KEGG ENZYME: 3.1.1.110

ENZYME: 3.1.1.110

Entry

EC 3.1.1.110                Enzyme

Name

xylono-1,5-lactonase;
xylC (gene name);
D-xylono-1,5-lactone lactonase

Class

Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases

Sysname

D-xylono-1,5-lactone lactonohydrolase

Reaction(IUBMB)

D-xylono-1,5-lactone + H2O = D-xylonate [RN:R02427]

Reaction(KEGG)

R02427

Substrate

D-xylono-1,5-lactone [CPD:C02266];
H2O [CPD:C00001]

Product

D-xylonate [CPD:C00502]

Comment

The enzyme, found in bacteria, participates in the degradation of D-xylose. cf. EC 3.1.1.68, xylono-1,4-lactonase.

History

EC 3.1.1.110 created 2019

Pathway

ec00040

Pentose and glucuronate interconversions

ec01100

Metabolic pathways

Orthology

K14274

xylono-1,5-lactonase

Genes

SAVI:

JYB87_15485

PDJ:	D0907_16170

ALR:	DS731_20350

APEL:

CA267_011000

SALK:

FBQ74_03155

LAL:	AT746_16735

SAGA:

M5M_11590

MTHD:

A3224_13600

MAGA:

Mag101_00660

CSA:	Csal_0453 Csal_1727

CCAG:

SR908_16180

HSV:	HNO53_06500

HHAO:

QWG60_05160

HCAM:

I4484_06145

HSX:	HNO51_05810

HTX:	EKK97_06850

SAJS:

QO259_00280

RPI:

Rpic_4078

RPF:	Rpic12D_4190

RMN:	TK49_20875

RWE:	KOL96_02625

CBW:	RR42_s1947

CCUP:

BKK81_23070

CUP:	BKK80_33215

CUU:	BKK79_24105

BSAV:

WS86_09455

BGL:	bglu_1g22110

BGU:

KS03_3045

BGP:	BGL_1c15160

BPLA:

bpln_1g14880

BXE:

Bxe_C1362

BXB:

DR64_8448

BGE:	BC1002_6311

PSPW:

BJG93_31540

PACP:

FAZ97_29030

TVL:	FAZ95_35575

TCAR:

U0034_02920

RSB:	RS694_18450

RHY:	RD110_12070

RHG:	EXZ61_19560

ACK:	C380_10510

ACIO:

EAG14_03845

AAV:

Aave_2259

AAA:

Acav_2881

VAP:	Vapar_1040

VPE:	Varpa_1109

VPD:	VAPA_1c10930

VBO:	CKY39_05160

VAM:	C4F17_13990

HPSE:

HPF_09080(araB2)

HGR:	DW355_17135

STHM:

IS481_17800

PBH:	AAW51_0546

PAQA:

K9V56_007080

RGU:	A4W93_11075

HHT:	F506_05380

HEE:	hmeg3_16530

MTIM:

DIR46_22465

MASY:

DPH57_11380 DPH57_12555

MANC:

IV454_19205

MFY:	HH212_20325

MVAR:

MasN3_29220(xylC_1) MasN3_29420(xylC_2)

MENY:

LSQ66_03625 LSQ66_12020

MASZ:

C9I28_09445 C9I28_10615

MALI:

EYF70_20030 EYF70_21150

MUM:	FCL38_27880 FCL38_29050

MFLA:

GO485_23500 GO485_24790

MPLI:

E1742_23110 E1742_24295

TCT:	PX653_12305 PX653_13570

DUG:	HH213_05140 HH213_29255

DZO:	SR858_04230

TMJ:	P0M04_24825

RUG:	QC826_04530

EHB:	E7V67_006555 E7V67_007735

UND:	UNDKW_4175(xylC)

MRD:	Mrad2831_1323

MOR:

MOC_1680

MPHY:

MCBMB27_00978

METX:

A3862_24210

MMES:

MMSR116_17520

BBAR:

RHAL1_00794

MCG:

GL4_0247

CCR:

CC_0820

CCS:	CCNA_00863(xylC)

CAK:

Caul_4002

CSE:

Cseg_3555

CHQ:	AQ619_03675

CFH:	C1707_01240

CAUF:

CSW63_19055

CAUL:

KCG34_25080

PZU:	PHZ_c2467(gnl)

BSB:	Bresu_2946

BRG:	A4249_02075

BRL:	BZG35_07250

BVC:	CEP68_01690

BMED:

GYM46_01945

BPON:

IFE19_15295

BGOE:

IFJ75_11095

BVIT:

JIP62_01270

BALB:

M8231_01130

BFQ:	JX001_08130

BREA:

HZ989_05165

AEX:	Astex_1077 Astex_1910

TSV:	DSM104635_01758(araB_1) DSM104635_03103(araB_2)

NPP:	PP1Y_Mpl1116

NRE:	BES08_06910 BES08_15260 BES08_20250

NOV:	TQ38_020680 TQ38_022630

NOT:	C7W88_19795

NOR:	FA702_20275

NDR:	HT578_14240 HT578_16920

NHUM:

PQ457_09885

SAL:

Sala_0747

SPHQ:

BWQ93_10700

SINA:

KNJ79_12255 KNJ79_17420

SPHM:

G432_06495 G432_09685 G432_12865

STAX:

MC45_10355

SPHI:

TS85_11215

SSAN:

NX02_17665

SNJ:	A7E77_09050

SMY:	BJP26_04940

SPAN:

AWL63_01160

SKR:	BRX40_02255

SPLM:

BXU08_08395

SPLK:

AV944_00250

SPHC:

CVN68_09050

SPHF:

DM480_08655

SPAU:

DRN02_015795

SDH:	H9L15_10750

SPAP:

H3Z74_12340

SPII:

G7077_03990

SSIN:

G7078_02950

SSAU:

H8M03_07325

SARI:

H5J25_14765

SSUA:

FPZ54_11745

SBIN:

SBA_ch1_01320 SBA_ch1_21010(xylC)

SAER:

NEF64_10885

SMOR:

LHA26_13735

SQO:	NMP03_08205

SCAB:

LZK98_03555 LZK98_15040

SHAN:

PPZ50_09785

SNAP:

PQ455_15925

SNOS:

K8P63_08620

SSAG:

KV697_15385

SABI:

PBT88_03985

SJP:	SJA_C1-12860

SINB:

SIDU_07860

SYB:	TZ53_20795 TZ53_22170

SPMI:

K663_01025

SPHB:

EP837_02111(araB)

SPHR:

BSY17_1048 BSY17_2829

SPHT:

K426_04615

SHYD:

CJD35_07435

SYA:	A6768_03420 A6768_17790

SPYG:

YGS_C1P2072 YGS_C2P1109

SUFL:

FIL70_09980 FIL70_11325

SBAR:

H5V43_07695 H5V43_09805

SAMI:

SAMIE_1004010

BLAS:

BSY18_1344

BFW:	B5J99_16095

SPZR:

G5C33_10770

SPHS:

ETR14_15940

SFLV:

IC614_08285

SAND:

H3309_08365

POQ:	KZX46_04590 KZX46_07845

PMEA:

KTC28_03315 KTC28_06930

AAY:	WYH_02214(araB)

ADO:	A6F68_00103(araB_1)

CMAN:

A9D14_07170

QCI:	NCF85_07990

ERF:	FIU90_14250(araB)

POT:	E2E27_07760

GOX:

GOX1793

GOH:

B932_0278

GOY:	GLS_c19130

GAL:	A0U94_03065

GTI:	FXF46_09130

GSP:	IGS75_10355

GFA:	MKW11_08995

GDI:

GDI2179

GDJ:

Gdia_0398

GXY:

GLX_25580

GXL:

H845_501

KNA:	B0W47_12885

KEU:	S101446_02891

KSC:	CD178_00518(araB)

KRE:	GWK63_03420

KOI:	LV478_08435

AACE:

A0U92_01990

ABG:	Asbog_01907

KBA:	A0U89_03250

NCH:	A0U93_10730

NTN:	D5366_05805

NEH:	E3E11_07060

SSAM:

E3D00_07980

SWF:	E3E12_06380

BOB:	GN304_03130

BOMB:

GT348_02685

LCK:	HN018_08005

KHA:	IFJ82_12705

PARZ:

DTQ13_07390

ACIM:

GT370_05235

KDP:	N5W20_05020

NGU:	QN315_01970

AZL:	AZL_e03640

ALI:	AZOLI_p50378

ABS:	AZOBR_p440161

ABQ:	ABAZ39_31210 ABAZ39_31600

ABF:	AMK58_27055 AMK58_27390

ATI:	AL072_30995

AHU:	A6A40_14235

AZT:	TSH58p_18660 TSH58p_21365

AZM:	DM194_26430

AZZ:	DEW08_21995

AOZ:	HUE56_23210

AARE:

D3093_27375 D3093_27770

AZS:	E6C72_28395

NAO:	Y958_17430

NCB:	C0V82_25355

GSO:	PH603_05940

ACU:

Atc_2721

ACZ:	Acaty_c2569

MXA:

MXAN_3250

MYM:	A176_003701

MYX:	QEG98_17445

MFU:	LILAB_24030

MMAS:

MYMAC_003208

NANO:

G5V58_18995

» show all

Reference

1 [PMID:22709678]

Authors

Toivari M, Nygard Y, Kumpula EP, Vehkomaki ML, Bencina M, Valkonen M, Maaheimo H, Andberg M, Koivula A, Ruohonen L, Penttila M, Wiebe MG

Title

Metabolic engineering of Saccharomyces cerevisiae for bioconversion of D-xylose to D-xylonate.

Journal

Metab Eng 14:427-36 (2012)
DOI:10.1016/j.ymben.2012.03.002

Sequence

[ccr:CC_0820]

Reference

2 [PMID:25073011]

Authors

Nygard Y, Maaheimo H, Mojzita D, Toivari M, Wiebe M, Resnekov O, Gustavo Pesce C, Ruohonen L, Penttila M

Title

Single cell and in vivo analyses elucidate the effect of xylC lactonase during production of D-xylonate in Saccharomyces cerevisiae.

Journal

Metab Eng 25:238-47 (2014)
DOI:10.1016/j.ymben.2014.07.005

Other DBs

ExplorEnz - The Enzyme Database:

3.1.1.110

IUBMB Enzyme Nomenclature:

3.1.1.110

ExPASy - ENZYME nomenclature database:

3.1.1.110

BRENDA, the Enzyme Database:

3.1.1.110

DBGET integrated database retrieval system