KEGG ENZYME: 2.7.8.44

ENZYME: 2.7.8.44

Entry

EC 2.7.8.44                 Enzyme

Name

teichoic acid glycerol-phosphate primase;
Tag primase;
CDP-glycerol:glycerophosphate glycerophosphotransferase;
tagB (gene name);
tarB (gene name)

Class

Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups

Sysname

CDP-glycerol:N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol glycerophosphotransferase

Reaction(IUBMB)

CDP-glycerol + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = CDP + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R11558 R12860]

Reaction(KEGG)

R11558 R12860(G)

Substrate

CDP-glycerol [CPD:C00513];
N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C04881]

Product

CDP [CPD:C00112];
4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C21464]

Comment

Involved in the biosynthesis of teichoic acid linkage units in bacterial cell walls. This enzyme adds the first glycerol unit to the disaccharide linker of the teichoic acid.

History

EC 2.7.8.44 created 2016

Pathway

ec00552

Teichoic acid biosynthesis

Orthology

K21285

teichoic acid glycerol-phosphate primase

Genes

SLO:

Shew_3696

SJA:	SJ2017_0061

SMAV:

CFF01_18305

THT:	E2K93_04605

PDV:	FFU37_13135

TCY:	Thicy_0930

KGE:

TQ33_2188

SDO:	SD1155_05970

CFT:	CFF04554_1615

CFV:	CFVI03293_1637

CFX:	CFV97608_1740

CFZ:

CSG_17470

BSU:	BSU35760(tagB)

BSR:

I33_3705

BSL:

A7A1_1144

BSH:	BSU6051_35760(tagB)

BSY:	I653_17440

BSUT:

BSUB_03809(tagB)

BSUL:

BSUA_03809(tagB)

BSUS:

Q433_19590

BSO:	BSNT_10220(tagB)

BSN:	BSn5_08795

BSQ:	B657_35760(tagB)

BSX:	C663_3467(tarB)

BSP:	U712_17950

BSS:	BSUW23_17560(tarB)

BST:	GYO_3932(tarB)

BIT:	BIS30_07530

BLI:	BL02433(tagB)

BLD:	BLi03820(tagB)

BLH:	BaLi_c38320(tagB)

BAY:	RBAM_032890

BAQ:	BACAU_3319(tagB)

BYA:	BANAU_3478(tagB)

BAMP:

B938_16890

BQY:	MUS_3917(tagB)

BAML:

BAM5036_3213(tagB)

BAMA:

RBAU_3429(tagB)

BAMN:

BASU_3207(tagB)

BAMB:

BAPNAU_3486(tagB)

BAMT:

AJ82_18570

BAMY:

V529_35570(tagB)

BMP:	NG74_03465(tagB)

BAO:	BAMF_3415(tagB)

BAZ:	BAMTA208_18095(tagB)

BQL:	LL3_03710(tagB)

BXH:	BAXH7_03699(tagB)

BAMI:

KSO_002625

BAMC:

U471_34160

BAMF:

U722_17635

BSIA:

CWD84_02610

BAE:	BATR1942_15770

BVM:	B9C48_16875

BSON:

S101395_00593(tarL)

BHT:	DIC78_13190

BMOJ:

HC660_34660

BTEQ:

G4P54_18365

BIQ:	AN935_18020

BSTR:

QI003_21325(tagB)

BMYO:

BG05_726

BMYC:

DJ92_2373

BPU:

BPUM_3232

BPUM:

BW16_17250

BPUS:

UP12_16740

BGY:

BGLY_4217

BXI:	BK049_10710

BALT:

CFN77_17160

BAER:

BAE_05090

BSAF:

BSL056_17875

BFD:	NCTC4823_03769(tagF_4)

BSHI:

LGQ02_18320

BCAB:

EFK13_18405

BRY:	M0696_18125

BJS:

MY9_3629

BACW:

QR42_16245

BACP:

SB24_12250

BACB:

OY17_00125

BACY:

QF06_16285

BACL:

BS34A_38890(tagB)

BALM:

BsLM_3592

BACS:

AUL54_13150

BZH:	NF868_15065

BHAI:

KJK41_20500

BARD:

QRY57_25920

BAEI:

RE735_02990

BCIR:

C2I06_14140

NTX:	NQZ71_04650

BGI:	BGM20_12040

BKO:	CKF48_13440

GEA:	GARCT_03218(tagB)

AXL:	AXY_20290(tagB)

HNZ:	P9989_15745

HSHI:

MUO14_05590

HAMY:

MUO15_19015

TAID:

KS242_14100

VIR:	X953_16995 X953_17010

VHL:	BME96_16485 BME96_16495

VIG:	BKP57_07935

VIL:	CFK37_08170

VNE:	CFK40_03410

VPN:	A21D_00863(tagB)

VIM:	GWK91_11405

VPT:	KBP50_19475

FEC:	QNH15_21910

ACOP:

RI196_02660

BSJ:	UP17_23880

BMUR:

ABE28_022565

PBUT:

DTO10_10375

PASA:

BAOM_4717

PPSR:

I6J18_15985

PFRI:

L8956_17900 L8956_25340

PRD:	F7984_17495

NMK:	CHR53_23540

NCM:	QNK12_26945

NNV:	QNH39_26600

BLEN:

NCTC4824_03836(tagF_4)

SEDD:

ERJ70_16910

RMF:	D5E69_20535

RAZ:	U9J35_21345

BCK:	BCO26_0718

BAG:

Bcoa_0457

BCOA:

BF29_3239 BF29_3251

BVJ:	I5776_05250

BOU:	I5818_06580

FHL:	OE105_11210

FAF:	OE104_14470

SFOR:

QNH23_14165

ALKG:

MOJ78_18130

DOM:	RRU94_07440

STEA:

C0679_05935

PUK:	PU629_01905

SAU:	SA0595(tagB)

SAV:	SAV0639(tagB)

SAW:	SAHV_0636(tagB)

SAH:	SaurJH1_0677

SAJ:	SaurJH9_0662

SAM:	MW0601(tagB)

SAS:

SAS0605

SAR:	SAR0649(tagB)

SAC:	SACOL0696(tagB)

SAX:	USA300HOU_0659(tagB3)

SAA:	SAUSA300_0626(tagB)

SAO:	SAOUHSC_00643

SAE:	NWMN_0609(tagB)

SAD:	SAAV_0602(tagB)

SUU:	M013TW_0627

SUV:	SAVC_02830

SUE:

SAOV_0674

SUJ:	SAA6159_00594

SUK:	SAA6008_00656(tagB)

SUC:

ECTR2_591

SUT:	SAT0131_00708

SUQ:	HMPREF0772_12548

SUZ:

MS7_0690

SUD:	ST398NM01_0718

SUX:	SAEMRSA15_05650(tagB)

SUW:	SATW20_07140(tagB)

SUG:

SAPIG0718

SUF:	SARLGA251_05730(tagB)

SAUA:

SAAG_01062

SAUE:

RSAU_000595(tagB)

SAUN:

SAKOR_00633

SAUS:

SA40_0580(tagB)

SAUU:

SA957_0595(tagB)

SAUG:

SA268_0593(tagB)

SAUZ:

SAZ172_0651(tagB)

SAUT:

SAI1T1_2004930

SAUJ:

SAI2T2_1004950

SAUK:

SAI3T3_1004940

SAUQ:

SAI4T8_1004930

SAUV:

SAI7S6_1004940

SAUW:

SAI5S5_1004900

SAUX:

SAI6T6_1004910

SAUY:

SAI8T7_1004940

SAUF:

X998_0687

SAB:	SAB0589(tagB)

SUY:	SA2981_0615(tagB)

SAUB:

C248_0721(tagB)

SAUM:

BN843_6410

SAUC:

