KEGG ENZYME: 2.8.2.37

ENZYME: 2.8.2.37

Entry

EC 2.8.2.37                 Enzyme

Name

trehalose 2-sulfotransferase;
Stf0 sulfotransferase;
3'-phosphoadenylyl-sulfate:alpha,alpha-trehalose 2-sulfotransferase

Class

Transferases;
Transferring sulfur-containing groups;
Sulfotransferases

Sysname

3'-phosphoadenylyl-sulfate:alpha,alpha-trehalose 2-sulfonotransferase

Reaction(IUBMB)

3'-phosphoadenylyl sulfate + alpha,alpha-trehalose = adenosine 3',5'-bisphosphate + 2-O-sulfo-alpha,alpha-trehalose [RN:R10971]

Reaction(KEGG)

R10971

Substrate

3'-phosphoadenylyl sulfate [CPD:C00053];
alpha,alpha-trehalose [CPD:C01083]

Product

adenosine 3',5'-bisphosphate [CPD:C00054];
2-O-sulfo-alpha,alpha-trehalose [CPD:C20985]

Comment

The sulfation of trehalose in the bacterium Mycobacterium tuberculosis is required for the biosynthesis of sulfolipid-1.

History

EC 2.8.2.37 created 2014

Orthology

K21014

trehalose 2-sulfotransferase

Genes

LEZ:

GLE_2492

LEM:

LEN_2518

LYA:	RDV84_19890

PSA:

PST_1401

SBL:

Sbal_1699

SBS:	Sbal117_1812

SBB:	Sbal175_2640

PAGA:

PAGA_a2042

PCAR:

PC2016_1536

AMG:	AMEC673_07475

ALR:	DS731_04820

ALE:	AV939_17530

ALZ:	AV940_17230

APEL:

CA267_005060

SALM:

D0Y50_03620

SALK:

FBQ74_13645

MPSY:

CEK71_13120 CEK71_14265

HSV:	HNO53_12130

HCAM:

I4484_09085

HSX:	HNO51_08795

REV:	HUE57_01120 HUE57_01125

BCED:

DM42_947

BTEI:

WS51_14685

BFN:

OI25_820

IDC:	LRM40_02130

JAL:	BZG29_04290

JRI:	P9875_04355

NIT:	NAL212_0593

NUR:	ATY38_02950

MBAC:

BN1209_1170

MLO:

mll3788

MLN:	A9174_06825

MCI:	Mesci_1366 Mesci_1869

MCIC:

A4R28_19845

MOP:	Mesop_1388 Mesop_6620

MAM:	Mesau_01404

MAMO:

A6B35_00680

MESW:

A9K65_007020 A9K65_009765

MESP:

C1M53_24955

MHUA:

MCHK_5143

MJR:	EB229_07015

MERD:

EB233_06935 EB233_24795 EB233_31880

PHT:	BLM14_22300

PHYL:

HB779_12160

RBS:	RHODOSMS8_00998(stf0)

SME:

SMc01744

SMK:	Sinme_2280

SMQ:	SinmeB_2124

SMX:	SM11_chr0957

SMI:	BN406_02129

SMEG:

C770_GR4Chr2358

SMEL:

SM2011_c01744

SMER:

DU99_12855

EGI:	PZN02_002969

SKM:	PZL22_002632

AVV:	RvVAT039_06310

AVF:	RvVAR031_26260

ALEG:

CFBP4996_25415

AVI:

Avi_3258

KAI:

K32_31720

MNO:

Mnod_7038

DEQ:	XM25_13065

YTI:	FNA67_16790

MMED:

Mame_00018

NOH:	G5V57_22275

LAP:	ACP90_01825 ACP90_23520

LABR:

CHH27_20440

LABP:

FJ695_23935

LABT:

FIU93_01275 FIU93_07450

LAGG:

B0E33_06980 B0E33_13340

SIW:	GH266_21045

SIL:

SPO3420

JAN:

Jann_2787

RED:	roselon_00619

YPAC:

CEW88_23565

SUAM:

BOO69_08760

SULZ:

C1J03_19535

SMED:

JNX03_04910

SUAL:

KDD17_13950

TOM:	BWR18_16245 BWR18_21205

RID:	RIdsm_04035 RIdsm_04606

THAA:

CFI11_06985

PAMI:

JCM7686_1672 JCM7686_pAMI4p230

PCON:

B0A89_05610

PARU:

CYR75_12500 CYR75_12505

PARS:

DRW48_09740

PMAU:

CP157_03559

RSU:

NHU_03816

TSCO:

R1T40_09500 R1T40_20960

DAA:	AKL17_2081

RBG:	BG454_18145

PPSO:

