KEGG ENZYME: 2.7.7.68

ENZYME: 2.7.7.68

Entry

EC 2.7.7.68                 Enzyme

Name

2-phospho-L-lactate guanylyltransferase;
cofC (gene name) (ambiguous)

Class

Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases

Sysname

GTP:2-phospho-L-lactate guanylyltransferase

Reaction(IUBMB)

(2S)-2-phospholactate + GTP = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate [RN:R09397]

Reaction(KEGG)

R09397

Substrate

(2S)-2-phospholactate [CPD:C19156];
GTP [CPD:C00044]

Product

(2S)-lactyl-2-diphospho-5'-guanosine [CPD:C19155];
diphosphate [CPD:C00013]

Comment

This enzyme is involved in the biosynthesis of coenzyme F420, a redox-active cofactor, in all methanogenic archaea. cf. EC 2.7.7.105, phosphoenolpyruvate guanylyltransferase and EC 2.7.7.106, 3-phospho-(R)-glycerate guanylyltransferase.

History

EC 2.7.7.68 created 2010, revised 2019, modified 2020

Pathway

ec00680

Methane metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K14941

2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase

Genes

VAQ:	FIV01_04150(cofC)

PPHA:

BVH74_17770

CPS:

CPS_4046

ALT:	ambt_18405

ASP:	AOR13_3371

MAGA:

Mag101_11130

MPC:	Mar181_0281

MPRI:

MP3633_0355(cofC)

MFOI:

JSY38_07515(cofC)

MRHI:

KDW99_18320(cofC)

MPON:

MACH16_28790

MARS:

A8C75_03580

MRZ:	KDW95_12765(cofC)

ASIM:

FE240_15075

SDF:	ACG33_10260

BPY:	Bphyt_4254

PSPW:

BJG93_33625(cofC)

BRH:	RBRH_02550

APES:

FOC84_15070(cofC)

PUD:	G9Q38_02365(cofC)

DOE:	DENOEST_1244 DENOEST_3710(cofC)

EBA:

p2A342

AZI:	AzCIB_1482

AZD:	CDA09_09835(cofC)

THU:	AC731_008660

TAK:	Tharo_0193

ANJ:	AMD1_0563(fbiD)

SMEG:

C770_GR4pC0060

SMER:

DU99_18235

ARUI:

G6M88_23515(cofC)

KAI:	K32_16300(cofC)

OCL:	GTN27_07115

BIC:	LMTR13_24635

BRK:	CWS35_20195(cofC)

BQB:	J4P68_0009785(cofC)

BRAZ:

LRP30_33425(cofC)

RPB:

RPB_4422

OCA:

OCAR_5006

OCG:	OCA5_c29520

STAR:

G3545_06895(cofC)

LNE:	FZC33_07435(cofC)

SNO:

Snov_4231

APRA:

G3A50_17785(cofC)

MOG:	MMB17_16625(cofC)

HMC:	HYPMC_3548

RHZ:	RHPLAN_54340

METG:

HT051_05465(cofC)

BVR:

BVIR_2252

BLAG:

BLTE_05740

RBM:

TEF_20095

PSF:

PSE_2790

CAUL:

KCG34_11240(cofC)

PZU:

PHZ_c2537

LMD:	METH_04440

LAQU:

R2C4_00565(cofC)

LCAE:

K3721_20510(cofC)

PDE:

Pden_1117

PALP:

JHW40_21080(cofC)

RMB:	K529_001410

THAS:

C6Y53_09630(cofC)

LVR:	T8T21_14995(cofC)

NRE:	BES08_02695 BES08_26715

NOV:	TQ38_007730(cofC)

SPHO:

C3E99_13150(cofC)

SPHU:

SPPYR_1434(cofC)

SWI:

Swit_0413

SPHD:

HY78_26030

RDI:	CMV14_13685(cofC)

SBIN:

SBA_ch2_1020(cofC)

SNAP:

PQ455_18155(cofC)

SCH:	Sphch_2204

SYB:	TZ53_04415

SBD:	ATN00_13430

SPMI:

K663_16410

SPHB:

EP837_01486(cofC)

SPHT:

K426_20940

SHYD:

CJD35_15470(cofC)

SYA:	A6768_05860(cofC)

SCLO:

SCLO_1006410

SUFL:

FIL70_11575(cofC) FIL70_15535(cofC)

SBAR:

H5V43_13875(cofC)

SPPH:

KFK14_07115(cofC)

BLAS:

BSY18_2467

SPHJ:

BSL82_04915 BSL82_08900

CMAN:

A9D14_14820

NTD:	EGO55_02485(cofC)

KHA:	IFJ82_10830(cofC)

PAUU:

E8A73_035585(cofC)

ERZ:	ER308_05190(cofC)

EUZ:	DVS28_a3473

MTU:

Rv2983

MTV:

RVBD_2983

MTC:

MT3061

MRA:

MRA_3012

MTF:	TBFG_12998

MTB:	TBMG_00986

MTK:	TBSG_00993

MTZ:	TBXG_000977

MTG:	MRGA327_18345

MTI:	MRGA423_18545

MTE:	CCDC5079_2739

MTUR:

CFBS_3146

MTL:	CCDC5180_2704

MTO:	MTCTRI2_3042

MTD:

UDA_2983

MTN:	ERDMAN_3269

MTJ:	J112_15970

MTUB:

MT7199_3019

MTUC:

J113_20790

MTUE:

J114_15935

MTX:	M943_15365

MTUH:

I917_20945

MTUL:

TBHG_02913

MTUT:

HKBT1_3133

MTUU:

HKBT2_3138

MTQ:	HKBS1_3140

MBO:	BQ2027_MB3007

MBB:

BCG_3004

MBT:

JTY_2999

MBM:	BCGMEX_3000

MBK:	K60_030930

MBX:

