KEGG ENZYME: 2.7.3.13

ENZYME: 2.7.3.13

Entry

EC 2.7.3.13                 Enzyme

Name

glutamine kinase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a nitrogenous group as acceptor

Sysname

ATP:L-glutamine N5-phosphotransferase

Reaction(IUBMB)

ATP + L-glutamine + H2O = AMP + phosphate + N5-phospho-L-glutamine [RN:R11941]

Reaction(KEGG)

R11941

Substrate

ATP [CPD:C00002];
L-glutamine [CPD:C00064];
H2O [CPD:C00001]

Product

AMP [CPD:C00020];
phosphate [CPD:C00009];
N5-phospho-L-glutamine [CPD:C21785]

Comment

The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.

History

EC 2.7.3.13 created 2017

Orthology

K22424

glutamine kinase

Genes

PROD:

PCO85_05450

DDC:	Dd586_1831

TAMN:

N4264_24350

VAF:	D1115_22860

PMK:

MDS_1828

PPU:

PP_0728

PPB:	PPUBIRD1_0774

PPUT:

L483_03695 L483_03700

PPUD:

DW66_0747

PMON:

X969_02150

PMOT:

X970_02130

PALD:

LU682_003960

PFO:	Pfl01_5512

PRX:	HRH33_09100

PCH:	EY04_30530

PCZ:	PCL1606_01900

PCP:	JM49_01210

PCHP:

C4K32_6097

PLQ:	AA042_05475

PSEM:

TO66_30415

PFIT:

KJY40_29490

PASI:

LG197_09075

PHOM:

KJF94_05595

PCHE:

QYM18_22770

MHC:

MARHY0657

SPL:

Spea_1404

AGZ:	M0C34_07890

MMT:	Metme_1177

TZO:	THMIRHAT_08540

HHA:

Hhal_0771

HHK:	HH1059_03570

OME:	OLMES_3127

AHA:

AHA_4154

AHH:	RY45_21640

AEO:	O23A_p3861

ADH:	CK627_03025

THO:	SP60_02260

CHIC:

N8I74_10215

CTI:	pRALTA_0398

BBRO:

BAU06_24700

ACHR:

C2U31_03835

ACHB:

DVB37_27195

CDN:	BN940_10771

OTR:	OTERR_09340

REN:	EF513_06960

AVV:	RvVAT039_pl03320

AVI:	Avi_7106 Avi_7108

MLD:	U0023_28240

RPEL:

N7U68_00615

PAED:

G5B38_20030

ALI:	AZOLI_p60024

ATI:	AL072_31790

AZM:	DM194_26725

MGY:	MGMSRv2__3405

MAGX:

XM1_2455

THAR:

T8K17_08580

PEL:	SAR11G3_00124 SAR11G3_00125

HHE:

HH_1436

HCP:

HCN_1067

HCB:	HCBAA847_0908

HBL:	XJ32_09975

HAD:	CDV25_08800

HCL:	NCTC13205_00569

HPUL:

NCTC13154_00542

WSU:

WS2180

CJE:

Cj1418c

CJB:	BN148_1418c

CJJ:	CJJ81176_1417

CJU:

C8J_0639

CJI:

CJSA_1349

CJM:

CJM1_0657

CJP:	A911_06900

CJEJ:

N564_01415

CJEU:

N565_01455

CJEN:

N755_01452

CJEI:

N135_01507

CJER:

H730_08045

CJV:	MTVDSCj20_0696

CJY:	QZ67_01553

CJQ:

UC78_1360

CJW:	PJ18_07245

CJD:	JJD26997_1751

CJZ:	M635_02765

CJX:	BN867_06860

CFF:	CFF8240_1630

CFT:	CFF04554_1632

CFV:	CFVI03293_1654

CFX:	CFV97608_1757

CFZ:

CSG_17640

CAMP:

CFT03427_1582

CFP:	CR44_08040

CLA:

CLA_0314

CLN:	UPTC3659_1407

CLL:	CONCH_1264

CCOL:

BN865_14280

CCF:

YSQ_05940

CCY:

YSS_03100

CCOI:

YSU_05590

CIS:

CINS_0304

CSM:	CSUB8521_0346

CSF:	CSUB8523_0328

CHV:	CHELV3228_1343

CCUN:

CCUN_1305

CUX:	CUP3940_0677

CINF:

CINF_1339

CNV:	CNZW441b_1099

CVU:	CVULP_0994

GLO:

Glov_3394

DSD:	GD606_13310

DVM:

DvMF_0014

CLIH:

KPS_000025

DOA:	AXF15_00620

CCX:	COCOR_06829

MAI:

MICA_1012

PAEE:

R70331_05225

PIH:	UB51_00295

BPEN:

NQ488_04910

COO:

CCU_12650

CEV:	LK421_10970

WCP:	H9Q76_08750

SGZ:	C0216_11010

KQI:	F1D05_10785

AACD:

LWP59_19220

LED:	BBK82_30185

PMAD:

BAY61_25150

PMF:	P9303_29441

FPOL:

ERS445057_00337

NVA:	G3M78_01015

SAIM:

K0C01_02805

NPH:

NP_1948A

HALY:

HYG82_02850

NAJ:	B1756_14540

NMR:

Nmar_0660

NIW:	Nisw_04320

NUE:	C5F50_00565

» show all

Reference

1 [PMID:28650156]

Authors

Taylor ZW, Brown HA, Narindoshvili T, Wenzel CQ, Szymanski CM, Holden HM, Raushel FM

Title

Discovery of a Glutamine Kinase Required for the Biosynthesis of the O-Methyl Phosphoramidate Modifications Found in the Capsular Polysaccharides of Campylobacter jejuni.

Journal

J Am Chem Soc 139:9463-9466 (2017)
DOI:10.1021/jacs.7b04824

Sequence

[cje:Cj1418c]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.3.13

IUBMB Enzyme Nomenclature:

2.7.3.13

ExPASy - ENZYME nomenclature database:

2.7.3.13

BRENDA, the Enzyme Database:

2.7.3.13

DBGET integrated database retrieval system