| Entry |
|
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| Name |
tropinesterase;
tropine esterase;
atropinase;
atropine esterase
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| Class |
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
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| Sysname |
atropine acylhydrolase
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| Reaction(IUBMB) |
atropine + H2O = tropine + tropate [RN: R03563]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Also acts on cocaine and other tropine esters.
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| History |
EC 3.1.1.10 created 1961, deleted 1972, reinstated 1976
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| Pathway |
| ec00960 | Tropane, piperidine and pyridine alkaloid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Reference |
1 |
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| Authors |
Glick, D., Glaubach, S. and Moore, D.H. |
|---|
| Title |
Azolesterase activities of electrophoretically separated proteins of serum. |
|---|
| Journal |
J Biol Chem 144:525-528 (1942) |
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| Reference |
|
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| Authors |
Moog P, Krisch K. |
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| Title |
[The purification and characterization of atropine esterase from rabbit liver microsomes (author's transl)] |
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| Journal |
Hoppe Seylers Z Physiol Chem 355:529-42 (1974) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.1.10 |
| ExPASy - ENZYME nomenclature database: | 3.1.1.10 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 3.1.1.10 |
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