BCGT_2823

MAF:

MAF_29880

MMIC:

RN08_3292

MCE:	MCAN_30051

MCQ:	BN44_60466

MCV:	BN43_40691

MCX:	BN42_40987

MCZ:	BN45_51397

MORY:

MO_003119(cofC)

MLE:

ML1680

MLB:

MLBr01680

MPA:

MAP_3021

MAO:

MAP4_0779

MAVI:

RC58_03820

MAVU:

RE97_03825

MIT:

OCO_36520

MIA:

OCU_36560

MID:

MIP_05522

MYO:

OEM_37160

MCHI:

AN480_19300

MIR:

OCQ_37720

MMAL:

CKJ54_17295(cofC)

MLP:

MLM_3043

MMAN:

MMAN_01300(cofC)

MSA:	Mycsm_02262

MUL:

MUL_1973

MMI:

MMAR_1731

MMAE:

MMARE11_16500

MLI:	MULP_01887(cofC)

MPSE:

MPSD_41090(cofC)

MSHO:

MSHO_55140(cofC)

MMC:

Mmcs_1926

MKM:

Mkms_1972

MJL:

Mjls_1906

MMM:

W7S_18275

MKN:	MKAN_23645

MYV:	G155_11510

MYE:	AB431_10485

MHAD:

B586_15605

MDX:	BTO20_23385

MSHG:

MSG_01590(cofC)

MFJ:	MFLOJ_17150(cofC)

MSTO:

MSTO_18810(cofC)

MSIM:

MSIM_08140(cofC)

MSAK:

MSAS_53370(cofC)

MKU:	I2456_08815(cofC)

MLW:	MJO58_08615(cofC)

MXE:	MYXE_33790(cofC)

MNV:	MNVI_31490(cofC)

MPAG:

C0J29_10100(cofC)

MNM:	MNVM_33640(cofC)

MGOR:

H0P51_09495(cofC)

MCOO:

MCOO_49500(cofC)

MBAI:

MB901379_01544(cofC)

MSEO:

MSEO_04010(cofC)

MHEK:

JMUB5695_03349(cofC)

MGAU:

MGALJ_05850(cofC)

MLJ:	MLAC_29160(cofC)

MBRD:

MBRA_48330(cofC)

MSHJ:

MSHI_06950(cofC)

MMAM:

K3U93_07645(cofC)

MSPG:

F6B93_07000(cofC)

MOT:	LTS72_16475(cofC)

MLM:	MLPF_0965(cofC)

MPAA:

MKK62_16420(cofC)

MMEH:

M5I08_05455(cofC)

MKY:	IWGMT90018_18720(cofC)

MADI:

A7U43_20335

MWU:	PT015_01545(cofC)

MSM:	MSMEG_2392

MSG:	MSMEI_2332

MSB:	LJ00_11895

MSN:	LI99_11895

MSH:	LI98_11900

MVA:

Mvan_2140

MGI:

Mflv_4222

MSP:	Mspyr1_35650

MCB:	Mycch_1858

MNE:	D174_10725

MYN:	MyAD_10515

MFT:	XA26_23710

MPHL:

MPHLCCUG_02064(cofC)

MVQ:

MYVA_2029

MLL:	B1R94_18650

MRH:	MycrhN_5891

MTHN:

4412656_01564(cofC)

MHAS:

MHAS_00955(cofC_1)

MDU:	MDUV_23860(cofC)

MCHT:

MCHIJ_45840(cofC)

MDR:	MDOR_13130(cofC)

MAUU:

NCTC10437_01993(cofC)

MMAG:

MMAD_21070(cofC)

MMOR:

MMOR_43460(cofC)

MFX:	MFAL_02200(cofC)

MAIC:

MAIC_18060(cofC)

MIJ:	MINS_20020(cofC)

MALV:

MALV_15640(cofC)

MTY:	MTOK_39600(cofC)

MPSC:

MPSYJ_45240(cofC)

MARZ:

MARA_19270(cofC)

MGAD:

MGAD_18180(cofC)

MHEV:

MHEL_42690(cofC)

MSAR:

MSAR_48590(cofC)

MANY:

MANY_04000(cofC)

MAUB:

MAUB_54100(cofC)

MPOF:

MPOR_24740(cofC)

MPHU:

MPHO_15090(cofC)

MMUC:

C1S78_010750(cofC)

MMAT:

MMAGJ_53750(cofC)

MBOK:

MBOE_51520(cofC)

MFG:	K6L26_20825(cofC)

MSEI:

MSEDJ_33470(cofC)

MFLV:

NCTC10271_03399(cofC)

MCEE:

MCEL_16310(cofC)

MBRM:

L2Z93_001100(cofC)

MMON:

EWR22_09780(cofC)

MGO:	AFA91_27570

MHOL:

K3U96_17180(cofC)

MSEN:

K3U95_18265(cofC)

MPAE:

K0O64_10120(cofC)

MRF:	MJO55_09655(cofC)

MDF:	K0O62_10745(cofC)

MCRO:

MI149_11010(cofC)

MGRO:

FZ046_15810(cofC)

MKR:	MKOR_17450(cofC)

MPAK:

MIU77_12700(cofC)

MAB:

MAB_3289

MMV:	MYCMA_1808

MABB:

MASS_3234

MABL:

MMASJCM_3296

MCHE:

BB28_16595

MIZ:	BAB75_17560

MSTE:

MSTE_03266(cofC)

MSAO:

MYCSP_14985

MSAL:

DSM43276_03084(cofC)

MJD:	JDM601_2686

MTER:

4434518_02632(cofC)

MMIN:

MMIN_03860(cofC)

MHIB:

MHIB_21180(cofC)

MHER:

K3U94_15365(cofC)

MVM:	MJO54_15315(cofC)

ASD:

