| Entry |
|
|---|
| Name |
deoxyribonuclease X;
Escherichia coli endodeoxyribonuclease;
Escherichia coli endodeoxyribonuclease X
|
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 3'-phosphomonoesters
|
|---|
| Reaction(IUBMB) |
Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes
|
|---|
| Comment |
Preference for supercoiled DNA; little activity on linear double-stranded DNA. Inhibited by single-stranded DNA, ATP and AMP.
|
|---|
| History |
EC 3.1.22.5 created 1992
|
|---|
| Reference |
1 |
|---|
| Authors |
Ghosh, S. and DasGupta, U. |
|---|
| Title |
Studies with endonuclease X: a new deoxyendonuclease of E. coli that preferentially cleaves supercoiled plasmid DNA. |
|---|
| Journal |
Curr Trends Life Sci 12:79-88 (1984) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.22.5 |
| ExPASy - ENZYME nomenclature database: | 3.1.22.5 |
|
|---|