QPJ95_00190

BOO:	E2K80_01535

LIT:	FPZ52_07065 FPZ52_16980 FPZ52_18290

PPRU:

FDP22_03420 FDP22_10620 FDP22_23270

PAMO:

BAR1_07600

POZ:	I0K15_05295

FAP:	GR316_08645

NSM:	JO391_11565

RHOC:

QTA57_15220

MMR:	Mmar10_2509

SPAP:

H3Z74_01835

PMEA:

KTC28_22390

AFLV:

QQW98_01320

SHUM:

STHU_13100 STHU_17430 STHU_20770

STEL:

STAQ_10650 STAQ_18640 STAQ_36380 STAQ_36490

RRU:

Rru_A1625

RRF:

F11_08385

DEX:	HWD60_10125

NACI:

NUH88_09555

GSO:	PH603_05055

GEB:

GM18_0971

GSUB:

KP001_21515

GPL:	M1B72_05155

CFIR:

NAF01_12330

PDU:	PDUR_14345

PALB:

EJC50_00250

PBK:	Back11_46270 Back11_56650

PRZ:	GZH47_02235

PLYC:

GXP70_16895

PCEL:

HUB94_16800

PMAH:

PTQ21_19060

PAMY:

P9222_23805

PSPN:

L1F29_28875

PPAB:

KET34_15105

COHN:

KCTCHS21_28750

EUZ:	DVS28_a0141

MTU:

Rv0295c

MTV:	RVBD_0295c

MTC:

MT0308

MRA:

MRA_0304

MTF:	TBFG_10302

MTB:	TBMG_00300

MTK:	TBSG_00304

MTZ:	TBXG_000301

MTG:	MRGA327_01895

MTI:	MRGA423_01900

MTE:	CCDC5079_0274

MTUR:

CFBS_0313

MTL:	CCDC5180_0273

MTO:	MTCTRI2_0302

MTD:

UDA_0295c

MTN:	ERDMAN_0329

MTJ:	J112_01610

MTUB:

MT7199_0302

MTUC:

J113_02165

MTUE:

J114_01615

MTX:	M943_01550

MTUH:

I917_02110

MTUL:

TBHG_00294

MTUT:

HKBT1_0313

MTUU:

HKBT2_0313

MTQ:	HKBS1_0313

MBO:	BQ2027_MB0303C

MBB:

BCG_0335c

MBT:

JTY_0305

MBM:	BCGMEX_0305c

MBK:	K60_003170

MBX:

BCGT_0065

MAF:

MAF_02970

MMIC:

RN08_0337

MCE:	MCAN_03041

MCQ:	BN44_10339

MCV:	BN43_10334

MCX:	BN42_20021

MCZ:	BN45_10328

MORY:

MO_000313

MPA:

MAP_2118

MAO:

MAP4_1705

MAVI:

RC58_08520

MAVU:

RE97_08520

MAV:

MAV_2058

MIT:

OCO_20370

MIA:

OCU_20470

MID:

MIP_02867

MYO:

OEM_18200

MCHI:

AN480_10395

MIR:

OCQ_19040

MMAL:

CKJ54_08850

MMAN:

MMAN_20190 MMAN_35870(stf0)

MSA:	Mycsm_00285

MMI:

MMAR_4255

MMAE:

MMARE11_40680

MLI:	MULP_04434

MPSE:

MPSD_43910

MMC:

Mmcs_0389

MKM:

Mkms_0398

MJL:

Mjls_0377

MMM:

W7S_09550

MKN:	MKAN_07210

MYV:	G155_03115

MYE:	AB431_02465

MHAD:

B586_00830

MDX:	BTO20_32985

MSHG:

MSG_03818

MFJ:	MFLOJ_48450

MSTO:

MSTO_52360

MSIM:

MSIM_38380

MSAK:

MSAS_21000

MKU:	I2456_20070

MLW:	MJO58_20960

MXE:	MYXE_45730(stf0)

MNV:	MNVI_20490

MPAG:

C0J29_23360

MGOR:

H0P51_21545

MCOO:

MCOO_19370 MCOO_36480(stf0)

MBAI:

MB901379_03720

MSEO:

MSEO_21420

MHEK:

JMUB5695_04415(stf0)

MGAU:

MGALJ_48150

MLJ:	MLAC_08090

MBRD:

MBRA_11800(stf0)

MSHJ:

MSHI_03930

MMAM:

K3U93_18295

MSPG:

F6B93_02165

MOT:	LTS72_04005

MPAA:

MKK62_06175 MKK62_22750

MKY:	IWGMT90018_48810

MWU:	PT015_11180 PT015_19815

MSM:	MSMEG_0630

MSG:	MSMEI_0614

MSB:	LJ00_03130

MSN:	LI99_03130

MSH:	LI98_03130

MNE:	D174_03860

MYN:	MyAD_03775

MFT:	XA26_05680

MPHL:

MPHLCCUG_04751

MVQ:

MYVA_0396

MLL:	B1R94_02520

MRH:	MycrhN_1406

MHAS:

MHAS_04639(stf0)

MCHT:

MCHIJ_31410(stf0)

MAUU:

NCTC10437_00387

MMAG:

MMAD_06530

MMOR:

MMOR_00150 MMOR_00160 MMOR_61250

MAIC:

MAIC_52030(stf0)

MTY:	MTOK_09500(stf0)

MPSC:

MPSYJ_05460

MARZ:

MARA_34140

MGAD:

MGAD_46920

MHEV:

MHEL_17650(stf0)

MSAR:

MSAR_19950(stf0)

MANY:

MANY_44550

MAUB:

MAUB_37740(stf0)

MPHU:

MPHO_32720(stf0)

MMUC:

C1S78_001710

MMAT:

MMAGJ_14750

MBOK:

MBOE_17610

MFG:	K6L26_28680

MSEI:

MSEDJ_17360

MFLV:

NCTC10271_04720

MMON:

EWR22_02035

MGO:	AFA91_02415

MSEN:

K3U95_03100

MPAE:

K0O64_02080

MRF:	MJO55_01725

MDF:	K0O62_02935

MCRO:

MI149_02660

MGRO:

FZ046_08530

MAB:

MAB_1546c

MMV:	MYCMA_10710

MABB:

MASS_1642

MABL:

MMASJCM_1566

MCHE:

BB28_08395

MIZ:	BAB75_08380

MSTE:

MSTE_01538

MSAO:

MYCSP_06935

MSAL:

DSM43276_01403

RHA:	RHA1_ro01265

RER:

RER_01280

REY:

O5Y_00645

REB:	XU06_00660

RQI:	C1M55_00670

ROP:

ROP_09850

ROA:	Pd630_LPD05366

RHOD:

AOT96_11230

RTM:	G4H71_08705

RKO:	JWS14_06545

RPSK:

JWS13_39905

WHR:	OG579_18370

GBR:

Gbro_1563

GPO:	GPOL_c14170

GOR:

KTR9_1484

GTA:	BCM27_08230

GRU:	GCWB2_07780

GOM:	D7316_03681(stf0)

GAM:	GII34_06840

GPD:	GII33_06300

GJI:	H1R19_07610

GOI:	LK459_03005

GHN:	MVF96_07630

SPIN:

KV203_06105

TPR:

Tpau_3332

TSM:	ASU32_04780

SDX:	C4B68_38970

SRK:	FGW37_03665

CFL:

Cfla_3588

MIK:	FOE78_06760 FOE78_18310

MICG:

GJV80_11070

AFS:

AFR_20265

PLK:	CIK06_25695

PSUU:

Psuf_048710

NHY:	JQS43_16225

RXY:

Rxyl_2350

BALA:

DSM104299_03967(stf0)

AYM:	YM304_42100

DHI:	LH044_17705

CHON:

NIES4102_26330

CYL:	AA637_08080

HAO:	PCC7418_2773

PLP:	Ple7327_1126

SCS:	Sta7437_2176

STAN:

STA3757_24270

KBS:	EPA93_34475

DPD:	Deipe_2186

TRA:

Trad_0294

SOA:	G3M56_000720 G3M56_002420

GAU:

GAU_2069

RHOZ:

GXP67_29085

» show all

Reference

1 [PMID:15258569]

Authors

Mougous JD, Petzold CJ, Senaratne RH, Lee DH, Akey DL, Lin FL, Munchel SE, Pratt MR, Riley LW, Leary JA, Berger JM, Bertozzi CR

Title

Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis.

Journal

Nat Struct Mol Biol 11:721-9 (2004)
DOI:10.1038/nsmb802

Sequence

[msm:MSMEG_0630]

Reference

2 [PMID:15866533]

Authors

Pi N, Hoang MB, Gao H, Mougous JD, Bertozzi CR, Leary JA

Title

Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry.

Journal

Anal Biochem 341:94-104 (2005)
DOI:10.1016/j.ab.2005.02.004

Sequence

[msm:MSMEG_0630]

Other DBs

ExplorEnz - The Enzyme Database:

2.8.2.37

IUBMB Enzyme Nomenclature:

2.8.2.37

ExPASy - ENZYME nomenclature database:

2.8.2.37

BRENDA, the Enzyme Database:

2.8.2.37

DBGET integrated database retrieval system