AS9A_3180

NFA:

NFA_42070

NFR:	ERS450000_05708(cofC)

NCY:	NOCYR_3926

NBR:	O3I_031680

NNO:	NONO_c56690(cofC)

NSL:	BOX37_21875

NSR:	NS506_06550(cofC)

NTP:	CRH09_28310(cofC)

NOZ:	DMB37_10555(cofC)

NOD:	FOH10_21705(cofC)

NAH:	F5544_34235(cofC)

NAD:	NCTC11293_05426(cofC)

NWL:	NWFMUON74_20620(cofC)

NIE:	KV110_30585(cofC)

NTC:	KHQ06_34075(cofC)

NHU:	H0264_33010(cofC)

NYA:	LTV02_00985(cofC)

NGP:	LTT66_22920(cofC)

NSPU:

IFM12276_14390(cofC)

NYU:	D7D52_16265(cofC)

RHA:	RHA1_ro06504 RHA1_ro11040

RER:

RER_24130

REY:

O5Y_11330

REB:	XU06_11540

RQI:	C1M55_12595(cofC)

ROP:

ROP_65550

ROA:	Pd630_LPD03172

RPY:	Y013_06640

RBY:	CEJ39_17560(cofC)

RHB:

NY08_1486

RAV:	AAT18_16270

RFA:	A3L23_04716(cofC)

RHS:	A3Q41_03554(cofC)

RHW:	BFN03_05430

RRZ:	CS378_05860(cofC)

RHU:	A3Q40_01319(cofC)

RHQ:	IM25_20660

RHOD:

AOT96_22805

RRT:	4535765_03146(cofC)

RCR:	NCTC10994_04100(cofC)

RTM:	G4H71_18840(cofC)

RKO:	JWS14_25805(cofC) JWS14_35265(cofC)

RGO:	KYT97_00015(cofC)

ROZ:	CBI38_18260

RPSK:

JWS13_08660(cofC)

RGOR:

NMQ04_13500(cofC)

RHOP:

D8W71_14805(cofC)

REQ:

REQ_31310

PDEF:

P9209_13175

WHR:	OG579_05390(cofC)

GBR:

Gbro_3210

GPO:	GPOL_c29880(cofC)

GOR:

KTR9_3249

GOQ:	ACH46_14035

GTA:	BCM27_16535

GOC:	CXX93_08970(cofC)

GIT:	C6V83_14100(cofC)

GRU:	GCWB2_16720(cofC)

GOM:	D7316_00062(cofC)

GAV:	C5O27_11430(cofC)

GOD:	GKZ92_15650(cofC)

GAM:	GII34_15430(cofC)

GPD:	GII33_14595(cofC)

GJI:	H1R19_15585

GOI:	LK459_18355(cofC)

GHN:	MVF96_16010(cofC)

GAMI:

IHQ52_19520(cofC)

GSI:	P5P27_13280(cofC)

SPIN:

KV203_12370(cofC)

TPR:

Tpau_2843

TSM:	ASU32_15845

TPUL:

TPB0596_16360(cofC)

TSD:	MTP03_32760(cofC)

SRT:

Srot_0988

DTM:	BJL86_1921

DIT:	C3V38_15185(cofC)

DIZ:	CT688_09310(cofC)

DPC:	A6048_09530

DLU:	A6035_09060

TOY:	FO059_10860(cofC)

SCO:	SCO5557a(SC7A1.01c)

SALB:

XNR_1250

SMA:	SAVERM_2682

SGR:

SGR_1924

SGB:

WQO_25885

SFI:

SFUL_5452

SANL:

KZO11_27435(cofC)

SGRF:

SGFS_039800

SCYE:

R2B67_08375(cofC)

SCB:	SCAB_26561

SSX:	SACTE_4777

SVL:	Strvi_1908

SHY:

SHJG_6669

SHO:	SHJGH_6429

SRC:	M271_15965 M271_39000

SMAL:

SMALA_5521 SMALA_6222

SSOI:

I1A49_31285(cofC) I1A49_34950(cofC)

SFA:

Sfla_1744

SBH:

SBI_03506

SVE:

SVEN_5249

SDV:	BN159_2839(cofC)

SALS:

SLNWT_1680

STRP:

F750_5101

SCI:	B446_26095

SLV:	SLIV_10690(cofC)

SGU:	SGLAU_23935

SVT:	SVTN_26990

STRE:

GZL_03181

SCW:	TU94_23495

SLD:

T261_2488

SLC:	SL103_28060

SXI:	SXIM_43720

STRC:

AA958_25755

SAMB:

SAM23877_5311(cofC)

SPRI:

SPRI_2301

SCZ:	ABE83_09445

SCX:	AS200_15595

SRW:	TUE45_06075(cofC_2)

STRF:

ASR50_25210

SLE:	sle_20990(sle_20990)

SRN:	A4G23_04119(cofC)

SPAV:

Spa2297_23565

STRT:

A8713_22665

SCLF:

BB341_06370

SGS:	AVL59_08895

STSI:

A4E84_28475

SKY:	D0C37_07825(cofC)

SGM:	GCM10017557_23100(cofC)

SCAD:

DN051_12455(cofC)

SPHW:

NFX46_07715(cofC)

SLS:	SLINC_5998

SNR:	SNOUR_13820

SALU:

DC74_5687

SALL:

SAZ_30090

SPLU:

LK06_024120

STRD:

NI25_11405

SAUO:

BV401_31485 BV401_35040

SVU:	B1H20_26440

SPUN:

BFF78_13250

SGV:	B1H19_28460

SLAU:

SLA_5459

SALF:

SMD44_06197(cofC)

SALJ:

SMD11_2002(cofC)

SLX:	SLAV_11910(cofC2)

STRO:

STRMOE7_27305

SFK:

KY5_5735c

SNZ:	DC008_24980(cofC)

SGE:	DWG14_02500(cofC_2)

SRJ:

SRO_2266

SLK:	SLUN_28205(cofC)

SDX:	C4B68_11425(cofC)

SGD:	ELQ87_11795(cofC)

SQZ:	FQU76_24855(cofC)

SCYA:

EJ357_32820(cofC)

SAST:

CD934_09205(cofC)

SNQ:	CP978_23945(cofC)

STIR:

DDW44_22025(cofC)

SKA:	CP970_12385(cofC)

SGZ:	C0216_06565(cofC)

SVN:	CP980_09660(cofC)

SHAW:

CEB94_29110(cofC)

SRK:	FGW37_23495(cofC)

SFIC:

EIZ62_08595(cofC)

SSPO:

DDQ41_20755(cofC)

SPAD:

DVK44_25760(cofC)

SFY:	GFH48_04690(cofC) GFH48_13135(cofC)

SAQU:

EJC51_34045(cofC)

SGF:	HEP81_02476(cofC)

SCAV:

CVT27_25275(cofC)

SSEO:

D0Z67_20900(cofC)

SBY:	H7H31_08120(cofC)

SRIM:

CP984_11265(cofC)

SSUB:

CP968_09955(cofC)

SPHV:

F9278_35195(cofC)

SCIN:

CP977_24650(cofC)

SFUG:

CNQ36_28000(cofC)

SPAC:

B1H29_10785

STSU:

B7R87_24865

SGX:	H4W23_28470(cofC)

SCOE:

CP976_30725(cofC)

SBAT:

G4Z16_08105(cofC)

SNF:	JYK04_05960(cofC_3)

SPLA:

CP981_27670(cofC)

SBRO:

GQF42_30560(cofC)

STUI:

GCM10017668_50670(cofC)

SATA:

C5746_29650(cofC)

SCHF:

IPT68_26420(cofC)

SHUN:

DWB77_02325(cofC_2)

SHAR:

HUT13_21790(cofC)

SCYG:

S1361_27655(cofC)

SLIA:

HA039_09235(cofC)

SDW:	K7C20_26345(cofC)

SVD:	CP969_26865(cofC)

SCAL:

I6J39_26120(cofC)

SAUH:

SU9_025070(cofC)

SFB:	CP974_22240(cofC)

SMOB:

J7W19_23340(cofC)

SPRA:

CP972_25245(cofC)

SPEU:

CGZ69_25870(cofC)

SROI:

IAG44_11230(cofC)

SXN:	IAG42_09850(cofC)

SGJ:	IAG43_22990(cofC)

SHK:	J2N69_26640(cofC)

SANU:

K7396_10495(cofC)

STRY:

EQG64_26295(cofC)

SMAO:

CAG99_04955

SGOB:

test1122_20165(cofC)

SINE:

KI385_31570(cofC)

SLF:	JEQ17_14615(cofC) JEQ17_32790(cofC)

SDEC:

L3078_32305(cofC)

SAOV:

G3H79_09910(cofC)

SDUR:

M4V62_13595(cofC)

SYAN:

NRK68_24430(cofC)

SRUG:

F0345_21750(cofC)

SAKB:

K1J60_12925(cofC)

STAA:

LDH80_12440(cofC)

SNIG:

HEK616_54760(cofC)

SVIO:

HWN34_06930(cofC)

SCAE:

IHE65_12430(cofC)

STUB:

MMF93_24260(cofC)

SSPN:

LXH13_28205(cofC)

SCIR:

STRCI_005744(cofC)

SXT:	KPP03845_105300(cofC)

SLON:

LGI35_30525(cofC)

SDRZ:

NEH16_08670(cofC)

STUD:

STRTU_001977(cofC)

STEE:

F3L20_07035(cofC)

SENG:

OJ254_01510(cofC)

SANT:

QR300_34405(cofC)

SYUN:

MOV08_13660(cofC)

SARG:

HKX69_09810(cofC)

SJN:	RI060_11715(cofC)

SCYN:

N8I84_28135(cofC)

SOV:	QZH56_08700(cofC)

SFIY:

F0344_08980(cofC)

SHAU:

K9S39_14685(cofC)

SKG:	KJK29_09795(cofC)

SCOA:

QU709_11485(cofC)

SLAI:

P8A22_10615(cofC)

SFP:	QUY26_10565(cofC)

SCHG:

NRO40_21530(cofC)

STTN:

BSL84_23880

SINN:

ABB07_11235

STRZ:

OYE22_07905(cofC)

SCT:

SCAT_4391

SCY:	SCATT_43810

KSK:

KSE_51470

KAB:	B7C62_27190

KAU:	B6264_06285

KIT:	CFP65_5115

STRI:

C7M71_021410(cofC) C7M71_029930

YIA:	LO772_11440(cofC)

STRH:

GXP74_33115(cofC)

ABRY:

NYE86_27045(cofC)

AGLA:

OIE69_13805(cofC)

LXL:	KDY119_01329(cofC)

PSIC:

J4E96_05900(cofC)

MTS:

MTES_1877

MCW:	A8L33_02345

MIH:	BJP65_10330

MLV:	CVS47_03054(cofC)

MWA:	E4K62_17130(cofC)

MPRT:

ET475_03925(cofC)

MSED:

E3O41_12540

MSF:	IT882_14575(cofC)

MCAW:

F6J84_13725

MLZ:	F6J85_16150(cofC)

MBIN:

LXM64_14335

MTEC:

OAU46_00550(cofC)

MELY:

L2X98_28680(cofC)

MRG:	SM116_03175(cofC)

MINV:

T9R20_15335(cofC)

MOJ:	D7D94_11940(cofC)

RTX:	TI83_07560

RTC:	APU90_09520

RTN:	A6122_1638

RRY:	C1O28_07695(cofC)

