| Entry |
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| Name |
thymidylate 5'-phosphatase;
thymidylate 5'-nucleotidase;
deoxythymidylate 5'-nucleotidase;
thymidylate nucleotidase;
deoxythymidylic 5'-nucleotidase;
deoxythymidylate phosphohydrolase;
dTMPase
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| Class |
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
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| Sysname |
thymidylate 5'-phosphohydrolase
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| Reaction(IUBMB) |
thymidylate + H2O = thymidine + phosphate [RN: R01569]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Acts on 5-methyl-dCMP and on TMP, but more slowly than on dTMP.
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| History |
EC 3.1.3.35 created 1972
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| Reference |
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| Authors |
Aposhian HV, Tremblay GY. |
|---|
| Title |
Deoxythymidylate 5'-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C. |
|---|
| Journal |
J Biol Chem 241:5095-101 (1966) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.3.35 |
| ExPASy - ENZYME nomenclature database: | 3.1.3.35 |
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