CA347_653

SAUR:

SABB_06074

SAUI:

AZ30_03350

SAUD:

CH52_02565

SAMS:

NI36_03200

SUH:	SAMSHR1132_05850

SER:

SERP0298

SEP:

SE_0413

SEPP:

SEB_00334

SEPS:

DP17_1717

SHA:	SH2257(tagB)

SHH:	ShL2_02107(tagB)

SSP:

SSP2080

SCA:	SCA_0288(tagB)

SLG:	SLGD_02185

SLN:	SLUG_21590(tagB)

SSD:	SPSINT_0348

SDT:	SPSE_2110(tagB)

SDP:	NCTC12225_02327(tagB)

SWA:	A284_10130

SPAS:

STP1_1725

SXY:	BE24_00955

SXL:	SXYLSMQ121_2057

SXO:	SXYL_02210(tagB)

SHU:	SHYC_10505(tagB)

SCAP:

AYP1020_0008(tagB)

SSCH:

LH95_10100

SSCZ:

RN70_10835

SAGQ:

EP23_11665

SEQO:

SE1039_04680

SSIF:

AL483_08410

SCV:	A4G25_06235

SPET:

CEP67_10185

SLZ:	B5P37_07655

SCOH:

BZ166_02355

SNL:	BJD96_11675

SKL:	C7J89_12250

SFQ:	C7J90_01525

SHOM:

EGX58_03025

SMUS:

C7J88_08660

SCAR:

DWB96_11030

SARL:

SAP2_21290

SPIC:

SAMEA4384060_2231(tagB)

SSH:	NCTC13712_00601

SSIM:

SAMEA4384339_0582(tagF_5)

SDB:	CNQ82_12560

SLLO:

ISP08_10515

SAUL:

I6G39_09520

SSAC:

I6I31_05980

SRAI:

LN051_09770

SPSD:

JMB28_11195

STAS:

HYI43_10470

SURY:

MUA21_01860

SEDA:

MNY58_11220

SCAQ:

QMO72_11105(tarB)

SDEV:

Q2T90_08475(tarB)

SROT:

ML435_02995

STAP:

AOB58_1289

SSCU:

CEP64_08370

SFF:	FOB90_09365

SSTE:

SAMEA4384403_1805(tagB)

MLEN:

H3V22_13600

MVT:	I6J10_02330

MARY:

LAU42_03810

MCL:

MCCL_0653

SHV:	AAT16_03995

JEA:	JEM45_04385

NAMP:

KPF49_02125

NMY:	CJ229_008655

LMO:	lmo1088(tagB)

LMN:	LM5578_1171(tagB)

LMY:	LM5923_1125(tagB)

LMT:	LMRG_00550

LMOC:

LMOSLCC5850_1094(tagB)

LMOE:

BN418_1306

LMOB:

BN419_1303

LMOD:

LMON_1098(tagB)

LMOW:

AX10_14020

LMOQ:

LM6179_01408

LMR:	LMR479A_1116

LMOM:

IJ09_04845

LMF:	LMOf2365_1104

LMC:	Lm4b_01103

LMOG:

BN389_11170(tagB)

LMP:

MUO_05690

LMOL:

LMOL312_1084(tagB)

LMOJ:

LM220_18775

LMOZ:

LM1816_14237

LMOX:

AX24_02840

LMH:	LMHCC_1543

LMQ:	LMM7_1114(tagB)

LML:	lmo4a_1092(tagB)

LMG:	LMKG_01832

LMS:

LMLG_2571

LMJ:	LMOG_00630

LMW:	LMOSLCC2755_1086(tagB)

LMX:	LMOSLCC2372_1102(tagB)

LMZ:	LMOSLCC2482_1132(tagB)

LMON:

LMOSLCC2376_1055(tagB)

LMOS:

LMOSLCC7179_1069(tagB)

LMOO:

LMOSLCC2378_1101(tagB)

LMOY:

LMOSLCC2479_1102(tagB)