RIA:	C7V51_06125(cofC)

RFS:	C1I64_03775(cofC)

RTE:	GSU10_09065(cofC)

ROE:	Q0F99_20365(cofC)

MVD:	AWU67_15855

FSB:	GCM10025867_09940(cofC)

AGY:	ATC03_18490

AGM:	DCE93_00265 DCE93_13675(cofC)

AGF:	ET445_04900(cofC)

AMAU:

DSM26151_28150(fbiD)

ASOI:

MTP13_06245(cofC)

AMAV:

GCM10025877_13550(cofC)

ALAV:

MTO99_13430

AIL:	FLP10_09970

CART:

PA27867_3313

CRY:	B7495_16090(cofC)

CPHY:

B5808_11975

CHRE:

IE160_09590(cofC)

MHUM:

NNL39_01315(cofC) NNL39_01410(cofC)

MDB:	OVN18_01225(cofC)

HUM:	DVJ78_08975(cofC)

GRY:	D7I44_06935(cofC)

LALL:

MUN78_02055

AGRO:

JSQ78_05230(cofC)

MANT:

BHD05_14675

HEA:	HL652_10845(cofC)

HEH:	L3i23_06170(cofC)

GLN:	F1C58_11310(cofC)

AGX:	AGREI_0998(fbiD)

SUBT:

KPL76_08055(cofC)

SUBA:

LQ955_10145(cofC)

HOM:	OF852_06370(cofC)

AOG:	LH407_11855(cofC)

AJR:	N2K98_15935(cofC)

DAY:	FV141_08960

DERM:

H7F30_08465

LMOI:

VV02_11535

YIM:	J5M86_04825(cofC)

ALX:	LVQ62_15835(cofC)

BEI:	GCM100_23730(cofC)

XCE:

Xcel_3010

XYL:	ET495_10990(cofC)

XYA:	ET471_03445(cofC)

IVA:	Isova_2672

IDO:	I598_2997(cofC)

CET:	B8281_07120

CCEU:

CBR64_04240

SKE:	Sked_24100

CFI:

Celf_1449

CGA:	Celgi_2152

CELZ:

E5225_11000(cofC)

CEJ:	GC089_11370(cofC)

CELH:

GXP71_04065(cofC)

CIRA:

LFM56_11090(cofC)

CELC:

K5O09_06685(cofC)

CFEN:

KG102_06205(cofC)

OEK:	FFI11_000585(cofC)

PSEK:

GCM125_00160(cofC_1) GCM125_32850(cofC_2)

ICA:	Intca_2327

ARS:	ADJ73_15150

JTE:	ASJ30_13415

TEH:	GKE56_08190(cofC)

PHW:	G7075_03370(cofC)

PEI:	H9L10_08235(cofC)

TED:	U5C87_19300(cofC)

SERJ:

SGUI_3236

SERW:

FY030_10045(cofC)

ORN:	DV701_00435(cofC)

ORZ:	FNH13_13235(cofC)

ORD:	L0A91_01760(cofC)

OCP:	NF557_11370(cofC)

AUS:	IPK37_01160(cofC)

GYU:	FE374_01135(cofC)

MPH:

MLP_20890

MIK:	FOE78_16060(cofC)

MICG:

GJV80_10020(cofC)

NCA:	Noca_0815 Noca_0865 Noca_3295

NDK:	I601_2494(cofC_1)

NOY:	EXE57_18415(cofC)

NOI:	FCL41_05390(cofC)

NOO:	FE634_14930(cofC)

NDP:	E2C04_06020(cofC)

NSN:	EXE58_01085 EXE58_11170

NBE:	Back2_26840(cofC)

NANO:

G5V58_05620(cofC)

NMES:

H9L09_16505(cofC)

NARO:

CFH99_17275(cofC) CFH99_24615

NPI:	G7071_17780(cofC)

NAQU:

ENKNEFLB_01346(cofC)

NRO:	K8W59_13710(cofC)

NOQ:	LN652_06045(cofC) LN652_12925

NCQ:	K6T13_11870(cofC)

NPC:	KUV85_02385(cofC)

NPS:	KRR39_04245(cofC)

NMAR:

HPC71_06950(cofC)

NFC:	KG111_05145(cofC)

PSIM:

KR76_18435

AEF:	GEV26_03335(cofC)

ASEZ:

H9L21_12190(cofC)

ADB:	NP095_12140(cofC)

AWN:	NQV15_14400(cofC)

SGRG:

L0C25_01095(cofC)

NBT:	KLP28_08785

KFL:

Kfla_4853

KQI:	F1D05_06570(cofC)

KSL:	OG809_40175(cofC)

TFU:

Tfu_0629

THAO:

NI17_000080(cofC)

TALX:

FOF52_21090(cofC)

NDA:

Ndas_0188

NAL:	B005_3031(cofC)

NGV:	CDO52_22350(cofC)

NEX:	NE857_07070(cofC)

NEC:	KGD82_22430(cofC)

NAKE:

KGD83_24885(cofC)

NCG:	KGD84_26585(cofC)

STRR:

EKD16_05935(cofC1)

SNAH:

OUQ99_26395(cofC)

SAIU:

J4H86_23140(cofC)

TCU:

Tcur_3458

ACTW:

F7P10_33665(cofC)

AGRA:

AGRA3207_006249(cofC)

ACIR:

OG979_07080(cofC)

SPIQ:

OHA34_32775(cofC)

ACTQ:

OG417_16635(cofC)

SRO:

Sros_8012

NOA:	BKM31_53690

NOW:	GBF35_42515(cofC)

NCX:	Nocox_34985(cofC2)

NGN:	LCN96_47635(cofC)

NFS:	OIE67_01325(cofC)

TBI:

Tbis_2795

MHAI:

OHB01_02680(cofC)

FRA:	Francci3_3616

FRE:	Franean1_1121

FAL:

FRAAL5823

FSY:	FsymDg_3702

FRI:	FraEuI1c_1043

ACE:

Acel_1961

NML:

Namu_3538

NAK:	EH165_05645

NAKA:

H7F38_13275(cofC)

GOB:

Gobs_4049

BSD:	BLASA_3830

BLAP:

MVA48_07510(cofC)

MMAR:

MODMU_4458(cofC)

KRA:

Krad_3631

SEN:

SACE_6139

SVI:	Svir_09110

SACC:

EYD13_04960(cofC)

AMD:

AMED_1729

AMN:

RAM_08780

AMM:

AMES_1716

AMZ:

B737_1717

AOI:

AORI_6141

AJA:	AJAP_08705

AMQ:	AMETH_1531

AMYC:

CU254_07045(cofC)

AMYB:

BKN51_24230

AAB:	A4R43_19565

AMYY:

YIM_10180(cofC2)

AORI:

SD37_30105

AACD:

LWP59_07750(cofC)

APRT:

MUY14_27810(cofC)

AROO:

NQK81_35960(cofC)

ATHM:

L1857_10310(cofC)

ARHD:

VSH64_46715(cofC)

PDX:

Psed_1837

PSEA:

WY02_10130

PAUT:

Pdca_53300(cofC)

PBRO:

HOP40_15245(cofC)

PPEL:

H6H00_14755(cofC)

APRE:

CNX65_29505(cofC)

AMI:

Amir_6000

SESP:

BN6_71830

SSYI:

EKG83_40185(cofC)

KAL:

KALB_7396

KUT:	JJ691_91990

KBU:	Q4V64_37570(cofC)

KPHY:

AOZ06_45225

AHM:	TL08_22625

ACTI:

UA75_26405

ACAD:

UA74_25820

AHG:	AHOG_23720(cofC)

ACTA:

C1701_06365(cofC)

ALO:

CRK58729

PMAD:

BAY61_06415

SACE:

GIY23_17570(cofC)

ACTU:

Actkin_04954(cofC)

CROS:

N8J89_34245(cofC)

ACTY:

OG774_11030(cofC)

UME:	RM788_17230(cofC)

STP:	Strop_1264

SAQ:

Sare_1155

MAU:	Micau_1335

MIL:

ML5_1581

MICB:

MicB006_1358

MTUA:

CSH63_17545(cofC)

MICH:

FJK98_07045(cofC)

MTEM:

GCE86_00800(cofC)

MCAB:

HXZ27_07905(cofC)

MSAG:

GCM10017556_39150(cofC)

MCRA:

ID554_05250(cofC) ID554_30055(cofC)

VER:	HUT12_07690(cofC) HUT12_14810(cofC)

MENO:

Jiend_14200(cofC)

MPRN:

Q3V37_00400(cofC)

ASE:

ACPL_7340

AMS:	AMIS_70890

ACTN:

L083_6929

AFS:

AFR_36660

ACTS:

ACWT_7210

AIH:	Aiant_31780(cofC)

ACTR:

Asp14428_61190(cofC)

ACTL:

L3i22_096640(cofC)

ASIC:

Q0Z83_099230(cofC)

AOU:	ACTOB_007621(cofC)

PLAB:

C6361_25210(cofC)

PLAT:

C6W10_13645(cofC)

PFLA:

Pflav_085520(cofC)

PSUU:

Psuf_048470(cofC)

ATL:	Athai_39060(cofC)

ASER:

Asera_35250(cofC)

PRY:	Prubr_39480

CATI:

CS0771_23100(cofC)

DVC:	Dvina_08115

DFU:	Dfulv_07530(cofC)

DROS:

Drose_07840(cofC)

DAUR:

Daura_07510(cofC)

NHY:	JQS43_18680(cofC)

CCAZ:

COUCH_07825(cofC)

CAI:

Caci_8045

AEY:	CDG81_06975(cofC)

EKE:	EK0264_16945(cofC)

JTL:	M6D93_08120(cofC)

JCY:	M6B22_03505(cofC)

ABAI:

IMCC26256_11692

RXY:

Rxyl_0959

RRD:	RradSPS_0869

RUB:	GBA63_07055(cofC)

BSOL:

FSW04_11715(cofC)

BALA:

DSM104299_01949(fbiD)

CWO:

Cwoe_4150

PARN:

NBH00_07365(cofC)

PBAJ:

LRS13_14370(cofC)

TALU:

JDY09_03400(cofC)

AFO:

Afer_0590

AYM:	YM304_14940

ATQ:	GH723_06255(cofC)

AQZ:	KSP35_08865(cofC)

IAM:	HC251_05860(cofC)

DHI:	LH044_05640(cofC)

RRS:	RoseRS_1139

RCA:

Rcas_3980

CAU:

Caur_0203

CHL:	Chy400_0217

CAG:

Cagg_0666

ATM:

ANT_14440

ABAT:

CFX1CAM_1028(cofC)

PSUB:

Pelsub_P1765

CAP:	CLDAP_12750

PBF:	CFX0092_A2814(cofC)

KBS:	EPA93_18915(cofC)

KBB:	ccbrp13_68180

TBH:	Tbon_06690(cofC)

TFLA:

O0235_07305(cofC)

THUG:

KNN16_12955(cofC)

TTR:

Tter_1863

PMET:

G4Y79_17595(cofC)

TRO:

trd_A0802

STI:

Sthe_2612

MICA:

P0L94_12420(cofC)

MJA:

MJ_0887

MFE:	Mefer_1466

MVU:	Metvu_0088

MFS:	MFS40622_1271

MIF:	Metin_1017

MJH:	JH146_1020

MESG:

MLAUSG7_1408(cofC)

