KEGG ENZYME: 3.1.3.34

ENZYME: 3.1.3.34

Entry

EC 3.1.3.34                 Enzyme

Name

deoxynucleotide 3'-phosphatase;
3'-deoxynucleotidase;
3'-deoxyribonucleotidase

Class

Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases

Sysname

2'-deoxyribonucleotide 3'-phosphohydrolase

Reaction(IUBMB)

a 2'-deoxyribonucleoside 3'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate [RN:R02751]

Reaction(KEGG)

Substrate

2'-deoxyribonucleoside 3'-phosphate [CPD:C00675];
H2O [CPD:C00001]

Product

2'-deoxyribonucleoside [CPD:C02269];
phosphate [CPD:C00009]

Comment

Also catalyses the selective removal of 3'-phosphate groups from DNA and oligodeoxyribonucleotides. Induced in Escherichia coli by T-even phages.

History

EC 3.1.3.34 created 1972

Orthology

Straboviridae polynucleotide kinase

Reference

1 [PMID:4289819]

Authors

Becker A, Hurwitz J.

Title

The enzymatic cleavage of phosphate termini from polynucleotides.

Journal

J Biol Chem 242:936-50 (1967)

Sequence

Other DBs

ExplorEnz - The Enzyme Database:

IUBMB Enzyme Nomenclature:

ExPASy - ENZYME nomenclature database:

BRENDA, the Enzyme Database:

CAS:	37288-18-9

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