KEGG   ENZYME: 2.7.8.40
Entry
EC 2.7.8.40                 Enzyme                                 
Name
UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase;
WecP;
UDP-GalNAc:polyprenol-P GalNAc-1-P transferase;
UDP-GalNAc:undecaprenyl-phosphate GalNAc-1-phosphate transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
UDP-N-acetyl-alpha-D-galactosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-galactosaminephosphotransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R10465]
Reaction(KEGG)
R10465
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
ditrans,octacis-undecaprenyl phosphate [CPD:C17556]
Product
UMP [CPD:C00105];
N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C20620]
Comment
The enzyme catalyses a step in the assembly of the repeating-unit of the O-antigen of the Gram-negative bacterium Aeromonas hydrophila AH-3. The enzyme shows no activity with UDP-N-acetyl-alpha-D-glucosamine (cf. EC 2.7.8.33, UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase).
History
EC 2.7.8.40 created 2013
Orthology
K21303  UDP-GalNAc:undecaprenyl-phosphate GalNAc-1-phosphate transferase
Genes
CAMH: LCW13_11555
COBE: CLAM6_23300(wcaJ_3)
COBB: H2O77_11870
ALCA: ASALC70_00659(wecA)
AHD: AI20_04960
ACAV: VI35_13815
AEA: C2U39_14420
ASIM: FE240_10020
AEJ: E5E97_19750
WCN: PE074_03445
POLL: OEG81_01130
AALN: Q3V95_02670
AAMM: FE795_15310
SZO: K8M09_15600
GLT: GlitD10_1687
GCY: LQF76_07380
DRD: LMT64_12450
 » show all
Reference
1  [PMID:21335454]
  Authors
Merino S, Jimenez N, Molero R, Bouamama L, Regue M, Tomas JM
  Title
A UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family.
  Journal
J Bacteriol 193:1943-52 (2011)
DOI:10.1128/JB.01441-10
  Sequence
[ag:ABX39510]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.40
IUBMB Enzyme Nomenclature: 2.7.8.40
ExPASy - ENZYME nomenclature database: 2.7.8.40
BRENDA, the Enzyme Database: 2.7.8.40

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Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (156)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (18)   
   RefGene (137)   
Protein sequence (521)   
   UniProt (519)   
   SWISS-PROT (2)   
DNA sequence (764)   
   GenBank (404)   
   EMBL (360)   
Protein domain (2)   
   InterPro (2)   
All databases (1449)   

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