MESA:

MLASG1_0836(cofC)

MIG:	Metig_1008

MMP:

MMP0117

MMQ:	MmarC5_1561

MMX:	MmarC6_0835

MMZ:	MmarC7_1116

MMD:

GYY_00595

MMAK:

MMKA1_01220

MMAO:

MMOS7_01480

MMAD:

MMJJ_09690(cofC)

MAE:

Maeo_0658

MVN:	Mevan_1122

MVO:

Mvol_1513

MOK:	Metok_0929

METF:

CFE53_00255(cofC)

MTH:

MTH_613

MMG:	MTBMA_c09930(cofC)

MWO:	MWSIV6_0981(cofC)

MTEE:

MTTB_06640

METC:

MTCT_0537

METE:

tca_00584(cofC)

METZ:

METMT2_0437

METK:

FVF72_08500(cofC)

MTHM:

FZP57_04685(cofC)

METJ:

FZP68_05125(cofC)

MST:

Msp_1006

METB:

AW729_10865

MEIS:

PXD04_02665(cofC)

MRU:	mru_0953(cofC)

MSI:

Msm_0288

MEB:	Abm4_1210(cofC)

MMIL:

sm9_0770(cofC)

MEYE:

TL18_06430

MOL:

YLM1_0512

MARO:

MarbSA_05020

METV:

K4897_01935(cofC)

MEL:	Metbo_1012

MEW:	MSWAN_1224

METH:

MBMB1_0899(cofC)

MFC:	BRM9_1067(cofC)

MFI:	DSM1535_1728(cofC)

MCUB:

MCBB_1179(cofC)

MSUB:

BK009_04130

METN:

BK008_11825

METT:

CIT01_09280(cofC)

METO:

CIT02_01080(cofC)

MEME:

HYG87_09655(cofC)

MFEG:

GCM10025860_23380

MFV:

Mfer_1039

MKA:

MK0587

AFU:

AF_2061

AFG:	AFULGI_00023290

APO:	Arcpr_0054

AVE:	Arcve_1619

AST:	Asulf_00245

FPL:

Ferp_1821

GAC:

GACE_2043

GAH:

GAH_00650

MBA:	Mbar_A3418

MBY:	MSBRM_1569

MBW:	MSBRW_1316

MBAR:

MSBR2_0840

MBAK:

MSBR3_1293

MAC:

MA_1488

MMA:

MM_2497

MMAZ:

MmTuc01_2547

MMJ:	MSMAS_2205

MMAC:

MSMAC_2249

MVC:	MSVAZ_1510

MEK:	MSKOL_1451

MLS:	MSLAZ_1443

METM:

MSMTP_0956

MEF:	MSWH1_1900

MEQ:	MSWHS_3171

MSJ:	MSSAC_1458

MSZ:	MSSIH_1497

MSW:	MSSIT_1555

MTHR:

MSTHT_0215

MTHE:

MSTHC_0516

MHOR:

MSHOH_2815

MFZ:	AOB57_001350(cofC)

MBU:

Mbur_1305

MMET:

MCMEM_1752

MELO:

J7W08_07790(cofC)

MMH:

Mmah_1611

MHAZ:

BHR79_05670

MPOT:

BKM01_01765

MEV:	Metev_0264

MZH:	Mzhil_1606

MPY:

Mpsy_2556

MZI:	HWN40_09680(cofC)

MMAV:

RE476_00460(cofC)

MSEB:

RE474_10195(cofC)

MHZ:	Metho_0949

MEHF:

MmiHf6_00870(fbiD)

MEES:

MmiEs2_09190(fbiD)

MTP:

Mthe_0159

MCJ:

MCON_0918

MHI:

Mhar_1185

MHU:

Mhun_1254

MRTJ:

KHC33_06680(cofC)

MLA:

Mlab_1358

MEM:	Memar_1837

MBG:	BN140_0552

MEMA:

MMAB1_0692(cofC)

MCHK:

MchiMG62_21400(cofC)

MSUM:

OH143_03435(cofC)

MRC:	R6Y96_08865(cofC)

MPI:

Mpet_0719

MEND:

L6E24_05015(cofC)

MEFW:

F1737_07475(cofC)

MAQE:

RJ40_09450(cofC)

MFK:	E2N92_09645(cofC)

MOU:	OU421_00050(cofC)

MESB:

L1S32_04775(cofC)

MANQ:

L1994_07970(cofC)

MBN:

Mboo_2198

MFO:	Metfor_0523

MPL:

Mpal_0429

MPD:

MCP_2460

MEZ:

Mtc_2397

RCI:

RCIX464

HAL:

VNG_1935C

HSL:	OE_3721F(cofC)

HANR:

LJ422_07790(cofC)

HDL:	HALDL1_14650

HHB:	Hhub_3261(cofC)

HAGS:

JT689_09120(cofC)

HABO:

JRZ79_07530(cofC)

HNO:	LT974_13095(cofC)

HLU:	LT972_01735(cofC)

HALH:

HTSR_1970

HHSR:

HSR6_2045

HSU:	HLASF_1949

HSF:	HLASA_1935

HAHS:

HSRCO_2580

SALR:

FQU85_06440(cofC)

HALR:

EFA46_002105(cofC)

HJE:	HacjB3_04940

HDO:	MUK72_01410(cofC)

HALX:

M0R89_03585(cofC)

HAXZ:

M0R88_03795(cofC)

HAYC:

NGM10_11345(cofC)

HAXY:

NGM07_09360(cofC)

SALI:

L593_00100

SAIM:

K0C01_04285(cofC)

HARA:

AArcS_2544

HMA:

rrnAC3282

HHI:

HAH_0521

HHN:	HISP_02700

HAB:	SG26_10490

HTA:	BVU17_02580

HALJ:

G9465_17515(cofC)

