO:

ECRM13514_5832(strA)

ESL:

O3K_00465

ESO:

O3O_25225

ESM:

O3M_00475

ECG:	E2348_P2_02(strA)

ELR:	ECO55CA74_26389

ECW:	EcE24377A_B0004

EUN:	pUMNK88_43(strA)

ECM:	EcSMS35_A0128(strA)

ELN:	NRG857_30096

EFE:	EFER_p0048

STY:	HCM1.223(strA)

SEY:	SL1344_P3_0014(aph(3'')-Ib)

SEM:	STMDT12_S00070

SEB:	STM474_p311(strA)

SETU:

STU288_2p00040

SEC:	SCH_065(stra)

SEH:	SeHA_C1570(strA)

SEE:	SNSL254_p_0046(strA)

SEW:	SeSA_B0085(strA)

SFE:

SFxv_5149

SSN:	SSON_PA04(strA)

ECLY:

LI62_012835

KPN:	KPN_pKPN5p08179(str)

KPM:	KPHS_p300870

KPG:	KPNIH32_27960

KPA:	KPNJ1_05662

KPX:	PMK1_c00069(neo)

KPB:	FH42_26490

KOK:	KONIH1_31680

KLL:	BJF97_29135

KLW:	DA718_21545(aph(3'')-Ib)

KGR:	JJJ10_28310(aph(3'')-Ib)

KPAS:

LUW96_29795(aph(3'')-Ib)

CFQ:	C2U38_26775

CFAR:

CI104_25745

CIR:	C2U53_02835

CITZ:

E4Z61_00215(aph(3'')-Ib)

KIN:	AB182_03140

PCOL:

F1325_16175(aph(3'')-Ib)

PCIB:

F9282_16440(aph(3'')-Ib)

PRQ:	CYG50_01295(aph(3'')-Ib)

ETR:

ETAE_p040

PMV:	PMCN06_p02(strA)

PMP:	Pmu_02770(strA)

MHX:	MHH_c22570(strA)

APA:	APP7_B0004(strA)

AIO:	EXH44_00900(aph(3'')-Ib)

BTO:

WQG_1050

BTRH:

F543_22810

BTRA:

F544_3110

XCV:	XCV2326(strA)

PMEX:

H4W19_04390(aph(3'')-Ib)

VCF:	IR04_08330

VCE:	Vch1786_I0085(strA)

VCQ:	EN18_05270 EN18_06330 EN18_06380

VCJ:	VCD_003731

VTU:	IX91_25360

PAEU:

BN889_06183

PPUH:

B479_26879

PPUT:

L483_16470

PSB:

Psyr_2669

PSES:

PSCI_1740

PJU:	L1P09_12585(aph(3'')-Ib) L1P09_25465

PHYG:

JTY93_27845(aph(3'')-Ib)

DCE:	O6P33_04945(aph(3'')-Ib)

ABY:	ABAYE3648(aphE)

ABX:	ABK1_0258 ABK1_0266

ABZ:	ABZJ_00266(aph(3'')-Ib)

ABR:	ABTJ_03558

ABD:	ABTW07_0269(strA)

ABH:

M3Q_482

ABJ:	BJAB07104_00282

ABAB:

BJAB0715_02891

ABAJ:

BJAB0868_00286

ABK:	LX00_17585

ABAU:

IX87_13230

ABAA:

IX88_03700

ABW:	BL01_17610

ABAL:

ABLAC_01120

AJO:	RZ95_17210

ASJ:	AsACE_p200017

ADV:	DJ533_07385(aph(3'')-Ib)

AWU:	BEN71_00445(aph(3'')-Ib)

ACUM:

C9E88_016485(aph(3'')-Ib)

AVB:	RYU24_23430

APOT:

MZO21_09755(aph(3'')-Ib) MZO21_13400(aph(3'')-Ib)

MBL:	AAX09_10055

SBJ:	CF168_22030

SALG:

BS332_22255

SHEJ:

MZ182_20705(aph(3'')-Ib)

RHH:	E0Z06_12440(aph(3'')-Ib)

ASIM:

FE240_15530(aph(3'')-Ib)

SINI:

GT972_03205(aph(3'')-Ib)

NSI:	A6J88_09480 A6J88_09535

KKI:	KKKWG1_0922(strA) KKKWG1_0930(strA)

CHIZ:

HQ393_17290(aph(3'')-Ib)

CHIC:

N8I74_07870

AALN:

Q3V95_09610(aph(3'')-Ib)