LMOT:

LMOSLCC2540_1085(tagB)

LMOA:

LMOATCC19117_1106(tagB)

LMOK:

CQ02_05650

LMV:	Y193_10315

LIN:

lin1075

LWE:	lwe1065(tagB)

LSG:	lse_0978(tagB)

LIV:

LIV_1031

LII:	JL52_05480

LIW:	AX25_05570

LIA:	JL58_05700

LIO:	JL53_06190

LWI:	UE46_11725

LGZ:	NCTC10812_01809(tagF_5)

LMAR:

LAX80_005015

LNW:	OTR81_10245

BTHS:

CNY62_01040

ESI:

Exig_0594

EAN:

Eab7_0568

EXM:	U719_03105

EXU:	ESP131_05545

EACE:

KKI46_03305

PLN:	Plano_2228

PLL:	I858_011695

PDG:	BCM40_04110

PHC:	BBI08_08395

PGQ:	FK545_02145

KUR:	ASO14_2495

KZO:	NCTC404_00414(tagF_2)

SPAE:

E2C16_11345

RST:	ATY39_17045

PANC:

E2636_12050

PLAY:

DNR44_008290

VIJ:	JNUCC6_17780

LDE:	LDBND_0395(tarB)

LPX:	ASU28_08650

LPG:	BB562_07725

LSN:

LSA_07850

LLE:	AYR59_05205

LFV:	LF543_03650

LBH:

Lbuc_1007

LBN:	LBUCD034_1141(tagB)

LPAR:

FAM21731_02458

LCU:	PL11_009435

LKF:	DNL43_09525

LHIL:

G8J22_01371(tagB)

LBR:

LVIS_0739

LBK:	LVISKB_1240

LKO:	ABN16_12145

LZY:	LZ3411_1119

LSUA:

H3M12_08800

LJI:	ELX58_02170

LAGL:

BEN83_04750

LACA:

LAC1533_1167

LKU:	APS55_06025

ABOM:

D7I45_03070

LPD:	AYR62_05195

LMAE:

FGL90_09010

PPE:

PEPE_1113

PPEN:

T256_05475

PCE:

PECL_957

PDM:	ADU72_2183

PACI:

A4V11_02385

PIO:	PI20285_04425

ECAS:

ECBG_01909

ETH:	CK496_09740

ESG:	EsVE80_09540(tagB3)

EIE:	ENLAB_28960(tagB)

EDS:	PML78_02850

EMS:	P3T75_08440

THL:	TEH_16240(tagB) TEH_16360(tagB)

TEY:	GLW17_02030

TOO:	C7K38_10615

TKR:	C7K43_04375

VTE:	BHY08_07885

VPI:	BW732_01940

VAC:	E4Z98_08055

VAO:	FA707_08745

VAH:	G7081_00365

VCP:	H9L18_03815

VHY:	G7082_02265

VLC:	G314FT_20780(tagB)

CHY:

CHY_2587

TBM:	BK010_09645

PCU:	PC_RS08980

PNL:

PNK_2242

PUV:

PUV_00330

SNG:	SNE_A00890

RPOR:

RHAB15C_0000041

CPO:	COPRO5265_1091

TPRF:

A3L09_01825

» show all

Reference

1 [PMID:16150696]

Authors

Bhavsar AP, Truant R, Brown ED

Title

The TagB protein in Bacillus subtilis 168 is an intracellular peripheral membrane protein that can incorporate glycerol phosphate onto a membrane-bound acceptor in vitro.

Journal

J Biol Chem 280:36691-700 (2005)
DOI:10.1074/jbc.M507154200

Reference

2 [PMID:17163636]

Authors

Ginsberg C, Zhang YH, Yuan Y, Walker S

Title

In vitro reconstitution of two essential steps in wall teichoic acid biosynthesis.

Journal

ACS Chem Biol 1:25-8 (2006)
DOI:10.1021/cb0500041

Reference

3 [PMID:18215769]