HSIN:

KDQ40_10900(cofC)

NPH:	NP_2400A(cofC)

NMO:	Nmlp_2440(cofC)

NHO:	HWV23_14450(cofC)

NSAL:

HWV07_16065(cofC)

HUT:

Huta_1302

HTI:

HTIA_1195

HALA:

Hrd1104_08995(cofC)

HASV:

SVXHr_0322(cofC)

HABN:

HBNXHr_0309(cofC)

HMU:

Hmuk_1414

HALZ:

E5139_10225(cofC)

HALL:

LC1Hm_0631(cofC)

HAZP:

GBQ70_10220(cofC)

HALI:

BV210_12055

HSN:	DV733_02240(cofC)

HDS:	HSR122_0586

HRR:	HZS55_07085(cofC)

HPEL:

HZS54_07645(cofC)

HLT:	I7X12_07095(cofC)

HARC:

HARCEL1_07495(cofC)

SSAI:

N0B31_11715(cofC)

HAAD:

MW046_01295

HWA:	HQ_3149A(cofC)

HWC:	Hqrw_3691(cofC)

HVO:	HVO_2202(cofC)

HME:

HFX_2259

HGI:	ABY42_11025

HALE:

G3A49_14450(cofC)

HLS:	KU306_02040(cofC)

HLN:	SVXHx_2366(cofc)

HBO:	Hbor_06400

HAQ:	DU484_16960(cofC)

HAJ:	DU500_00005(cofC)

HAER:

DU502_15175(cofC)

HRA:	EI982_15465(cofC)

HLM:	DV707_03520(cofC)

HALM:

FCF25_02490(cofC)

HLA:

Hlac_1893

HALP:

DOS48_09140(cofC)

HALB:

EKH57_01595(cofC)

HEZZ:

EO776_09580(cofC)

HALQ:

Hrr1229_010320(cofC)

HSS:	J7656_06495(cofC)

HSAI:

HPS36_12020(cofC)

HAZZ:

KI388_08025(cofC)

SRUB:

C2R22_17235(cofC)

HAE:	halTADL_3055

HALN:

B4589_007605(cofC)

HALG:

HUG10_08930(cofC)

HALU:

HUG12_07215(cofC)

HMP:	K6T50_06465(cofC)

HRE:	K6T36_06235

HRM:	K6T25_09555

HACB:

Hbl1158_13125(cofC)

HDF:	AArcSl_2530(cofC)

HAH:	Halar_2225

HTU:

Htur_0640

HSAL:

JMJ58_05915(cofC)

HAKZ:

J0X25_10520(cofC) J0X25_19340(cofC)

NMG:	Nmag_2631(cofC)

HXA:	Halxa_1898

NAT:

NJ7G_3939

NPE:	Natpe_3127

NVR:	FEJ81_14710(cofC)

NPL:	FGF80_13920(cofC)

NAY:	HYG81_17925(cofC)

HALY:

HYG82_19870(cofC)

HJT:	DVR14_05760(cofC)

HLO:	J0X27_17395(cofC)

NGE:	Natgr_1126

HRU:	Halru_0971

SAWL:

NGM29_15925(cofC)

HALV:

NGM15_07100(cofC)

NOU:	Natoc_0462

HLR:	HALLA_06790

HLC:	CHINAEXTREME01800

NAJ:	B1756_17595

NAG:	AArcMg_3218

NAN:	AArc1_3127

NARA:

QQ977_04760(cofC)

NBG:	DV706_04175(cofC)

NAS:	GCU68_09395(cofC)

HDA:	BB347_10785

MELU:

MTLP_05320(cofC)

MEAM:

MU439_00975(cofC)

MEAE:

QEN48_01630

NMR:

Nmar_0625

NIR:	NSED_03220

NKR:	NKOR_03200

NID:	NPIRD3C_1642

NIN:	NADRNF5_1525

NIW:	Nisw_01785(cofC)

NCL:	C5F47_05950(cofC)

NOX:	C5F49_05790(cofC)

NUE:	C5F50_04630(cofC)

NIP:	NsoK4_05240(cofC)

NZT:	NZOSNM25_001370

NCT:	NMSP_1059(cofC)

NIC:	DSQ20_03320(cofC)

NGA:	Ngar_c13860(cofC)

NVN:	NVIE_001520(cofC)

NEV:

NTE_01464

TAA:	NMY3_01424(cofC)

NFN:	NFRAN_2319(cofC)

NCV:	NCAV_1165(cofC)

CSY:	CENSYa_1216

CSU:	CSUB_C1238

NBV:	T478_0980(cofC)

TAH:	SU86_003070

NIU:	DSQ19_03540(cofC)

NCK:	QVH35_07585(cofC)

NDV:

NDEV_0696

LOKI:

Lokiarch_12870(cofC)

» show all

Reference

1 [PMID:18260642]

Authors

Grochowski LL, Xu H, White RH

Title

Identification and characterization of the 2-phospho-L-lactate guanylyltransferase involved in coenzyme F420 biosynthesis.

Journal

Biochemistry 47:3033-7 (2008)
DOI:10.1021/bi702475t

Sequence

[mja:MJ_0887]

Reference

2 [PMID:31469543]

Authors

Braga D, Last D, Hasan M, Guo H, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G

Title

Metabolic Pathway Rerouting in Paraburkholderia rhizoxinica Evolved Long-Overlooked Derivatives of Coenzyme F420.

Journal

ACS Chem Biol 14:2088-2094 (2019)
DOI:10.1021/acschembio.9b00605

Sequence

[brh:RBRH_02550]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.7.68

IUBMB Enzyme Nomenclature:

2.7.7.68

ExPASy - ENZYME nomenclature database:

2.7.7.68

BRENDA, the Enzyme Database:

2.7.7.68

DBGET integrated database retrieval system