| Entry |
|
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| Name |
steroid sulfotransferase;
steroid alcohol sulfotransferase;
3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase
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| Class |
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
|
|---|
| Sysname |
3'-phosphoadenylyl-sulfate:phenolic-steroid sulfonotransferase
|
|---|
| Reaction(IUBMB) |
3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate [RN: R03946]
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|---|
| Reaction(KEGG) |
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| Substrate |
3'-phosphoadenylyl sulfate [CPD: C00053];
phenolic steroid [CPD: C02453]
|
|---|
| Product |
adenosine 3',5'-bisphosphate [CPD: C00054];
steroid O-sulfate [CPD: C02590]
|
|---|
| Comment |
Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone.
|
|---|
| History |
EC 2.8.2.15 created 1984
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|---|
| Pathway |
| ec00140 | Steroid hormone biosynthesis |
|
|---|
| Reference |
|
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| Authors |
Adams JB, McDonald D. |
|---|
| Title |
Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals. |
|---|
| Journal |
|
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.8.2.15 |
| ExPASy - ENZYME nomenclature database: | 2.8.2.15 |
|
|---|
