KEGG   ENZYME: 3.1.1.71
Entry
EC 3.1.1.71                 Enzyme                                 
Name
acetylalkylglycerol acetylhydrolase;
alkylacetylglycerol acetylhydrolase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
Sysname
2-acetyl-1-alkyl-sn-glycerol acetylhydrolase
Reaction(IUBMB)
2-acetyl-1-alkyl-sn-glycerol + H2O = 1-alkyl-sn-glycerol + acetate [RN:R04043]
Reaction(KEGG)
R04043
Substrate
2-acetyl-1-alkyl-sn-glycerol [CPD:C03820];
H2O [CPD:C00001]
Product
1-alkyl-sn-glycerol [CPD:C02773];
acetate [CPD:C00033]
Comment
Hydrolysis of the acetyl group from the 1-alkyl-2-acetyl and 1-alkyl-3-acetyl substrates occurs at apparently identical rates. The enzyme from Erlich ascites cells is membrane-bound. It differs from lipoprotein lipase (EC 3.1.1.34) since 1,2-diacetyl-sn-glycerols are not substrates. It also differs from EC 3.1.1.47, 1-acetyl-2-alkyl-glycerophosphocholine esterase.
History
EC 3.1.1.71 created 1999
Reference
1  [PMID:2302414]
  Authors
Blank ML, Smith ZL, Cress EA, Snyder F.
  Title
Characterization of the enzymatic hydrolysis of acetate from alkylacetylglycerols in the de novo pathway of PAF biosynthesis.
  Journal
Biochim Biophys Acta 1042:153-8 (1990)
DOI:10.1016/0005-2760(90)90001-E
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.71
IUBMB Enzyme Nomenclature: 3.1.1.71
ExPASy - ENZYME nomenclature database: 3.1.1.71
BRENDA, the Enzyme Database: 3.1.1.71

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Protein sequence (960)   
   UniProt (945)   
   SWISS-PROT (5)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (5)   
   InterPro (5)   
All databases (982)   

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