KEGG   ENZYME: 3.1.2.25
Entry
EC 3.1.2.25                 Enzyme                                 
Name
phenylacetyl-CoA hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
Sysname
phenylglyoxylyl-CoA hydrolase
Reaction(IUBMB)
phenylglyoxylyl-CoA + H2O = phenylglyoxylate + CoA [RN:R07294]
Reaction(KEGG)
R07294
Substrate
phenylglyoxylyl-CoA [CPD:C15524];
H2O [CPD:C00001]
Product
phenylglyoxylate [CPD:C02137];
CoA [CPD:C00010]
Comment
This is the second step in the conversion of phenylacetyl-CoA to phenylglyoxylate, the first step being carried out by EC 1.17.5.1, phenylacetyl-CoA dehydrogenase.
History
EC 3.1.2.25 created 2004
Pathway
ec00360  Phenylalanine metabolism
ec01100  Metabolic pathways
Orthology
K18361  phenylacetyl-CoA:acceptor oxidoreductase
Genes
SHDSUTH_01622
EBAebA5393(padB)
ABREpbN1_03670(padB1) pbN1_05780(padB2)
APETToN1_39530(padB)
AZOazo1946(padB)
AOAdqs_2101
AZAAZKH_2904(padB)
AZIAzCIB_2845
AZDCDA09_15510
AZRCJ010_12705
TMZTmz1t_0199 Tmz1t_2959
TCLTchl_0104 Tchl_0789 Tchl_2139
TAKTharo_0098 Tharo_0858 Tharo_1297
ACOMCEW83_03765
DDZDSYM_17570
RPDRPD_1507
MAGXXM1_1873 XM1_2734
MAGNWV31_17125
MAGamb1241 amb2015
 » show all
Reference
1  [PMID:10336636]
  Authors
Rhee SK, Fuchs G
  Title
Phenylacetyl-CoA:acceptor oxidoreductase, a membrane-bound molybdenum-iron-sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica.
  Journal
Eur J Biochem 262:507-15 (1999)
DOI:10.1046/j.1432-1327.1999.00399.x
Reference
2  [PMID:9575237]
  Authors
Schneider S, Fuchs G.
  Title
Phenylacetyl-CoA:acceptor oxidoreductase, a new alpha-oxidizing enzyme that produces phenylglyoxylate. Assay, membrane localization, and differential production in Thauera aromatica.
  Journal
Arch Microbiol 169:509-16 (1998)
DOI:10.1007/s002030050604
Other DBs
ExplorEnz - The Enzyme Database: 3.1.2.25
IUBMB Enzyme Nomenclature: 3.1.2.25
ExPASy - ENZYME nomenclature database: 3.1.2.25
BRENDA, the Enzyme Database: 3.1.2.25
CAS: 57219-72-4

DBGET integrated database retrieval system