AAMM:

FE795_09100(aph(3'')-Ib)

VBO:	CKY39_20925

CKE:	B5M06_08240 B5M06_08385

DIH:	G7047_30130(aph(3'')-Ib)

SME:

SMc02722

SMK:	Sinme_2431

SMEL:

SM2011_c02722

SMD:

Smed_2292

SIX:

BSY16_877

ENU:	PYH37_004862

SKM:	PZL22_002715

ECAA:

J3R84_20340

ARUI:

G6M88_25935(aph(3'')-Ib)

RTR:	RTCIAT899_CH00745

RHR:	CKA34_03715

LNE:	FZC33_21375(aph(3''))

AALA:

IGS74_18415(aph(3''))

PSTG:

E8M01_25200(aph(3''))

BND:	KWG56_18550(aph(3'')-Ib)

PPAN:

ESD82_09490(aph(3'')-Ib)

PAEZ:

PAE61_06755

HML:	HmaOT1_07975(aph(3''))

SPHF:

DM480_17840

ROS:	CTJ15_23585

MYV:	G155_25620

MFT:	XA26_51950

MALV:

MALV_27290

MMAT:

MMAGJ_38700

MBOK:

MBOE_02270

MFG:	K6L26_26805

MGO:	AFA91_22730

MSEN:

K3U95_04860

MAB:

MAB_2385

MMV:	MYCMA_1289

MABB:

MASS_2303

MABL:

MMASJCM_2326

MCHE:

BB28_11930

MIZ:	BAB75_12855

MSTE:

MSTE_02320

MSAO:

MYCSP_11055

MSAL:

DSM43276_02103(neo_2)

CUR:	cu1538(strA)

CUA:	CU7111_1484

CII:	CIMIT_00695

CSX:	CSING_01990

CCJZ:

ccrud_14575 ccrud_14660 ccrud_14720

CKW:	CKALI_00250(neo)

CWK:	IA203_04655(aph(3''))

CHAD:

CHAD_02595(neo2)

CPYR:

CYJ47_11080(aph(3'')-Ib)

NTP:	CRH09_23805

NGP:	LTT66_05435

NSPU:

IFM12276_50560

SALB:

XNR_3279

SGR:	SGR_249(aphE)

SANL:

KZO11_37345

SBH:

SBI_00203

SCW:	TU94_25875

STRC:

AA958_20680

SLE:	sle_16300(sle_16300)

SKY:	D0C37_15000(aph(3''))

SGM:	GCM10017557_72430

STRD:

NI25_18235

SNW:	BBN63_23160

SNK:	CP967_14435(aph(3''))

SBY:	H7H31_13685(aph(3''))

SRIM:

CP984_39265(aph(3''))

SSUB:

CP968_28715(aph(3''))

SDW:	K7C20_03765

SGJ:	IAG43_00945(aph(3''))

SINE:

KI385_00710

SRUG:

F0345_00310(aph(3''))

SVIO:

HWN34_16775(aph(3''))

SXT:	KPP03845_100480(neo)

SANT:

QR300_18285

SLAI:

P8A22_01150

STRZ:

OYE22_13475

YIA:	LO772_01800

MRN:	K8F61_16810

MHUM:

NNL39_12905

CET:	B8281_00310

CCEU:

CBR64_11750

CPRT:

FIC82_018260

TFL:	RPIT_14600

PRV:	G7070_05965(aph(3''))

KFL:

Kfla_3320

KSL:	OG809_17425

SAIU:

J4H86_03315

SRO:	Sros_3941 Sros_6646

SACG:

FDZ84_30065(aph(3''))

AMYB:

BKN51_20195

APRE:

CNX65_09940

KPHY:

AOZ06_22725

PMAD:

BAY61_21060

CROS:

N8J89_27960

MTUA:

CSH63_22030

ASER:

Asera_24060

PRY:	Prubr_44840

SNA:

Snas_4099

STUC:

G5S47_08030(aph(3'')-Ib)

CHF:	KTO58_23810

» show all

Reference

1 [PMID:4121456]

Authors

Walker JB, Skorvaga M.

Title

Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives.

Journal

J Biol Chem 248:2435-40 (1973)

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.87

IUBMB Enzyme Nomenclature:

2.7.1.87

ExPASy - ENZYME nomenclature database:

2.7.1.87

BRENDA, the Enzyme Database:

2.7.1.87

CAS:	39391-15-6

DBGET integrated database retrieval system