KEGG   ENZYME: 2.8.2.24
Entry
EC 2.8.2.24                 Enzyme                                 
Name
aromatic desulfoglucosinolate sulfotransferase;
desulfoglucosinolate sulfotransferase (ambiguous);
PAPS-desulfoglucosinolate sulfotransferase (ambiguous);
3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase (ambiguous);
3'-phosphoadenylyl-sulfate:aromatic desulfoglucosinolate sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
Sysname
3'-phosphoadenylyl-sulfate:aromatic desulfoglucosinolate sulfonotransferase
Reaction(IUBMB)
(1) 3'-phosphoadenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-bisphosphate + glucotropeolin [RN:R03214];
(2) 3'-phosphoadenylyl sulfate + indolylmethyl-desulfoglucosinolate = adenosine 3',5'-bisphosphate + glucobrassicin [RN:R08167]
Reaction(KEGG)
R03214 R08167
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
desulfoglucotropeolin [CPD:C01069];
indolylmethyl-desulfoglucosinolate [CPD:C16517]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
glucotropeolin [CPD:C02153];
glucobrassicin [CPD:C05837]
Comment
This enzyme, characterized from cruciferous plants, catalyses the last step in the biosynthesis of tryptophan- and phenylalanine-derived glucosinolates. cf. EC 2.8.2.38, aliphatic desulfoglucosinolate sulfotransferase.
History
EC 2.8.2.24 created 1992, modified 2017
Pathway
ec00380  Tryptophan metabolism
ec00966  Glucosinolate biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K11821  aromatic desulfoglucosinolate sulfotransferase
Genes
ATHAT1G74100(SOT16)
ALY9323591
CRB17894300
CSAT104704865 104713044
EUSEUTSA_v10018795mg
BRP103831884 103852881
BNA106354366 106381367 106415773 111199316
BOE106296616 106327830
RSZ108814527 108820205
Reference
1  [PMID:2524977]
  Authors
Jain JC, Reed DW, GrootWassink JW, Underhill EW.
  Title
A radioassay of enzymes catalyzing the glucosylation and sulfation steps of glucosinolate biosynthesis in Brassica species.
  Journal
Anal Biochem 178:137-40 (1989)
DOI:10.1016/0003-2697(89)90369-2
Reference
2  [PMID:16367753]
  Authors
Klein M, Reichelt M, Gershenzon J, Papenbrock J
  Title
The three desulfoglucosinolate sulfotransferase proteins in Arabidopsis have different substrate specificities and are differentially expressed.
  Journal
FEBS J 273:122-36 (2006)
DOI:10.1111/j.1742-4658.2005.05048.x
  Sequence
[ath:AT1G74100]
Reference
3  [PMID:19077143]
  Authors
Klein M, Papenbrock J
  Title
Kinetics and substrate specificities of desulfo-glucosinolate sulfotransferases in Arabidopsis thaliana.
  Journal
Physiol Plant 135:140-9 (2009)
DOI:10.1111/j.1399-3054.2008.01182.x
  Sequence
[ath:AT1G74100]
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.24
IUBMB Enzyme Nomenclature: 2.8.2.24
ExPASy - ENZYME nomenclature database: 2.8.2.24
BRENDA, the Enzyme Database: 2.8.2.24
CAS: 121479-85-4

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